Clinical trials: Postoperative Analgesia After Cesarean Delivery
Transversus Abdominis Plane (TAP) Block, Wound Infiltration
Ultrasound-guided Transversus Abdominis Plane Block Versus Local Wound Infiltration (TAP_WI)
The goal of this clinical trial is to learn if transversus abdominis plane (TAP) block will reduce the cumulative opioid consumption compared to local wound infiltration (WI).
- Conditions
- Transversus Abdominis Plane (TAP) Block, Wound Infiltration, Pain Score (VAS), Opioid Analgesia
- Trial name
- TAP (NCT06627946)
- Testing
- TAP group
- Where
- Bhutan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Postoperative Pain, Caesarean Section
Intraperitoneal Hydrocortisone for Postoperative Pain and CRP Following Caesarean Section
The purpose of this study is to evaluate the clinical efficacy of intraperitoneal hydrocortisone 100 mg administration in reducing postoperative pain and inflammatory response in patients undergoing elective Caesarean section…
- Conditions
- Postoperative Pain, Caesarean Section, Peritoneal Inflammation
- Trial name
- NCT07892547
- Testing
- hydrocortisone, Nornal Saline
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Raditsya Mada Gautama, MD
Post-cesarean Pain Control Quality
Comparisons Between Low Thoracic and Lumbar Epidural Analgesia on Postoperative Pain Low Thoracic v.s. Lumbar Epidural for Post-cesarean Pain
Whether low thoracic epidural analgesia improves postoperative cesarean pain qualities than conventional lumbar epidural analgesia?
- Trial name
- NCT03946982
- Testing
- low thoracic epidural, lumbar epidural
- Where
- Taiwan
- Volunteers
- 189 people
- Sponsor
- National Taiwan University Hospital
Post Cesarean Section Pain
Optimal Intrathecal Morphine Dose for Better Post Cesarean Section Analgesia
Central neuraxial blocks (CNBs) remain the preferred anesthetic technique for cesarean section, with single shot spinal anesthesia (SSSA) being the standard practice at investigator's institute unless contraindicated.
- Trial name
- Analgesia (NCT07560501)
- Testing
- 0.5% bupivacaine heavy with fentanyl, 0.5% bupivacaine heavy with fentanyl plus morphine 50 mcg, 0.5% bupivacaine heavy with fentanyl plus morphine100 mcg
- Volunteers
- 180 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Pain, Postoperative, Caesarean Section
Infiltration Analgesia After Caesarean Section
Infiltration of a local anesthetic into the surgical wound is a simple method to strive to control postoperative pain after surgery. In the investigators institution, this method is used quite often.
- Trial name
- NCT01094106
- Testing
- Ropivacaine 0,75%, NaCl 0,9%
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- North Karelia Central Hospital
Postoperative Pain
Ultrasound-guided Quadratus Lumborum Block for Postoperative Pain Relief After Cesarean Delivery
The Quadratus Lumborum (QL) Block is an ultrasound-guided technique described by Rafael Blanco in 2007. The nerves to the lower abdominal wall can be anesthetized by injecting local anesthetics close to the anterior border of the…
- Trial name
- NCT02036749
- Testing
- nerve block
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Pain Management, Anxiety
Effects of EFT on Postpartum Safety Perception, Anxiety, and Postoperative Pain After Cesarean Section
This study is a parallel randomized controlled trial on 60 primiparous women with cesarean section pain, randomly divided into EFT and control groups.
- Trial name
- NCT06999564
- Testing
- EFT
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Pain, Postoperative
Ibuprofen Versus Ketorolac For Postoperative Pain Relief After Cesarean Section
The aim of this study will be to evaluate the effectiveness of intravenous ibuprofen versus intravenous ketorolac for postoperative pain relief after caesarian section 1.
- Trial name
- NCT05907993
- Testing
- Ibuprofen 800 mg
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Physiological Effect of Drugs, Morphine
Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine
The purpose of this study is to show that the effect of 3% 2-chloroprocaine prior to epidural morphine administration will be not inferior to the effect of epidural 2% lidocaine with 1:200,000 epinephrine on total opioid use for…
- Conditions
- Physiological Effect of Drugs, Morphine, Analgesics, Analgesics, Opioid
- Trial name
- NCT04369950
- Testing
- 2% lidocaine with 1:200,000 epinephrine and epidural morphine, 3% 2-chloroprocaine and epidural morphine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain After Cesarean Section, Postoperative Pain
Abdominal Ice Application After Cesarean Section
Cesarean section is one of the most commonly performed surgical procedures worldwide, and effective postoperative pain control is important for maternal recovery and patient comfort.
- Conditions
- Postoperative Pain After Cesarean Section, Postoperative Pain, Cesarean Section
- Trial name
- ICE-CS (NCT07626138)
- Testing
- Abdominal Ice Application, Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Nigde Omer Halisdemir University
Acute Post-operative Pain Following Caesarean Section
Opioid-free Analgesia for the Management of Acute Post-operative Pain Following Caesarean Section
Background: Multimodal analgesia; a combination of opioid and non-opioid analgesics, for management of acute post-operative pain significantly reduces the incidence of adverse effects associated with liberal post-operative opioid…
- Trial name
- OFAAPPCS (NCT04539249)
- Testing
- Magnesium sulphate, Pentazocine
- Where
- Nigeria
- Volunteers
- 324 people
- Sponsor
- Olakunle Ifeoluwa Makinde
Postoperative Pain
Quadratus Lumborum Block vs Intrathecal Morphine for Post-Cesarean Analgesia
İn this study, planned to compare the post-operative analgesic efficacy of Intrathecal Morphine Administration and anterior Quadratus lumborum Block in elective cesarean section operations.
- Trial name
- NCT06612424
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, İNTRATECHAL MORPHİNE GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Pain
Regional Midazolam in Quadratus Lumborum Block
Midazolam has been used in regional anesthesia of brachial plexus block; it has offered accepted postoperative pain relief. This study will use it in as an adjuvant to bupivacaine 0.25% in quadratus lumborum block in caesarean…
- Trial name
- NCT05261672
- Testing
- Midazolam/ bupivaciane, Bupivacain
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post-surgical Pain
Hydromorphone Hydrochloride Epidural Preemptive Analgesia for Postoperative Pain After Cesarean Section
Acute pain often occurs after cesarean section, which can lead to stress and inflammatory response in the body, which will not only affect the postpartum recovery speed of the puerpera, but also inhibit the secretion of prolactin…
- Trial name
- HHEPA (NCT06823180)
- Testing
- Hydromorphone hydrochloride low dose, Hydromorphone hydrochloride high dose, 0.9% sodium chloride
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Liquan Liang
Pain, Analgesia
Impact of the NeuroCuple Device on Pain Management After Cesarean Delivery
This will be a single-center, sham-controlled, 3 arms, randomized (1:1:1) prospective study in females undergoing cesarean delivery to investigate the impact of NeuroCuple™ non-pharmacological analgesic device for management of…
- Conditions
- Pain, Analgesia, Pregnancy
- Trial name
- NCT07185425
- Testing
- NeuroCuple
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Inova Health Care Services
Acute Postoperative Pain After Cesarean Delivery
LI4 and SP6 Acupuncture for Pain After Cesarean Delivery
This randomized, sham-controlled clinical trial will evaluate the effectiveness of acupuncture at bilateral LI4 and SP6 as an adjunct to standard postoperative analgesia for acute pain after cesarean delivery.
- Trial name
- NCT07869589
- Testing
- Bilateral Acupuncture Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Nigde Omer Halisdemir University
S-ketamine, Analgesia, Patient-Controlled
The Effect of S-ketamine Combined With Sufentanil for Postoperative Analgesia in Patients Following Cesarean Section
This randomized controlled trial is designed to investigate the effect of low-dose of S-ketamine combined with sufentanil for postoperative patient-controlled intravenous analgesia in patients following cesarean section.
- Conditions
- S-ketamine, Analgesia, Patient-Controlled, Cesarean Section
- Trial name
- NCT05299866
- Testing
- S-ketamine
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Ling Dong
Spinal Anesthesia, Cesarean Section Pain
Effect of Single-Dose Dexamethasone on Postoperative Pain After Cesarean Section Under Spinal Anesthesia
This study looked at whether giving a single dose of dexamethasone (a steroid medicine, 8 mg given into the vein) before a cesarean section could reduce pain after the operation.
- Conditions
- Spinal Anesthesia, Cesarean Section Pain, Postoperative Pain
- Trial name
- NCT07718360
- Testing
- Dexamethasone (IV), Normal Saline 0.9% Infusion Solution
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- KRL Hospital, Islamabad
Cesarean Section, Pain, Acute
Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)
The investigators are comparing post operative analgesia provided for caesarean section patients, with the quadratus lumborum type 2 block and intrathecal morphine.
- Trial name
- NCT03267628
- Testing
- Intrathecal morphine as well as local anaesthetic in Blocks, Intrathecal morphine as well as saline in Block, Saline intrathecal as well as saline in Blocks
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr Willem Basson
Cesarean Section, Dexamethasone
Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia
The management of postpartum pain is essential to ensure early rehabilitation for parturients. Intravenous dexamethasone has a potent analgesic action when used in the context of general anesthesia.
- Conditions
- Cesarean Section, Dexamethasone, Postoperative Pain, Spinal Anesthesia
- Trial name
- NCT05535036
- Testing
- Dexamethasone 4mg
- Where
- Tunisia
- Volunteers
- 84 people
- Sponsor
- Mongi Slim Hospital