Clinical trials: Postoperative Delirium
Postoperative Delirium, Type 2 Diabetes
Association of Preoperative Hippocampal Glucose Metabolism With Postoperative Delirium in Older Diabetic Patients
Objective: To investigate the association between preoperative hippocampal glucose metabolism levels and the risk of postoperative delirium (POD) in elderly patients with type 2 diabetes (T2DM), and to provide a prospective…
- Trial name
- NCT07369466
- Volunteers
- 154 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Pain
Postoperative Discomfort After Dental General Anesthesia
The aim of this prospective, randomised, controlled clinical trial was to compare immediate postoperative discomfort, emergence delirium and recovery time of the patients intubated using either laryngeal mask airway or…
- Trial name
- NCT03197753
- Testing
- Laryngeal mask airway, Nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Cardiac Surgery, Cardiopulmonary Bypass
Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery
Delirium is an acutely occurred and fluctuating cerebral dysfunction characterized with inattention, altered consciousness, cognitive decline and/or abnormal perception.
- Conditions
- Cardiac Surgery, Cardiopulmonary Bypass, Dexmedetomidine, Delirium
- Trial name
- NCT03624595
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 504 people
- Sponsor
- Dong-Xin Wang
Postoperative Delirium
The Preventive Effect of Different Doses of Intranasal Insulin on Postoperative Delirium
Postoperative delirium is one of the common complications in the older aldults after surgery, which can lead to longer hospita stay，memory loss and reduced quality of life. There is currently no specific treatment.
- Trial name
- NCT06443957
- Testing
- Intranasal normal saline, Intranasal insulin-20U, Intranasal insulin-40U
- Where
- China
- Volunteers
- 129 people
- Sponsor
- The First Hospital of Jilin University
Central Nervous System Diseases
Impact Dexmedetomidine on Postoperative Delirium in Patients After Intracranial Operation for Brain Tumor
Postoperative delirium is one of the most common serious complications after major surgery and is associated with undesirable consequences.
- Trial name
- NCT04494828
- Testing
- Dexmedetomidine, Normal saline group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Anesthesia, General
Maternal Voice on Anesthetic Emergence Period
Mother spend a large amount of time with their children. It is assumed that mother contributes to their neurological development not only with visual stimuli, but also with auditory stimuli.
- Trial name
- MatherVoice (NCT02860377)
- Testing
- recorded maternal voice, recorded stranger's voice
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Daegu Catholic University Medical Center
Delirium in Old Age, Anesthesia; Adverse Effect
Postoperative Dexmedetomidine in Prevention of Postoperative Delirium
The goal of this clinical trial is to learn how postoperative infusion of dexmedetomidine would influence postoperative delirium in elderly patients undergoing lung surgery. The main questions it aims to answer are : 1.
- Trial name
- NCT06382961
- Testing
- Dexmedetomidine injection, Sufentanil injection
- Where
- China
- Volunteers
- 287 people
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Postoperative Delirium
The Effect of Transcutaneous Electrical Acupoint Stimulation Combined With Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery
The aim of this clinical trial is to study the effect of transcutaneous electrical acupoint stimulation combined with auricular vagus nerve stimulation on postoperative delirium in elderly patients undergoing gastrointestinal…
- Trial name
- NCT07045090
- Testing
- Transcutaneous electrical acupoint stimulation, Transcutaneous electrical acupoint stimulation combined with auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Affiliated Hospital of Nantong University
Postoperative Delirium
Incidence of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery
Postoperative delirium (POD) is the most common adverse neurologic complication that can occur in patients of any age. Its incidence varies across age groups and is substantially influenced by patient-related risk factors.
- Trial name
- NCT04707794
- Testing
- Sevoflurane, Desflurane
- Where
- 2 sites in India
- Volunteers
- 270 people
- Sponsor
- Sir Ganga Ram Hospital
Cognitive Impairment, Frail Elderly Syndrome
Cognition and the Immunology of Postoperative Outcomes
This research will test the hypothesis that immune system disequilibrium / dysfunction explains why preoperative cognitive impairment is a strong predictor of postoperative morbidity in older surgical patients.
- Conditions
- Cognitive Impairment, Frail Elderly Syndrome, Delirium, Surgery
- Trial name
- NCT04792983
- Testing
- No intervention
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Brigham and Women's Hospital
Delirium - Postoperative, Agitation
Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac Surgery
The goal of this clinical trial is to learn if a novel device (MindfulGarden) is beneficial in a population of patients undergoing cardiac surgery.
- Conditions
- Delirium - Postoperative, Agitation, Anxiety, Cardiac Surgery Recovery
- Trial name
- RESPITE (NCT07051096)
- Testing
- A novel device developed providing nature-driven responsive imagery that responds to the patient's physiological to distract, engage, and de-escalate behaviours of delirium., Routine post-operative management and standard delirium reduction measures.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Delirium, Anesthesia Awareness
Anesthesia Depth Increases Delirium Incidence
This study aimed to determine whether targeting bispectral index (BIS) readings of 55 (light anaesthesia) was associated with a lower incidence of delirium, dementia (POD), POCD and mortality but higher rates of awareness and…
- Trial name
- NCT05656703
- Testing
- BIS guidance of anesthesia, Standard of Care
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Heidelberg University
Hearing Loss, Hearing Loss, Age-Related
Sight and Hearing Investigation Into Effects on Delirium
The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: Are hearing and vision loss related to increased risk of having delirium? Do…
- Conditions
- Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium
- Trial name
- SHIELD (NCT06176625)
- Testing
- Communication Signage, Amplifier Use
- Where
- United States
- Volunteers
- 1,543 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Delirium
Assessment of Postoperative Delirium With CAM ICU Score in Patients Treated With Serotoninergic Reuptake (SSRI) Inhibitors and Undergoing Intervention of Heart Surgery on Pump
The study aims to observe the presence of postoperative delirium in patients undergoing elective cardiac surgery, without changing the pharmacological prescriptions of the enrolled patients and the procedures carried out by…
- Trial name
- DeCAMS-ON (NCT05089097)
- Testing
- evaluation of delirium with CAM-ICU Score
- Where
- Italy
- Volunteers
- 152 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Delirium in Old Age, Sleep Disturbance
Sleep & Postoperative Delirium in Hispanic/ Latino Patients After Cardiothoracic Surgery
The purpose of this research is to study pre-operative sleep problems and delirium in Hispanic/Latino patients after heart and lung surgery.
- Conditions
- Delirium in Old Age, Sleep Disturbance, Circadian Rhythm Sleep Disorder
- Trial name
- NCT04786899
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Miami
Frailty
Correlation Between Modified Weakness Index and Postoperative Delirium in Elderly Patients
1. To study whether there is a correlation between weakness and postoperative delusions in elderly non-cardiac surgery patients 2. Can the improved debilitating index predict the delusion after non-cardiac surgery 3.
- Trial name
- NCT05189678
- Testing
- No intervention
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Qianfoshan Hospital
Neurological Injury, Stroke
Carbon Dioxide Surgical Field Flooding and Aortic No-touch Off-pump Coronary Artery Bypass Grafting to Reduce Neurological Injuries After Surgical Coronary Revascularization (CANON): a Randomised, Controlled, Investigator and Patient Blinded Single Center Superiority Trial With Three Parallel Arms.
The objective of this study is to investigate the value of employing the aortic no-touch off-pump coronary artery bypass technique and the practice of carbon dioxide surgical field flooding for the prevention of type 1 and 2…
- Conditions
- Neurological Injury, Stroke, Postoperative Cognitive Dysfunction, Postoperative Delirium
- Trial name
- CANON (NCT03074604)
- Testing
- aortic no-touch OPCABG, OPCABG with partial clamp applying carbon dioxide, OPCABG with partial clamp
- Where
- Poland
- Volunteers
- 192 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Postoperative Delirium
Prevention of Postoperative Delirium After Acute Surgery
The aim of this trial is to evaluate the implementation and effect of an evidence based, multicomponent intervention on postoperative delirium, when fast implemented throughout the patients stay in hospital before, during and…
- Trial name
- POD-CARE (NCT04857125)
- Testing
- Patient interventions, Staff education
- Where
- Denmark
- Volunteers
- 476 people
- Sponsor
- Bispebjerg Hospital
Delirium
Postoperative Delirium in Cardiac Surgery ICU
Postoperative Delirium (POD) is a common complication in patients after cardiac surgery, which is associated with short-term prognosis and long-term quality of life.
- Trial name
- NCT04527341
- Volunteers
- 500 people
- Sponsor
- Shanghai Zhongshan Hospital
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University