Clinical trials: Postoperative Bowel Function
HIPEC, Gastro Intestinal Cancer
Effects of HIPEC on Postoperative Bowel Motility and Complications
This retrospective cohort study was conducted at our institution, involving patients with gastric cancer, appendiceal mucinous neoplasm, or colon cancer who underwent CRS with or without HIPEC between January 2017 and December…
- Conditions
- HIPEC, Gastro Intestinal Cancer, Adhesion Prevention, Bowel Functions
- Trial name
- NCT07353177
- Testing
- Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
- Where
- China
- Volunteers
- 193 people
- Sponsor
- Peking University People's Hospital
Diverticulitis of Sigmoid
Bowel Function/QoL After Elective Sigmoidectomy vs. Conservative Management for Recurrent Uncomplicated Diverticulitis
The decision to perform a surgical intervention or not after recovery from repeated uncomplicated episodes of acute diverticulitis remains controversial and the literature shows different conflicting approaches based on…
- Trial name
- NCT03994978
- Testing
- elective sigmoidectomy
- Where
- Switzerland
- Volunteers
- 252 people
- Sponsor
- University Hospital, Basel, Switzerland
Surgery, Colorectal Cancer
Postoperative Electrical Muscle Stimulation Two
Undesirable loss of skeletal muscle mass (atrophy) is a common feature of many diseases as well as ageing, bed rest and physical inactivity.
- Conditions
- Surgery, Colorectal Cancer, Muscle Atrophy, Cancer Gi
- Trial name
- POEMS2 (NCT06964438)
- Testing
- Neuromuscular Electrical Stimulation, Protein supplement drink
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Nottingham
Colon Cancer
Effect of Omega-3 Fatty Acids on the Perioperative Immune Response and Erythrocyte Function
Ideally, the postoperative inflammatory response is part of a well-orchestrated mechanism that contributes to tissue healing and rapid recovery.
- Trial name
- EMPIRE (NCT02231203)
- Testing
- Omegaven
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Medical Center Alkmaar
Post-Op Complication
Impact of Varying Doses of Prucalopride on Improving Gut Function Recovery After Elective Colorectal Surgery
Postoperative ileus (POI) is a common complication after abdominal surgery, causing symptoms like nausea, vomiting, abdominal distension, and delayed passage of flatus and stool.
- Trial name
- NCT06816407
- Testing
- Prucalopride 2mg, Prucalopride 4mg, Standard Care
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Future University in Egypt
Pain, Postoperative
Multimodal Analgesic Using Morphine and COX-2 With or Without Dexmedetomidine for Colorectal Surgery
Recently, multimodal approach for postoperative pain control has been advocated.Combinations of traditional and novel pharmacological agents are administered, aiming to improve analgesia, spare opioid consumption, minimise…
- Trial name
- NCT01353456
- Testing
- Dexmedetomidine, Normal Saline
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Colorectal Cancer, Low Anterior Resection Syndrome
Effect of Exercise on Bowel Function in Colorectal Cancer Survivors
The survival rate of colorectal cancer patients is increasing due to the development of medical technology. However, many colorectal cancer survivors (CRCs) have bowel dysfunction unlike other cancer survivors.
- Trial name
- NCT05420870
- Testing
- exercise
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Postoperative Ileus, Postoperative Nausea
Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function
Point-of-care gastric ultrasound will be used to measure stomach contents postoperative in patients who underwent colorectal surgery.
- Conditions
- Postoperative Ileus, Postoperative Nausea, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT04747691
- Testing
- Bedside gastric ultrasound
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eric Schwenk
Postoperative Ileus
Effect of Sugared Chewing Gum on Gastrointestinal Recovery After Major Colorectal Surgery
The Purpose of this study is to evaluate the effect of gum chewing on recovery of gastrointestinal function in patient undergoing major colorectal surgery.
- Trial name
- NCT01559662
- Testing
- Sugared Chewing Gum (Juicy Fruit)
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Cedars-Sinai Medical Center
Colorectal Cancer, Intraoperative Hemodynamic Management
MAP- Versus Cardiac Index-Guided Hemodynamic Management in Colorectal Surgery
This prospective randomized trial aims to compare the effects of two intraoperative hemodynamic management strategies on early postoperative renal function in patients undergoing colorectal surgery.
- Trial name
- NCT07609680
- Testing
- Mean Arterial Pressure-Guided Hemodynamic Management, Cardiac Index-Guided Hemodynamic Management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Constipation, Postoperative Care
Effectiveness of Squatting Position on Constipation Severity and Defecation Problems
One of the most common nursing care problems after surgery is defecation problems and the risk of constipation. The aim of the study was to determine the effectiveness of the squatting position with footstool on the constipation…
- Conditions
- Constipation, Postoperative Care, Nursing Care
- Trial name
- NCT05287789
- Testing
- Squatting position by footstool
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Meltem Kaya
Colorectal Neoplasms, Ileus Postoperative
The ACURE Trial: Acupuncture for Colorectal Recovery
Purpose: The goal of this clinical trial is to evaluate whether electroacupuncture (EA) can accelerate the recovery of bowel function in patients undergoing minimally invasive surgery for colorectal cancer.
- Conditions
- Colorectal Neoplasms, Ileus Postoperative, Postoperative Complication, Gastrointestinal Motility
- Trial name
- ACURE (NCT07496528)
- Testing
- Electroacupuncture (EA), Enhanced Recovery After Surgery (ERAS) Protocol
- Volunteers
- 240 people
- Sponsor
- Chang Gung Memorial Hospital
Rectal Cancer
Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE)
Primary hypothesis: Side-to-end anastomosis is non-inferior to colon J pouch for reconstruction after low anterior resection for rectal cancer in fecal incontinence (Wexner score).
- Trial name
- SAVE (NCT01006577)
- Testing
- side-to-end anastomosis, colon j pouch
- Where
- Germany
- Volunteers
- 306 people
- Sponsor
- Charite University, Berlin, Germany
Post-operative Pain
Efficacy of IV Acetaminophen for Pain Management
The investigators' goal in this planned prospective, randomized, patient blinded study is to compare our standard of care as the control group to an experimental group in which patients receive preemptive IV acetaminophen dosing…
- Trial name
- NCT02028715
- Testing
- IV acetaminophen
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Aultman Health Foundation
Gastric Cancer Patients Undergoing Laparoscopic Gastrectomy
The Effects of Intraoperative Dexmedetomidine Infusion on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
The investigators hypothesized that sympatholytic effect of dexmedetomidine would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery.
- Trial name
- NCT02164448
- Testing
- the dexmedetomidine group, the control group
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Yonsei University
Colon Cancer, Inflammatory Bowel Diseases
Functional Restoration After Abdominal and Pelvic Laparoscopic Surgery: Effect of Perioperative Intravenous Lidocaine
This is a blinded randomized controlled trial in patients undergoing laparoscopic colon surgery. The aim of this study is to assess whether perioperative intravenous lidocaine has an impact on the early post operative physical…
- Conditions
- Colon Cancer, Inflammatory Bowel Diseases, Diverticulitis
- Trial name
- NCT00982618
- Testing
- Lidocaine, Epidural Block, PCA Morphine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pain, Postoperative
Investigation of the Effect of Progressive Relaxation Exercises on Pain and Bowel Movements in Patients Undergoing Laparoscopic Cholecystectomy
The goal of this clinical trial is to compare in health conditions. The main questions it aims to answer are: Does progressive relaxation exercises reduce pain in patients undergoing laparoscopic cholecystectomy? Does progressive…
- Trial name
- NCT05969509
- Testing
- progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ataturk University
Short Bowel Syndrome
Specific Dietary Fibers May Enhance Colonic Adaptation in Short Bowel Syndrome Through Microbial and Metabolic Mechanisms That Drive Functional Compensation.
Ten patients with short intestines in clinical practice were intervened with dietary fiber. Serum and feces before and after the dietary fiber intervention were collected, and relevant indicators of nutrition and intestinal…
- Trial name
- NCT07186608
- Testing
- Dietary fiber intervention
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Jinling Hospital, China
Bladder Cancer, Ileus
Use of Pedometer Following Radical Cystectomy
This is a study to evaluate whether use of a pedometer following radical cystectomy decreases post-operative narcotic use and time to return of bowel function.
- Conditions
- Bladder Cancer, Ileus, Narcotic Use
- Trial name
- NCT04305730
- Testing
- Use of a pedometer following surgery, Standard of care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Benaroya Research Institute
Bowel Dysfunction, Postoperative Complications
Sugammadex To IMprove Bowel Function
Colon and rectal surgery is associated with high cost, long length of stay, high postoperative surgical site infection rate, high incidence of postoperative nausea and vomiting, and a high rate of hospital readmission.
- Conditions
- Bowel Dysfunction, Postoperative Complications, Neuromuscular Blockade
- Trial name
- STIM_Bowel (NCT04546672)
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Oregon Health and Science University