Clinical trials: Postoperative Atrial Fibrillation
Atrial Fibrillation, Coronary Artery Disease
Preoperative Oral Magnesium to Prevent Postoperative Atrial Fibrillation Following Coronary Surgery (POMAF-CS)
Post operative atrial fibrillation following coronary surgery (POAF) is a common complication that can affect 10-50% of patients. Intravenous magnesium, administered per-or post-operatively, reduces the incidence of POAF.
- Conditions
- Atrial Fibrillation, Coronary Artery Disease, Surgery--Complications
- Trial name
- POMAF-CS (NCT03703349)
- Testing
- Magnesium Sulfate
- Where
- Lebanon
- Volunteers
- 200 people
- Sponsor
- St Joseph University, Beirut, Lebanon
Coronary Artery Bypass
Atorvastatin for Prevention of Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting Surgery
The purpose of this study is to determine whether pretreatment with atorvastatin protects against atrial fibrillation following off-pump coronary artery bypass graft surgery.
- Trial name
- NCT00611143
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Samsung Medical Center
Coronary Heart Disease
Supplementation With Polyphenol-Rich Foods and Atrial Fibrillation After a Cardiac Surgery
Post-operative atrial fibrillation (POAF) is a major cause of morbidity and mortality after a cardiac surgery. Both systemic inflammation and oxidative stress play a role in the initiation of POAF after a cardiac surgery.
- Trial name
- Polyphemus (NCT02045134)
- Testing
- High-anthocyanin rich corn flour
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Neuromed IRCCS
Coronary Artery Bypass Graft Surgery
Vitamin C in Cardiac Surgery Patients
Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery that increases the incidence of stroke, kidney injury and death.
- Trial name
- NCT03123107
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Geisinger Clinic
Sleep, Atrial Fibrillation
Impact of Sleep Quality on Outcomes After Cardiac Surgery
Sleep is a basic human need and is essential for good quality of life, good health. In fact, humans spend one third of their life time in sleeping or attempting to do so.
- Conditions
- Sleep, Atrial Fibrillation, Delirium, Postoperative, Complications, Postoperative
- Trial name
- NCT06527105
- Testing
- Eye masks and ear plugs
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amrita Institute of Medical Sciences & Research Center
Atrial Fibrillation
Vitamin C and Atrial Fibrillation After Cardiac Surgery
The purpose of this study is to determine if vitamin C decreases the chance of developing atrial fibrillation, a type of arrhythmia or irregular heartbeat, following cardiac surgery.
- Trial name
- NCT01580683
- Testing
- Ascorbic Acid
- Where
- United States
- Sponsor
- Regional Hospital of Scranton
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Postoperative Atrial Fibrillation
Microvascular Effects of Intravenous Esmolol During Postoperative Atrial Fibrillation
Background: Postoperative atrial fibrillation (POAF) is commonplace after cardiothoracic surgery. A rate control strategy by using short-acting beta blockers is recommended as a first-line therapy in patients without hemodynamic…
- Trial name
- FANI (NCT03646773)
- Volunteers
- 25 people
- Sponsor
- Hospices Civils de Lyon
Atrial Fibrillation New Onset
PARADISE: Predicting AF After Cardiac Surgery
The PARADISE study aims to develop and validate prediction tools to identify patients at risk of Atrial Fibrillation (AF) after cardiac surgery.
- Trial name
- PARADISE (NCT05255224)
- Testing
- Not applicable as observational study
- Where
- United Kingdom
- Volunteers
- 13,684 people
- Sponsor
- University of Oxford
Postoperative Atrial Fibrillation
Multiparametric MRI Assessment of Atrial Heart Disease as a Predictor of Atrial Fibrillation After Myocardial Revascularization Surgery
Postoperative atrial fibrillation (POAF) occurs in 20-40% of patients undergoing coronary artery bypass grafting (CABG) and is a marker of atrial vulnerability.
- Trial name
- IRM-FAPO (NCT04657835)
- Testing
- 4D cardiac MRI with gadoteric acid, Blood sample, Implantable Loop Recorder (ILR)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cardiac Surgery
Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF)
Over the past few years, research has focused on the prevention of atrial fibrillation (AF) after cardiac surgery, but highly effective interventions are still missing.
- Trial name
- BOTAF (NCT04075981)
- Testing
- Botulinum Toxin Type A Injection [Xeomin]
- Where
- 7 sites in France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
POAF, Atrial Fibrillation (AF)
Association of Lipoprotein(a) With Postoperative Atrial Fibrillation
About one in three patients who undergo open-heart surgery develop an irregular heart rhythm called postoperative atrial fibrillation (POAF).
- Trial name
- LPa and POAF (NCT07737444)
- Volunteers
- 20 people
- Sponsor
- Anthony Tang
Atrial Fibrillation New Onset
Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients Pilot Trial
The START-POAF pilot study is a prospective, open-label two-arm, randomized controlled trial with blinded assessment of outcomes (PROBE).
- Trial name
- START-POAF (NCT05841056)
- Testing
- Amiodarone Hydrochloride 200 MG
- Where
- 2 sites in Canada
- Volunteers
- 400 people
- Sponsor
- Population Health Research Institute
Atrial Fibrillation
Gene Expression Profiling in Subjects With Postoperative Atrial Fibrillation After Cardiac Surgery (GENEXPRO Surg)
Atrial fibrillation is a type of irregular heartbeat that is common after having heart surgery. There may be many different reasons why some people get atrial fibrillation after their heart surgery.
- Trial name
- NCT00833313
- Testing
- Atrial biopsy
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Brigham and Women's Hospital
Postoperative Atrial Fibrillation
The Effect of Intra Operative Dexmedetomidine in Prevention of Early Postoperative Atrial Fibrillation
The incidence of atrial fibrillation (AF) after lung resection varies between 12% and 30% after lobectomy and 23%-67% after pneumonectomy. The average time of onset of AF after lung resection is 2-3 days.
- Trial name
- NCT05320705
- Testing
- Intra Operative Dexmedetomidine
- Where
- Egypt
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Atrial Fibrillation
The Effect of Preoperative SGB on POAF After VATS
The aim of this study is to test if stellate ganglion block can decrease the incidence of atrial fibrillation after video-assisted thoracoscopic surgery and the way it works.
- Trial name
- NCT05753644
- Testing
- stellate ganglion blocks, Ropivacaine
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Peking University People's Hospital
Atrial Fibrillation
Study to Evaluate the Effectiveness of SGB in Preventing Post-op Atrial Fibrillation
Atrial fibrillation requires both an initiation trigger and favorable environment for maintenance and the sympathetic and parasympathetic nervous systems play important roles in this regard.
- Trial name
- NCT03269383
- Testing
- Bupivacaine, Saline
- Where
- United States
- Sponsor
- Christopher Connors, MD
Postoperative Atrial Fibrillation, Thoracic Surgery
Diagnosis of Atrial Fibrillation in Postoperative Thoracic Surgery Using a Smartwatch
Postoperative atrial fibrillation (POAF) occurs in approximately 20% of patients following thoracic surgery. Early diagnosis is essential to prevent complications such as heart failure, stroke, myocardial infarction, and…
- Conditions
- Postoperative Atrial Fibrillation, Thoracic Surgery, Smartwatches, Rhythm Monitoring
- Trial name
- THO-FA-WATCH (NCT06724718)
- Testing
- smartwatch, ECG
- Where
- France
- Volunteers
- 302 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Atrial Fibrillation
ALDOsterone for Prediction of Post-Operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is a major and frequent complication occurring after cardiac surgery, contributing to prolonged intensive care and hospital stays and is associated with several cardiovascular…
- Trial name
- ALDO-POAF (NCT02814903)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
The Cardiac Function
Postoperative Arrhythmia and Preoperative Cardiac Function
This study aims to investigate the association between echocardiographic parameters-including preoperative cardiac echo, as well as postoperative follow-up echocardiography and other associated parameters-and the risk factors…
- Trial name
- NCT06999681
- Testing
- No Interventions
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital