Clinical trials: Postoperative Atrial Fibrillation
Postoperative Atrial Fibrillation
Prevention of Postoperative Atrial Fibrillation
The primary aim of this study is to determine the safest and most effective therapeutic strategy to decrease the incidence of postoperative atrial fibrillation following cardiac surgery in an era with shorter ICU and hospital…
- Trial name
- NCT01742039
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- George Washington University
Persistent Atrial Fibrillation
Pulsed Field Ablation Versus Radiofrequency Ablation: Effects of Pulmonary Vein Isolation Combined With Left Atrial Posterior Wall Isolation on Postoperative Gastric Motility in Patients With Persistent Atrial Fibrillation
This is a single-center, prospective, matched cohort study comparing the effect of Pulsed Field Ablation (PFA) versus Radiofrequency Ablation (RF) on postoperative gastric motility in patients with persistent atrial fibrillation…
- Trial name
- PFA-GM (NCT07612241)
- Testing
- Pulsed Field Ablation, Radiofrequency Ablation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Atrial Fibrillation, Arrhythmias, Cardiac
Low Workload Concept for the Detection of Silent Atrial Fibrillation (AF) and Atrial Fibrillation Burden in Patients At High Risk of AF and Stroke
Patient-centered novel e-health technology and services will lay the foundation for future healthcare systems and services to support health and welfare promotion.
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- CARE-DETECT (NCT05351775)
- Testing
- Smartphone application, Bed sensor, Wrist-worn photoplethysmography (PPG) and accelerometer data logger.
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- University of Turku
Cardiac Surgery, Post-pericardiotomy Syndrome
COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial)
This is a multicenter, double-blind, randomized trial to assess the efficacy and safety of colchicine for post-pericardiotomy syndrome prevention, post-operative effusions prevention, and post-operative atrial fibrillation…
- Conditions
- Cardiac Surgery, Post-pericardiotomy Syndrome, Atrial Fibrillation, Pericardial Effusion
- Trial name
- COPPS-2 (NCT01552187)
- Testing
- Colchicine
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- Maria Vittoria Hospital
Atrial Fibrillation
"UNMASKING Study" For Atrial Fibrillation Recurrences Typing in Early Postoperative Period
The aim of this study is to identify the most appropriate method for managing patients with AF recurrences after the first ablation procedure, through the diagnostic data stored by a subcutaneous AF monitor.
- Trial name
- NCT01164319
- Testing
- Circumferential PVI and subcutaneous cardiac monitor implantation
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Atrial Fibrillation
The Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery-Extended Follow-Up
The purpose of the Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery (PALACS, NCT02875405) trial was to determine if performing posterior left pericardiotomy at the time of cardiac…
- Trial name
- PALACS-EF (NCT05903222)
- Testing
- Non-Interventional
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Weill Medical College of Cornell University
Atrial Fibrillation
Impact of Sodium-glucose Cotransporter 2 Inhibitors on Post-operative Atrial Fibrillation in Cardiothoracic Surgery
SGLT2 inhibitors are oral anti-diabetic medications that were found to improve cardiorenal outcomes in patients with type 2 diabetes mellitus (DM), chronic heart failure with reduced and preserved ejection fraction, and chronic…
- Trial name
- NCT06251453
- Testing
- SGLT2 inhibitor
- Where
- 2 sites in Qatar
- Volunteers
- 3,280 people
- Sponsor
- Hamad Medical Corporation
Atrial Fibrillation, Atrial Flutter
Detection of Atrial Fibrillation After Cardiac Surgery
The aim of the SEARCH-AF trial is to evaluate a novel diagnostic tool for detecting post-operative atrial fibrillation or flutter (POAF/AFL) in cardiac surgical subjects during the early, sub-acute post-operative period.
- Conditions
- Atrial Fibrillation, Atrial Flutter, C.Surgical Procedure; Cardiac, Arrhythmias, Cardiac
- Trial name
- SEARCH-AF (NCT02793895)
- Testing
- Medtronic SEEQ™ mobile cardiac telemetry system, Usual Care, CardioSTAT (Icentia Inc.) cardiac rhythm monitoring device
- Where
- 10 sites in Canada
- Volunteers
- 336 people
- Sponsor
- Unity Health Toronto
Coronary Artery Disease
Prophylactic Maze to Prevent Atrial Fibrillation in Adult Cardiac Surgery
This study will look at performing a prophylactic limited left sided maze procedure during concomitant adult cardiac surgery to prevent the common occurrence of postoperative atrial fibrillation.
- Trial name
- PREVENT-AF (NCT03604432)
- Testing
- propylactic maze
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Corewell Health West
Atrial Fibrillation
The Occurrence of Atrial Fibrillation After Totally Endoscopic Cardiac Surgery
The aim of this study is to investigate the occurrence of new-onset postoperative atrial fibrillation after totally endoscopic cardiac surgery.
- Trial name
- AFMICS-II (NCT05633797)
- Testing
- FibriCheck
- Where
- Belgium
- Volunteers
- 152 people
- Sponsor
- Jessa Hospital
Post-operative Atrial Fibrillation
Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery
Metoprolol is frequently administered to cardiac surgery patients to reduce the incidence of postoperative atrial fibrillation (PoAF).
- Trial name
- PREEMPTIVE (NCT03943927)
- Testing
- Guided Metoprolol Management
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Death, Stroke
Postoperative Atrial Fibrillation and Long-term Survival
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
- Conditions
- Death, Stroke, Myocardial Infarction
- Trial name
- POAF (NCT02349269)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Stroke
PERIOP 2 - A Safety and Effectiveness of LMWH vs Placebo Bridging Therapy for Patients on Long Term Warfarin Requiring Temporary Interruption of Warfarin.
The purpose of the study is to determine the effectiveness and safety of LMWH postoperative bridging therapy (standard of care) versus postoperative placebo bridging therapy (experimental arm)for patients with mechanical heart…
- Trial name
- NCT00432796
- Testing
- Dalteparin
- Where
- 8 sites in Canada, India
- Volunteers
- 1,473 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Atrial Fibrillation, Esophageal Carcinoma
Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer
This phase II trial studies how well amiodarone works in the prevention of atrial fibrillation (AF) after a minimally invasive esophagectomy (MIE) in patients with esophageal cancer.
- Trial name
- NCT06067438
- Testing
- Amiodarone Hydrochloride, Saline
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- OHSU Knight Cancer Institute
Atrial Fibrillation
Effects of Topical Local Anesthesia of Pulmonary Vein Combined With Vagus Nerve Block on the Incidence of Atrial Fibrillation After Thoracic Surgery
This study intends to explore a new therapy to reduce the incidence of atrial fibrillation in thoracic patient who receive video-assisted thoracoscopic lobectomy .The results of the study are to assess the effects of this new…
- Trial name
- NCT03919786
- Testing
- topical local anesthesia of pulmonary vein combined with vagus nerve block
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Han Yuan
Pain, Postoperative, Atrial Fibrillation
BRS and Outcomes in Cardiothoracic Surgery
The purpose of this study is to determine whether baroreceptor sensitivity (the ability of your body to change your heart rate and/or blood pressure in response to a situation) has any effect on how likely you are to suffer…
- Conditions
- Pain, Postoperative, Atrial Fibrillation, Cognitive Dysfunction
- Trial name
- NCT03243279
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
Atrial Fibrillation New Onset
Cost-effectiveness Analysis Between Two Anticoagulation Strategies for Atrial Fibrillation in the Postoperative Period of Coronary Artery Bypass Graft Surgery
Coronary artery bypass graft (CABG) surgery is a common intervention in patients with coronary artery disease (CAD). The presence of new postoperative atrial fibrillation / atrial flutter (POAF) occurs in 15-40% of patients…
- Trial name
- TASK-POAF (NCT05300555)
- Testing
- Rivaroxaban 20 MG Oral Tablet, Warfarin
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Arterial Disease (CAD), Valve Replacement
Prolonged Chest Tube Treatment to Reduce Rates of Atrial Fibrillation Following Cardiac Surgery
Evacuation of pericardial blood by posterior pericardiotomy or use of a posterior pericardial chest tube lowers postoperative atrial fibrillation (POAF) rates after cardiac surgery by 45-68%.
- Conditions
- Coronary Arterial Disease (CAD), Valve Replacement, Aortic Surgery
- Trial name
- PROPER (NCT06800781)
- Testing
- Prolonged treatment with posterior pericardial chest tube plus standard care
- Where
- Sweden
- Volunteers
- 624 people
- Sponsor
- Region Skane
Postoperative Atrial Fibrillation, Post PCI Atrial Fibrillation
Atrial Fibrillation After CABG and PCI
Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice and is associated with an increased risk of stroke, heart failure and death.
- Conditions
- Postoperative Atrial Fibrillation, Post PCI Atrial Fibrillation, Stroke, Oral Anticoagulation
- Trial name
- AFAF (NCT04307225)
- Testing
- Zenicor
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Coronary Artery Bypass Grafting, Remimazolam
Remimazolam for Postoperative Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac severe arrhythmia globally and is associated with an increased risk of mortality and morbidity, with a loss of 6.0 million disability-adjusted life-years worldwide in 2017…
- Trial name
- RePAF (NCT05891145)
- Testing
- Remimazolam, midazolam
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University