Clinical trials: Postoperative Hypothermia, open to volunteers
Perioperative Hypothermia
Effect of Prewarming Duration on Blood Flow After Colon Resection Surgery
This study will examine whether warming patients before colon resection surgery improves blood flow in the fingers during early recovery from general anesthesia. It will also compare two warming durations.
- Trial name
- NCT07857538
- Testing
- Preoperative Forced-Air Warming
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Çiğdem Ünal Kantekin
Cardiac Arrest, Post Cardiac Arrest Syndrome
Lung-cOnservative Liquid VEntilation for the Induction of Ultra-Rapid COOLing After Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) affects over 356,000 individuals annually in the United States, with fewer than 10% surviving to hospital discharge, mirroring statistics from Europe.
- Trial name
- OverCool (NCT06798818)
- Testing
- Ultra-rapid therapeutic hypothermia induction by total liquid ventilation
- Where
- France
- Volunteers
- 24 people
- Sponsor
- ORIXHA
Shivering, Postoperative Shivering
Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic Surgeries
Shivering is a common and distressing complication following spinal anesthesia, affecting up to 70% of patients. It significantly increases oxygen consumption, places stress on the cardiovascular system, and interferes with…
- Conditions
- Shivering, Postoperative Shivering, Hypothermia
- Trial name
- NCT07855575
- Testing
- Paracetamol 2 g, Paracetamol 1 g
- Volunteers
- 150 people
- Sponsor
- Assiut University
Out-of-hospital Cardiac Arrest (OHCA), ECMO Treatment
Hypothermia Versus Normothermia After Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital Cardiac Arrest
The SAVE-J NEUROTHERM trial is a cluster randomized trial that evaluated and compared the mortality risk, neurological outcomes, and adverse events between patients who underwent hypothermia and those who underwent normothermia…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), ECMO Treatment, Temperature, Post Cardiac Arrest Syndrome
- Trial name
- J-NEURO (NCT06776549)
- Testing
- Temperature control
- Where
- 29 sites in Japan
- Volunteers
- 468 people
- Sponsor
- Kagawa University
Abdominal Surgery Complications, Hypothermia Following Anesthesia
The Effect of Heating the Intensive Care Room in the Early Postoperative Period on Patient Outcomes
The aim of this study was to evaluate the effect of heating the intensive care room in the early postoperative period on patient outcomes.
- Trial name
- NCT07137143
- Testing
- The rooms of the intervention group patients will be heated before they come to intensive care and the temperature of the room will be increased.
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Cukurova University
Liver Transplant, Liver Failure
Hypothermic Machine Perfusion for Liver Graft Preservation
The goal of this clinical trial is to evaluate whether hypothermic machine perfusion improves liver graft preservation and post-transplant outcomes compared to conventional static cold storage in adult patients undergoing liver…
- Trial name
- HOPE-Liver (NCT07595627)
- Testing
- Hypothermic Machine Perfusion, Static Cold Storage
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Hepatocellular Carcinoma, Liver Transplant; Complications
Impact of Graft Reconditioning With Hypothermic Machine Perfusion on HCC Recurrence After Liver Transplantation
The use of devices for liver grafts perfusion before transplantation, either hypothermic (HOPE) or normothermic (NMP), is rapidly spreading thanks to the promising results obtained so far in terms of graft survival and…
- Trial name
- NCT06236568
- Testing
- D-HOPE machine perfusion, Liver transplantation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Myocardial Infarction, ST-Elevation Myocardial Infarction (STEMI)
Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction.
Acute myocardial infarction with ST segment elevation is often accompanied by a totally occluded coronary artery. Which has deleterious effects on heart muscle.
- Conditions
- Myocardial Infarction, ST-Elevation Myocardial Infarction (STEMI), Reperfusion Injury, Microvascular Occlusion
- Trial name
- NCT06567249
- Testing
- Intracoronary hypothermia, Standard percutaneous coronary intervention
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Stroke, Acute Ischemic Stroke
Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy (COOLHEAD-2b)
COOLHEAD-2b is a multicentre, phase 2, prospective, randomised, controlled, open-label, blinded-endpoint trial evaluating the safety and efficacy of non-invasive convective head cooling as an adjunct to endovascular thrombectomy…
- Conditions
- Stroke, Acute Ischemic Stroke, Brain Ischemia, Ischaemic Stroke
- Trial name
- COOLHEAD-2B (NCT07526649)
- Testing
- Non-invasive convective head cooling, Standard of Care (SOC)
- Where
- New Zealand
- Volunteers
- 182 people
- Sponsor
- Auckland City Hospital
Nephrectomy / Methods, Intraoperative Hypothermia
Effect of Preoperative Prewarming on Serum Lactate Levels in Patients Undergoing Elective Nephrectomy
The goal of this observational study is to learn whether warming patients before surgery, called "prewarming," affects blood lactate levels (a marker of how well tissues are getting oxygen) and recovery in adults having planned…
- Conditions
- Nephrectomy / Methods, Intraoperative Hypothermia, Hyperlactatemia
- Trial name
- NCT07702487
- Testing
- Preoperative active warming (prewarming)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Beyzanur Aydoğdu
Liver Transplantation (LT), Early Allograft Dysfunction
New Biomarkers for Organ Viability Assessment During Hypothermic Machine Perfusion in Liver Transplantation: the Role of Extemporaneous Histological Examination.
Liver transplantation is a life-saving treatment for patients with severe liver disease. Because of the shortage of donor organs, transplant centers increasingly use donor livers that may be more vulnerable to injury and…
- Conditions
- Liver Transplantation (LT), Early Allograft Dysfunction, Primary Non-function, Ischemia-Reperfusion Injury
- Trial name
- LOVE (NCT07674394)
- Testing
- Hypothermic Oxygenated Machine Perfusion (HOPE/D-HOPE)
- Where
- 3 sites in Italy
- Volunteers
- 150 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Perioperative Hypothermia, Hernia, Inguinal
Effect of Laryngeal Mask Airway vs Endotracheal Tube on Hypothermia in Laparoscopic Hernia Surgery
This study aims to compare the effects of a laryngeal mask airway (i-gel) and an endotracheal tube on perioperative hypothermia in patients undergoing laparoscopic inguinal hernia surgery.
- Trial name
- LMA-HYPOTH (NCT07913841)
- Testing
- i-gel Supraglottic Airway Device, Endotracheal Tube
- Volunteers
- 256 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Cancer Surgery, Intraoperative Hypothermia
Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival
Intraoperative hypothermia is common in patients having major surgery and the compliance with intraoperative temperature monitoring and management remains poor.
- Conditions
- Cancer Surgery, Intraoperative Hypothermia, Targeted Temperature Management, Postoperative Delirium
- Trial name
- NCT06256354
- Testing
- Routine thermal management, Target temperature management
- Where
- 36 sites in China
- Volunteers
- 3,992 people
- Sponsor
- Peking University First Hospital
Hypothermia, Shivering
Effect Of Acupressure On Hypothermıa And Shıverıng After Cesarean Sectıon
This research was planned to determine the effect of acupressure on hypothermia and shivering after cesarean section. H01: There is no difference in hypothermia findings between women who received acupressure and women in the…
- Conditions
- Hypothermia, Shivering, Postoperative Hypothermia, Postoperative Shivering
- Trial name
- NCT07864376
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Hypothermia Following Anesthesia
Study of the Prevalence of Postoperative Hypothermia in Adults Undergoing Non-Cardiac Surgery in Spanish Post-Anesthesia Care Units
The prevalence of Hypothermia in Spanish Post-Anesthesia Recovery Units (in Spanish: "Prevalencia de Hipotermia en las Reanimaciones Españolas" PHRES Study) is a prospective, multicenter observational study that will evaluate how…
- Trial name
- PHRES (NCT07839728)
- Testing
- Postoperative temperature monitoring
- Where
- Spain
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Caesarean Section
Maternal Hypothermia After Caesarean Section - Implications for Postoperative Recovery
The aim of the study is to assess patient reported outcomes after caesarean section using self report questionnaire.
- Trial name
- NCT07244354
- Testing
- Self report questionnaire
- Where
- Norway
- Volunteers
- 700 people
- Sponsor
- Oslo University Hospital
Perioperative Hypothermia, Inadvertent Perioperative Hypothermia
Resistive Versus Forced-Air Warming for Prevention of Perioperative Hypothermia
Perioperative hypothermia (core temperature below 36.0 °C) is a common complication of surgery and is associated with increased blood loss, wound infection, cardiovascular events and patient discomfort.
- Conditions
- Perioperative Hypothermia, Inadvertent Perioperative Hypothermia, Hypothermia
- Trial name
- WARM-NI (NCT07909252)
- Testing
- Forced-air warming, Resistive conductive warming
- Where
- Czechia
- Volunteers
- 680 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.