Clinical trials: Postoperative Constipation
Rectal Cancer, Fecal Incontinence and Constipation
Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome
Low Anterior Resection Syndrome (LARS) is a common complication after sphincter-preserving rectal cancer surgery and may negatively affect bowel function and quality of life.
- Conditions
- Rectal Cancer, Fecal Incontinence and Constipation, Aerobic Exercise, Guided Imagery Exercise
- Trial name
- NCT07732894
- Testing
- Exercise, guided imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Constipation, Abdominal Surgery
Effect of Preoperative Abdominal Effleurage on Postoperative Constipation
This randomized controlled study aims to evaluate the effect of preoperative abdominal superficial effleurage training on the development of postoperative constipation in patients undergoing abdominal surgery.
- Conditions
- Constipation, Abdominal Surgery, Postoperative Constipation
- Trial name
- NCT07344532
- Testing
- Abdominal Superficial Effleurage Training
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ege University
Constipation, Surgical Treatment
To Explore the Efficacy and Safety of Surgical Treatment for Constipation, as Well as the Changes of Postoperative Intestinal Motility, Flora, Nutritional Status and Other Indicators
Chronic constipation is a heterogeneous disease with multiple symptoms, and its incidence is on the rise in many countries. It has become a common disease affecting the quality of life.
- Trial name
- NCT05983926
- Testing
- Subtotal colectomy was performed
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai 10th People's Hospital
Constipation, Lower Extremity Surgery
Ear Massage Effect on Bowel Activity After Surgery
Constipation is seen in patients undergoing orthopedic surgical interventions at rates as high as 23% to 94%. Constipation develops more frequently in individuals undergoing major orthopedic surgical interventions such as lower…
- Trial name
- NCT06862986
- Testing
- Ear massage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mersin University
Constipation
Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients
Constipation is a known complication of the postoperative period after spinal surgery, where prescription pain medicines called opioids are traditionally used in high doses for the treatment of surgery-related pain.
- Trial name
- NCT02946580
- Testing
- MOVANTIK™ (naloxegol), Sugar Pill
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Massachusetts General Hospital
Constipation
Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation
Patients requiring opioids for post-operative pain control following elective orthopedic procedures which has resulted in constipation symptoms, and who are in inpatient rehabilitation will be randomized to two different…
- Trial name
- NCT00662363
- Testing
- Lubiprostone, Senna
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Shirley Ryan AbilityLab
Postoperative Constipation, Pelvic Organ Prolapse Vaginal Surgery
Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior Repair
This study will determine if defecation posture, when using a defecation posture modification device (DPMD), improves ease with first bowel movement following pelvic reconstructive surgery, specifically posterior repair.
- Conditions
- Postoperative Constipation, Pelvic Organ Prolapse Vaginal Surgery, Defecation Function
- Trial name
- NCT06253689
- Testing
- Defecation Posture Modification Device
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- TriHealth Inc.
Constipation, Stool
The Effect of Preoperative Abdominal Massage on Postoperative Constipation
The aim of this clinical study is to determine whether preoperative abdominal massage has an effect on the development of postoperative constipation.
- Trial name
- NCT07570004
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Burcu Ozkan
Intestinal Flora, Anorectal Diseases
Research on the Efficacy and Mechanism of Shouhui Tongbian Capsules in Treating Postoperative Constipation of Benign Anal and Rectal Diseases Based on Gut Microbiota Analysis
The goal of this clinical trial is to evaluate whether Shouhui Tongbian Capsule can improve postoperative constipation in adults aged 18 to 75 years after surgery for benign anorectal diseases, including hemorrhoids and anal…
- Conditions
- Intestinal Flora, Anorectal Diseases, Surgery, Constipation
- Trial name
- NCT07648394
- Testing
- Shouhui Tongbian Capsules, Lactulose Oral Solution Control Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- China-Japan Friendship Hospital
Obesity &Amp; Overweight
The Impact of Probiotics on Bariatric Treatment Outcomes
The planned study aims to assess whether probiotics improve the quality of life in patients during the early postoperative period following sleeve gastrectomy, and whether they influence the absorption of micro- and…
- Trial name
- PROBE (NCT07258732)
- Testing
- Probiotic, Diet
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Postoperative Pain, Opioid Induced Constipation
A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy
Objectives: Primary objective: To demonstrate that the treatment with OXN PR tablets up to 72 hrs after surgery is superior to the treatment with OxyPR with regards to constipation in subjects with postoperative pain after…
- Trial name
- NCT01109511
- Testing
- naloxone, oxycodone
- Where
- Norway
- Volunteers
- 85 people
- Sponsor
- Ullevaal University Hospital
Postoperative Pain, Opioid Related Disorders
A Comparison of PR Oxycodone/Naloxone and PR Oxycodone After Cardiac Surgery
The aim of the study is to describe the effects of oxycodone/naloxone combination in comparison to oxycodone for the treatment of postoperative pain in patients undergoing cardiac surgery.
- Trial name
- NCT01374763
- Testing
- Oxycodone, Prolonged-release oxycodone/naloxone
- Where
- Finland
- Volunteers
- 165 people
- Sponsor
- Kati Järvelä
Postoperative Complications, Respiratory Depression
Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments
This study aims to evaluate the efficacy and safety of Remimazolam, either used alone or in combination with Propofol, for moderate sedation anesthesia during endoscopic therapies or examinations.
- Conditions
- Postoperative Complications, Respiratory Depression, Postoperative Nausea, Vomiting
- Trial name
- Remimazolam (NCT06777758)
- Testing
- Remimazolam, Propofol
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Low Anterior Resection Syndrome (LARS)
Evaluating the Optimal Timing of Trans-Anal Irrigation for Low Anterior Resection Syndrome Post-rectal Cancer Surgery
This study aims to evaluate the optimal timing of trans-anal irrigation (TAI) for participants with low anterior resection syndrome (LARS) who have undergone surgery for rectal cancer.
- Trial name
- EARLY-TAI (NCT07696689)
- Testing
- Water-based transanal irrigation system
- Volunteers
- 250 people
- Sponsor
- Simona Ascanelli
OIC
RELISTOR's Effects on Opioid-Induced Constipation
This will be a prospective case-control study of 40 patients undergoing 1-2 level ALIF procedures at Methodist Dallas Medical Center (MDMC).
- Trial name
- NCT04930237
- Testing
- Relistor Injectable Product, Docusate Calcium, Bisacodyl
- Where
- United States
- Sponsor
- Methodist Health System
Postoperative Pain, Nausea and Vomiting, Postoperative
Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks
The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control…
- Conditions
- Postoperative Pain, Nausea and Vomiting, Postoperative, Dizziness, Constipation
- Trial name
- Dex-Dex PNB (NCT07099222)
- Testing
- Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks, Ropivacaine with low, non weight based Dexamethasone additive
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Constipation
The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery
We are doing this study to see if using an over the counter mild laxative, SennaS, there is a difference in time required to have a bowel movement in women who are having surgery for prolapse (when your uterus and/or vagina drop…
- Trial name
- NCT00571896
- Testing
- Senna+ docusate
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Hartford Hospital
Constipation, Postoperative Care
Effectiveness of Squatting Position on Constipation Severity and Defecation Problems
One of the most common nursing care problems after surgery is defecation problems and the risk of constipation. The aim of the study was to determine the effectiveness of the squatting position with footstool on the constipation…
- Conditions
- Constipation, Postoperative Care, Nursing Care
- Trial name
- NCT05287789
- Testing
- Squatting position by footstool
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Meltem Kaya