Clinical trials: Postoperative Atrial Fibrillation
Cardiac Surgery, Peri Operative Medicine
Risk Factors of Atrial Fibrillation After Cardiac Surgery
Supraventricular arrhythmias complicate more than 40% of cardiac surgeries and are associated with an increased risk of bleeding, stroke, heart failure, and death.
- Conditions
- Cardiac Surgery, Peri Operative Medicine, Thoracic Surgery, Cardiopulmonary Bypass
- Trial name
- PFAS (NCT07625033)
- Where
- France
- Volunteers
- 918 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Atrial Fibrillation, Post-Op Complication
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG)…
- Trial name
- NCT06063538
- Testing
- CardiaMend in Combination with Amiodarone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Chicago
Postoperative Atrial Fibrillation, Cardiac Tamponade
Posterior Pericardiotomy for Prevention of POAF After Cardiac Surgery: RCT in Yemen
A single-center, randomized controlled trial in Yemen evaluating whether posterior pericardiotomy (PP) reduces postoperative atrial fibrillation (POAF) after open-heart surgery.
- Trial name
- PP-POAF (NCT07266935)
- Testing
- Posterior Pericardiotomy, Standard Care
- Where
- Yemen
- Volunteers
- 210 people
- Sponsor
- Taiz University - Faculty of Medicine
Coronary Artery Bypass Grafting, Postoperative Atrial Fibrillation
Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery
The goal of this interventional clinical trial is compare between two different dose regimens of bisoprolol (beta-blocker) in CABG patients in terms of efficacy and safety.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Atrial Fibrillation, Coronary Artery Disease
- Trial name
- NCT05730413
- Testing
- Bisoprolol
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Postoperative Atrial Fibrillation
Effect of Alpha-Lipoic Acid Supplementation on the Incidence of Postoperative Atrial Fibrillation in Cardiac Surgery Patients
ALA is administered orally since it is without difficulty absorbed in the stomach. ALA goes through the blood brain barrier and does not show toxic effects and actions at doses used for prophylactic and therapeutic purposes.
- Trial name
- NCT06151652
- Testing
- Alpha Lipoic Acid 600 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 350 people
- Sponsor
- Ain Shams University
Atrial Fibrillation
Amiodarone to Prevent Post-Operative Arrhythmias
Rapid heart rhythms originating from the upper heart chambers (atrial tachyarrhythmias) are very common after open-heart surgery.
- Trial name
- NCT00251706
- Testing
- amiodarone
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Calgary
Atrial Fibrillation, Atrial Flutter
A Retrospective Analysis of the Use of ACE-inhibitors and Angiotensin Receptor Blockers
It is well known that atrial fibrillation (AF) and atrial flutter occur frequently after most types of cardiac surgeries.(1-4) Postoperative AF is associated with significant morbidity, longer hospital stay, and higher related…
- Trial name
- NCT00321945
- Testing
- ACE-Inhibitors and Angiotensin Receptor Blockers
- Where
- 3 sites in United States
- Volunteers
- 546 people
- Sponsor
- Emory University
Postoperative Atrial Fibrillation
Post-Operative Atrial Fibrillation After Surgical Aortic Valve Replacement and the Influence of Statins
Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery.
- Trial name
- NCT05062239
- Testing
- Discontinuance of treatment with statins 7 to 14 days prior to surgery until 30 days postoperative, No-intervention.
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Lars Peter Riber
Atrial Fibrillation, Cardiac Surgery
Postoperative New-onset Atrial Fibrillation in Cardiac Surgery: DECS-PNAF Project
The DExamethasone for Cardiac Surgery - Postoperative New-onset Atrial Fibrillation (DECS-PNAF) project described in this protocol aims to elucidate how corticosteroids protect cardiac surgical patients from Postoperative…
- Trial name
- DECS-PNAF (NCT01143129)
- Testing
- Dexamethasone
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- UMC Utrecht
Atrial Fibrillation New Onset
Silymarin for the Prevention of Atrial Fibrillation After Cardiac Surgery
The study is a prospective, randomized, controlled trial to assess the effects of silymarin on the occurrence of postoperative atrial fibrillation after coronary artery bypass graft surgery.
- Trial name
- NCT06114719
- Testing
- Silymarin
- Where
- Serbia
- Volunteers
- 160 people
- Sponsor
- University of Novi Sad
Atrial Fibrillation, Surgery--Complications
Novel Methods for Characterizing Patients With Post-operative Atrial Fibrillation Secondary to Abdominal Surgery
Purpose The primary purpose of the current project is to characterize unselected patients undergoing surgery developing post-operative atrial fibrillation (POAF), ultimately leading to a new risk-stratification model.
- Trial name
- NCT04090918
- Testing
- Cardiac examination programme 3 months after abdominal surgery
- Where
- Denmark
- Sponsor
- Frederiksberg University Hospital
Postoperative Atrial Fibrillation
Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment
Patients undergoing first time cardiac surgery will undergo rapid atrial pacing prior to initiation of cardiopulmonary bypass to screen for AF inducibility.
- Trial name
- NCT03868150
- Testing
- Amiodarone Injection, Intraoperative Rapid Atrial Pacing
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Stanford University
Postoperative Atrial Fibrillation
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement
Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery.
- Trial name
- STARC (NCT05076019)
- Testing
- Atorvastatin 80mg
- Where
- Denmark
- Volunteers
- 266 people
- Sponsor
- Odense University Hospital
Post Operative Atrial Fibrillation
Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing isolated cardiac arterial bypass…
- Trial name
- CAMP POAF (NCT05681182)
- Testing
- CardiaMend with the Addition of Amiodarone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- WakeMed Health and Hospitals
Post-operative Atrial Fibrillation, Cardiovascular Diseases
Association Between GalectiN-3 and pOSt-operative atrIal Fibrillation After Coronary Artery bypaSs Graft
The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG).
- Conditions
- Post-operative Atrial Fibrillation, Cardiovascular Diseases, Post-pericardiotomy Syndrome
- Trial name
- GNOSIS (NCT06768528)
- Testing
- Galectin-3 dosage
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Atrial Fibrillation, Coronary Artery Bypass Grafting
Reduction of Atrial Fibrillation Study in Patients Undergoing Coronary Artery Bypass Grafting. (RASCABG 1 Study)
The purpose of this study is to determine whether postoperatively oral treatment with high dosis amiodarone for five days after intravenously admitted bolusinfusion will minimize the risk for development of atrial fibrillation…
- Trial name
- NCT00287209
- Testing
- Amiodarone
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- University of Aarhus
Atrial Fibrillation
The Effect of Magnesium Therapy to Prevent Post-operative Atrial Fibrillation After Cardiac Surgery in Adults
It is well known that magnesium sulfate has a membrane stabilizing effect , and broad spectrum anti arrhythmic properties. In this trial, the investigators study its prophylactic effect against atrial fibrillation in…
- Trial name
- NCT02928315
- Testing
- Magnesium Sulfate, control
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Cardiac Disease
Combined Amiodarone and Electrical Cardioversion for Postoperative Atrial Fibrillation After Cardiac Surgery
To determine the efficacy of cardioversion and amiodarone for cardiac patients who develop postoperative atrial fibrillation
- Trial name
- NCT01558128
- Testing
- Amiodarone, Cardioversion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Weill Medical College of Cornell University
Post-Operative Atrial Fibrillation
Botulinum Toxin Type A (AGN-151607) for the Prevention of Post-operative Atrial Fibrillation in Adult Participants Undergoing Open-chest Cardiac Surgery (NOVA)
This was a multi-center, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study to evaluate the efficacy and safety of botulinum toxin type A (AGN-151607) injections into the epicardial fat pads, foci of…
- Trial name
- NCT03779841
- Testing
- AGN-151607
- Where
- 32 sites in United States, Austria and 7 more
- Volunteers
- 323 people
- Sponsor
- AbbVie
Atrial Fibrillation
Influence of Vitamin C on Post-operative Atrial Fibrillation
Post-operative atrial fibrillation (POAF) is the most common arrhythmia which typically develops 2-3 days after cardiac surgery.
- Trial name
- NCT03592680
- Testing
- Vitamin C
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares