Clinical trials: Postoperative Insomnia, active
Hip Fractures
Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality
1. Eligible patients are randomly divided into experimental and control groups； 2. The experimental group is given esketamine combined with dexmedetomidine，while the control group is given normal saline； 3.
- Trial name
- NCT07002723
- Testing
- Esketamine combined with dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University Shenzhen Hospital
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients
Hip and knee replacement surgery is commonly performed in older adults. After surgery, many patients experience pain, limited movement, and sleep problems.
- Trial name
- NCT07354542
- Testing
- Virtual Reality-Based Relaxation, Traditional Relaxation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Laparoscopic Cholecystectomy, Postoperative Quality of Recovery
Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is one of the most commonly performed abdominal surgical procedures worldwide. Although the widespread implementation of Enhanced Recovery after Surgery (ERAS) protocols has improved perioperative…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Quality of Recovery, Preoperative Anxiety, Postoperative Sleep Quality
- Trial name
- MEL-REC (NCT07553143)
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine)
- Where
- Bangladesh
- Volunteers
- 84 people
- Sponsor
- Armed Forces Medical Institute Bangladesh
Dental, Dental Extraction
Insomnia and Post-Dental Surgery Pain: A Prospective Study
The purpose of this prospective observational study is to evaluate the relationship between preoperative sleep disturbances-specifically insomnia-and postoperative pain intensity following oral surgical procedures.
- Conditions
- Dental, Dental Extraction, Insomnia
- Trial name
- INDOLC (NCT07712432)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Osteoarthritis, Knee, Osteoarthritis, Hip
Promoting Sleep to Alleviate Pain - Arthroplasty
PROSAP-A is a perioperative randomized, controlled trial with a 12-month follow-up period after total knee arthroplasty (TKA) or total hip arthroplasty (THA), aiming to investigate both acute and long-term postoperative effects…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Insomnia, Surgery
- Trial name
- PROSAP-A (NCT06145516)
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I), Sleep education therapy (SET)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University
Immune-Nutritional Indexes (PNI, HALP), Postoperative Sleep Quality
Immune-Nutritional Scores and Sleep Quality After Total Abdominal Hysterectomy
This prospective observational study aims to evaluate the relationship between preoperative immune-nutritional status and postoperative sleep quality in women undergoing total abdominal hysterectomy under general anesthesia.
- Trial name
- NCT07038564
- Testing
- Immune-Nutritional Scoring and Postoperative Sleep Assessment
- Volunteers
- 60 people
- Sponsor
- Istinye University
Postoperative Sleep Disturbance, Thoracoscopic Surgery
Lemborexant on Perioperative Sleep Quality in Patients Undergoing Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is the mainstream minimally invasive procedure in thoracic surgery; However, the high-stress state during the perioperative period and severe postoperative pain often lead to…
- Trial name
- NCT07811401
- Testing
- Lemborexant 5 mg
- Volunteers
- 130 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Sleep Quality, Postoperative Behaviour
Sleep Quality - Comparing the Effect of Ondansetron or Dexamethasone Given as Routine Prophylaxis Intraoperatively to Prevent Post Operative Nausea and Vomiting (SCORPION)
Nausea and vomiting are common complications after anaesthesia, and anaesthetists routinely give medications to prevent them. Dexamethasone and ondansetron are the two most commonly used agents and have a long safety record.
- Conditions
- Postoperative Sleep Quality, Postoperative Behaviour, Postoperative Recovery in Children, Postoperative Nausea and Vomiting (PONV)
- Trial name
- SCORPION (NCT07777276)
- Testing
- Dexamethasone (IV), Ondansetron iv
- Where
- 3 sites in Australia, Brazil
- Volunteers
- 500 people
- Sponsor
- Telethon Kids Institute
Orthognathic Surgery, Malocclusions
Evaluation of Emotional Responses Using the I-Motions System and Self-assessment Questionnaires, and Assessment of Postoperative Anatomical and Structural Units (TMJ and Masticatory Muscles) in Orthognathic Surgery Patients
Orthognathic surgery is a surgical procedure involving one or both jaws to correct skeletal discrepancies, restore proper occlusion, and improve facial aesthetics.
- Conditions
- Orthognathic Surgery, Malocclusions, Jaw Abnormalities, Dentofacial Deformities
- Trial name
- NCT07477873
- Testing
- Observational Assessment
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Pain, Postoperative, Sleep
Effect of Foot Bath on Pain, Sleep, and Comfort Levels After Abdominal Surgery
The aim of this study was to investigate the effects of foot bath application on pain level, comfort and sleep quality in the postoperative period. H1: Foot baths have a postoperative pain-reducing effect.
- Trial name
- NCT07366567
- Testing
- Foot bath device
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Trakya University
Rotator Cuff Injuries, Postoperative Pain
Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair
The goal of this clinical study is to learn if using a special pillow placed behind the shoulder can help to reduce pain and improve sleep for patients after surgery to repair a torn rotator cuff.
- Conditions
- Rotator Cuff Injuries, Postoperative Pain, Sleep Quality
- Trial name
- NCT07372222
- Testing
- Posterior Shoulder Pillow, Conventional Rehabilitation Protocol
- Volunteers
- 126 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease, Sleep Quality
Effect of Eye Mask Use on Sleep Quality and Delirium After CABG Surgery
Coronary artery bypass graft (CABG) surgery is an effective treatment for coronary artery disease; however, sleep disturbances and delirium are common during the postoperative period and may adversely affect recovery.
- Conditions
- Coronary Artery Disease, Sleep Quality, Postoperative Delirium (POD)
- Trial name
- EYE-CABG (NCT07768020)
- Testing
- Eye Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Munzur University
Surgery, Pain
Perioperative Sleep Quality and Postoperative Pain Outcomes
This is a prospective, observational cohort study that will examine how sleep quality impacts postoperative pain and opioid consumption for pediatric patients.
- Conditions
- Surgery, Pain, Sleep, Spinal Fusion
- Trial name
- NCT06054802
- Testing
- eCAP
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Grant Heydinger
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Breast Cancer Related Lymphedema
Investigation of the Effects of Complex Decongestive Physiotherapy on Sleep Quality and Quality of Life in Women With Breast Cancer Related Lymphedema
Breast cancer is the most common type of cancer among women globally and has the highest mortality rate. Surgical interventions are typically required in the treatment of breast cancer, but these procedures can lead to…
- Trial name
- NCT06697158
- Testing
- Physiotherapy and rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Abant Izzet Baysal University
Sleep Quality Post-TKA, Postoperative Knee Function
Doxepin Alone or Combined With Ramelteon Versus Placebo for Improving Sleep Quality After Primary Total Knee Arthroplasty
Many patients experience poor sleep during recovery after total knee arthroplasty (TKA). Disturbed sleep can last weeks to months and may worsen pain, slow healing, and reduce overall quality of life.
- Conditions
- Sleep Quality Post-TKA, Postoperative Knee Function, Quality of Life After Primary TKA
- Trial name
- NCT07598734
- Testing
- Doxepin 6 mg, Ramelteon 8 mg
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Washington
Chronic Post-Surgical Pain
Effect of Perioperative Sleep Quality on Chronic Post-Surgical Pain
The goal of this prospective observational cohort study is to assess the impact of perioperative sleep quality on the development of chronic post-surgical pain (CPSP) in adult patients (aged 18-80 years, ASA I-III) undergoing…
- Trial name
- NCT06871891
- Where
- China
- Volunteers
- 1,138 people
- Sponsor
- Peking Union Medical College Hospital
Thoracic Surgical Procedures
Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. Three hundred-sixty adult patients undergoing elective thoracoscopic surgery will be randomly allocated at a 1:1 ratio to receive either intraoperative…
- Trial name
- NCT07794982
- Testing
- sodium oxybate
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jingsheng Lou
Colorectal Cancer, Sleep Quality
Association of Sleep Quality and Mental Status With Early Recurrence and Prognosis of Colorectal Cancer
This is a prospective observational cohort study to explore the effects of sleep quality and mental status on early postoperative recurrence and prognosis in patients with colorectal cancer.
- Conditions
- Colorectal Cancer, Sleep Quality, Mental Status Change
- Trial name
- NCT06443996
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ma Yanlei
Delirium - Postoperative, Cardiac Surgery
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium.
- Conditions
- Delirium - Postoperative, Cardiac Surgery, Cardiac Surgery Subjects, Orexin Antagonist
- Trial name
- PROTEX (NCT06648681)
- Testing
- Lemborexant 5 mg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia