Clinical trials: Postoperative Cardiovascular Complication
Myocardial Injury After Non-Cardiac Surgery, Ischemia Reperfusion Injury
Differential Impact of Pringle and Portal Vein Occlusion on Myocardial Injury After Non-Cardiac Surgeries.
This study aims to investigate the impact of hepatic ischemia-reperfusion injury (HIRI) on the incidence of myocardial injury after non-cardiac surgery (MINS) and explore the potential underlying mechanisms.
- Trial name
- NCT06895798
- Where
- 2 sites in China
- Volunteers
- 1,286 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Atrial Fibrillation, Post-Op Complication
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG)…
- Trial name
- NCT06063538
- Testing
- CardiaMend in Combination with Amiodarone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Chicago
Myocardial Ischemic Reperfusion Injury, End Stage Heart Disease
Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation Surgery
The purpose of this study is to determine whether remote ischemic preconditioning with postconditioning (RIPC+RIPostC) reduces myocardial injury and improves clinical outcomes in heart transplantation surgery.
- Conditions
- Myocardial Ischemic Reperfusion Injury, End Stage Heart Disease, Heart Failure, Cardiomyopathy
- Trial name
- NCT02149316
- Testing
- RIPC+RIPostC, control
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Aortic Diseases, Cardiac Surgical Procedures
Selective Antegrade Cerebral Perfusion and Perioperative Optic Nerve Sheath Diameter in Ascending Aortic Surgery
In ascending aortic surgery the distal anastomosis may be constructed with the aortic cross-clamp maintained, or, where the extent of the aortic pathology and the geometry of the graft require it, after release of the cross-clamp…
- Conditions
- Aortic Diseases, Cardiac Surgical Procedures, Aortic Aneurysm, Thoracic, Delirium - Postoperative
- Trial name
- SACP-ONSD (NCT07800806)
- Testing
- Optic nerve sheath and optic nerve diameter ultrasonography, Transcranial Doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma
Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia
The aim of the study is to test the effectiveness and safety of the use of lidocaine infusion in multimodal analgesic management.
- Conditions
- Abdominal Aorta Aneurysm, Abdominal Aorta Atheroma, Surgery, Pain, Postoperative
- Trial name
- NCT04691726
- Testing
- lidocaine 10mg/ml, Metamizole, Morphine
- Where
- Poland
- Volunteers
- 87 people
- Sponsor
- Łukasz Krzych
Haemorrhoidal Disease, Post-operative Pain
Mesoglycan for Pain Control After Open Excisional HAEMOrrhoidectomy
Haemorrhoidal disease (HD) is the most common proctological disease, with a prevalence that can reach up to 39% of the population.
- Conditions
- Haemorrhoidal Disease, Post-operative Pain, Thrombosis
- Trial name
- MeHAEMO (NCT04481698)
- Testing
- Mesoglycan
- Where
- Italy
- Volunteers
- 398 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Patient Care Team, Coronary Artery Disease
Developing an Intervention to Improve the Non-Technical Skills of the Cardiac Surgical Teams
Teams of several medical professionals conduct high-risk cardiac surgical procedures. These professionals work in complex, stressful operating room environments requiring effective communication and teamwork skills.
- Conditions
- Patient Care Team, Coronary Artery Disease, Coronary Artery Bypass, Surgery
- Trial name
- NCT06257511
- Testing
- Simulation-Based Mastery Learning of the Non-technical skills
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Myocardial Reperfusion Injury, Treatment Outcome
Clinical Efficacy of Extracorporeal Cardiac Shock Wave Therapy in Patients With Ischemia-reperfusion Injury
This trial was a prospective, open-label, single-center, randomized trial, To observe the clinical efficacy of extracorporeal cardiac shock wave in the treatment of patients with myocardial ischemia-reperfusion injury and the…
- Conditions
- Myocardial Reperfusion Injury, Treatment Outcome, Prognosis, ST Elevation Myocardial Infarction
- Trial name
- CEECSWIRI (NCT05624203)
- Testing
- Extracorporeal cardiac shock wave therapy(ECSW)
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Peripheral Vascular Disease
Tele-Health Electronic Monitoring to Reduce Post Discharge Complications and Surgical Site Infections
Abstract: It is intuitive that post discharge surgical complications are associated with increased patient dissatisfaction, and directly associated with an increase in medical expenditures.
- Trial name
- THEM (NCT02767011)
- Testing
- Tele-Health Electronic Monitoring (THEM)
- Volunteers
- 30 people
- Sponsor
- CAMC Health System
Arrythmia, Chronic Pain
Acute and Chronic Pain After One-stage Hybrid Arrhythmia Ablation Surgery
After one-stage hybrid arrhythmia ablation surgery there are possible side effects like acute and chronic pain. There is a lot of research surrounding these pains but not specifically after one-stage hybrid arrhythmia ablation…
- Conditions
- Arrythmia, Chronic Pain, Acute Pain, Post Operative Pain
- Trial name
- NCT05211492
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 43 people
- Sponsor
- Universitair Ziekenhuis Brussel
Myocardial Ischemic Reperfusion Injury
Erythropoietin Effect on Ischemic_ Reperfusion Injury in Coronary Artery Bypass Graft Surgery
The aim of this trail is to assess the safety and therapeutic effects of single EPO intervention in different times during coronary surgery in changes of inflammatory response.
- Trial name
- NCT02984111
- Testing
- normal saline, erythropoietin
- Where
- Iran
- Volunteers
- 97 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
General Anesthesia
Multimodal Monitoring During General Anesthesia in ENT Surgery
This study evaluated whether using several monitoring methods together during general anesthesia could improve patient safety and help anesthesiologists adjust medication doses in adults undergoing ear, nose, and throat (ENT)…
- Trial name
- NCT07895836
- Testing
- Multimodal Anesthesia Monitoring (BIS, SPI, TOF), Standard Anesthesia Monitoring
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Barbara Verro
Acute Ischemic Stroke, Reperfusion Injury
Wet and Dry Biomarkers to Predict Secondary Injury in Stroke: From Bench to Bedside - The NIMBLE Study
Infarct growth (IG), Hemorrhagic Transformation (HT) and Cerebral Edema (CE) can be considered pivotal phenomena of clinical deterioration following an acute ischemic stroke.
- Conditions
- Acute Ischemic Stroke, Reperfusion Injury, Cerebral Edema, Hemorrhagic Transformation Due to Acute Stroke
- Trial name
- NIMBLE (NCT07422636)
- Where
- Italy
- Volunteers
- 213 people
- Sponsor
- University of Florence
Reperfusion Injury
Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecologic Laparoscopic Surgery
TEAS might protect against postoperative pulmonary such as ischemia-reperfusion injury (IRI) and atelectasis. We tested the hypothesis that transcutaneous electrical acupoint stimulation protects against postoperative pulmonary…
- Trial name
- NCT02850471
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Vascular Access Complication, Ultrasound Therapy; Complications
Ultrasound-Guided Vascular Puncture and Catheterization
To assess and improve the safety and success rate of vascular puncture and catheterization using ultrasound-guided methods.
- Conditions
- Vascular Access Complication, Ultrasound Therapy; Complications, Perioperative/Postoperative Complications, Cardiovascular Abnormalities
- Trial name
- UGVPC (NCT03656978)
- Testing
- dynamic, Regular-triangle
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Peking Union Medical College Hospital
Abdominal Aneurysm, Endovascular Aortic Repair
Pre-emptive Coil Embolization in Endovascular Aortic Repair
Abdominal aortic aneurysms are often treated with a minimally invasive procedure called endovascular aortic repair (EVAR). While EVAR is widely used, it can sometimes lead to complications over time, and some patients may require…
- Conditions
- Abdominal Aneurysm, Endovascular Aortic Repair, Endoleak
- Trial name
- PRIZE (NCT06975215)
- Testing
- Concomitant embolization, EVAR
- Volunteers
- 332 people
- Sponsor
- Uppsala University
Valvular Heart Disease
Impact of Perioperative Shedding of the Endothelial Glycocalyx on the Incidence of Postoperative Acute Kidney Injury in Patients Undergoing Valvular Heart Surgery.
Endothelial glycocalyx, the luminal structure of healthy vasculature, plays critical roles in regulation of inflammatory responses, vascular permeability, blood coagulation.
- Trial name
- NCT03197051
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Yonsei University
Postoperative Pain
Postoperative Pain and Tenesmus After Doppler-Guided Hemorrhoidal Artery Ligation With or Without Mucopexy
Hemorrhoidal disease is one of the most common anorectal disorders affecting adults worldwide. Doppler-guided hemorrhoidal artery ligation (HAL) is a minimally invasive surgical technique that has gained popularity because of its…
- Trial name
- NCT07710053
- Testing
- HAL + Mucopexy, HAL Alone
- Volunteers
- 150 people
- Sponsor
- Ali Genc
Transient Ischemic Attack, Acute Stroke
the Research of the Cerebral Protection Effects of Electroencephalogram (SedLine) During Carotid Endarterectomy
Fragile brain is the most common phenomenon seen in the patients undergoing CEA. The patients with fragile brain have a high incidence of postoperative brain dysfunction.
- Conditions
- Transient Ischemic Attack, Acute Stroke, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- NCT03622515
- Testing
- Anesthesia level and cerebral perfusion pressure
- Where
- 2 sites in China
- Volunteers
- 220 people
- Sponsor
- Beijing Municipal Administration of Hospitals
Traumatic Brain Injury, Trauma, Nervous System
Remote Ischemic Conditioning as a Treatment for Traumatic Brain Injury
The prevention of secondary brain injury is a primary goal in treating patients with severe traumatic brain injury (TBI). Secondary brain injury results from tissue ischemia induced by increased vascular resistance in the at-risk…
- Conditions
- Traumatic Brain Injury, Trauma, Nervous System, Reperfusion Injury, Ischemia, Brain
- Trial name
- NCT03176823
- Testing
- CellAegis Technologies autoRIC device, Best Practice Management of Traumatic Brain Injury
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Unity Health Toronto