Clinical trials: Postoperative Infection of Incision
Surgical Site Infection, Antibiotic Prophylaxis
The Role of Guideline-adherent Perioperative Antibiotic Administration and the Risk of Surgical Site Infections After Non-cardiac Surgery.
This study will seek to describe current practice of antibiotic prophylaxis to identify the effect of appropriate perioperative antimicrobial coverage - specifically regarding timing, dose adjustments, and redosing - on surgical…
- Trial name
- NCT03982810
- Testing
- Antibiotics
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Surgical Wound Infection
Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis
Routine antibiotics for the intravenous and oral prophylaxis of colorectal surgery will be used. Experimental group: Patients undergoing elective colorectal surgery that involves, colonic resection.
- Trial name
- ORALEV (NCT02505581)
- Testing
- Extra dosage - cefuroxime (750mg) I.V, Colorectal Surgery, Ciprofloxacin 750 mg oral
- Where
- 3 sites in Spain
- Volunteers
- 536 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Surgical Wound Infection, Vascular Surgery
Supplemental Oxygen in Vascular Surgery
The purpose of this study was to test the hypothesis that supplemental postoperative oxygen reduces the risk of surgical wound infection in patients following lower limb vascular surgery.
- Trial name
- NCT00873704
- Testing
- supplemental postoperative oxygen
- Where
- 6 sites in Finland
- Volunteers
- 274 people
- Sponsor
- North Karelia Central Hospital
Surgical Wound Infection
Recolonization Following Preoperative Disinfection Plastic Adhesive Drapes
The purpose of this study is to measure the time to recolonization intraoperatively after preoperative disinfection with chlorhexidine solution in ethanol and to determine evidence of differential bacterial growth with or without…
- Trial name
- NCT01316588
- Testing
- Plastic adesive drape, Microbial Sealant
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Örebro University, Sweden
Surgical Site Infection, Patient Satisfaction
Effect of Surgical Site Infections on Patient Reported Cosmetic Outcomes in Dermatologic Surgery
This study involves surveying two matched groups of patients that underwent dermatologic surgery at our department. One group had a documented surgical site infection and the other didn't.
- Trial name
- NCT04744961
- Testing
- SCAR-Q survey
- Where
- Sweden
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Region Skane
Post Operative Wound Infection, Suture
No Closure vs Interrupted vs Continuous Subcutaneous Closure: Operative Time and Wound Outcomes
The goal of this clinical trial is to research whether different methods of suturing during elective cesarean delivery affect surgery time and early wound healing.
- Conditions
- Post Operative Wound Infection, Suture, Suture Techniques, Ceserean Section
- Trial name
- NCT07451275
- Testing
- Suture technique, Interrupted closure (3 sutures), Suture technique, Continuous non-locking closure
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Yuzuncu Yil University
Surgical Wound Infection
Prevention of Surgical Site Infections
The primary research question is whether interventions to prevent caregiver and system errors will increase the proportion of laparotomy patients who receive recommended measures to prevent surgical site infections.
- Trial name
- NCT00353613
- Testing
- Package of targeted interventions to reduce error
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- The University of Texas Health Science Center, Houston
Staphylococcal Aureus Infection, Surgical Site Infection (SSI)
Gene Expression Analysis of Biofilm Formation and Antimicrobial Resistance in Clinical Methicillin-Resistant Staphylococcus Aureus
Staphylococcus aureus are Gram-positive cocci that asymptomatically colonize the skin and mucosal surfaces of approximately 20-30% of healthy individuals . Although they commonly exist as a harmless commensal organisms, S.
- Trial name
- NCT07796555
- Testing
- swab from lesion, Biochemical reactions, Antibiotic sensitivity
- Volunteers
- 100 people
- Sponsor
- Sohag University
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- PHOMIC (NCT04067843)
- Testing
- Photodynamic treatment
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Operation Wound; Infection, Bacterial Infections
Nudging Effect of Timer on Surgical Rub
To study whether a device has a nudging effect on the time spend on surgical rub.
- Conditions
- Operation Wound; Infection, Bacterial Infections, Surgical Procedure, Unspecified
- Trial name
- NCT04609384
- Testing
- Alcohol rub timer device
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Sygehus Lillebaelt
Surgery, Surgical Site Infection
Intraoperative Hygiene Measures and Surgical Site Infections
Surgical site infections are associated with high morbidity and cost Hypothesis: Extended intraoperative hygiene measures decrease surgical site infections in general surgery compared to standard hygiene measures.
- Conditions
- Surgery, Surgical Site Infection, Hygiene, Discipline
- Trial name
- NCT00555815
- Where
- Switzerland
- Volunteers
- 1,032 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Complications
The Effect of Telephone Nursing Education and Counseling Services Given to Satisfaction Level and Self-Care Strength
In the post-discharge period, it is important to follow the patients from home by telephone and to provide the necessary nursing education and counseling services, increasing the self-care powers of the patients, increasing their…
- Trial name
- NCT05487638
- Testing
- Nursing Education and Counseling Service Provided to Patients by Video Calling on the Phone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Esophageal Cancer, Postoperative Pulmonary Atelectasis
High Flow Nasal Cannula After Esophagectomy
This study will compare the effect of HFNC versus standard oxygen administration after elective esophagectomy for cancer.
- Conditions
- Esophageal Cancer, Postoperative Pulmonary Atelectasis, Postoperative Pneumonia, Postoperative Pneumothorax
- Trial name
- OSSIGENA1V (NCT05718284)
- Testing
- AIRVO2, STANDARD CARE
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- Cristian Deana
Surgical Wound Infection, Hematoma
Comparing Outcomes Of Single Layer Versus Multilayer Leg Closure Techniques Following Great Saphenous Vein Harvesting For CABG
This study aims to address the knowledge gap by comparing the outcomes of single-layer and multi-layer leg closure techniques following great saphenous vein harvesting for Coronary artery bypass grafting. Research question: 1.
- Conditions
- Surgical Wound Infection, Hematoma, Seroma Following Procedure, Prolonged Hospital Stay
- Trial name
- CABG (NCT07355452)
- Testing
- Multi-layer closure (MLC), singlelayer closure for leg wound
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Surgical Wound Infection
Surgical Site Infections at a West Cameroon Hospital
Surgical site infections (SSI) constitute an important health concern in low and middle income countries, leading to prolonged hospital stay and increased costs.
- Trial name
- SSI Mbouo (NCT05018884)
- Testing
- Observation of surgical site infections
- Where
- Cameroon
- Volunteers
- 148 people
- Sponsor
- Christian Doll
Postoperative Hernia
Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR)
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Trial name
- (PROTOP-PAR) (NCT05508152)
- Testing
- Wound irrigation with amoxicillin-clavulanate in saline solution, Wound irrigation with a saline solution
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital de Granollers
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Colorectal Cancer, Lung Cancer
The Effects of Preoperative Bevacizumab on Perioperative Complications
This is a nationwide multicenter,retrospective,observational real-world study. 1. To assess the risk of perioperative complications in patients with tumor who received bevacizumab prior to unexpected operation. 2.
- Conditions
- Colorectal Cancer, Lung Cancer, Operation Wound; Infection, Bevacizumab
- Trial name
- NCT04788381
- Testing
- Bevacizumab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine