Clinical trials: Postoperative Morbidity
Dementia, Postoperative Delirium (POD)
Prediction and Prevention of Postoperative Mortality and Morbidity
This study will contribute to creating a prospective and automated preoperative risk assessment algorithm for predicting 30-day mortality, major adverse cardiac and cerebrovascular events (MACCE), and postoperative neurocognitive…
- Conditions
- Dementia, Postoperative Delirium (POD), Postoperative Neurocognitive Disorder, Major Adverse Cardiac and Cerebrovascular Events
- Trial name
- NCT06042413
- Testing
- Personalized CPC Prehabilitation, Cognitive Training, Meditation
- Where
- 5 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of Pittsburgh
Obesity, Bariatric Surgery Candidate
Multi-Strategy Intervention for Anesthesia Care of Obese Patients A Factorial Randomized Controlled Trial
The main objective of this study is to investigate the optimal anesthesia for obese patients undergoing bariatric surgery in the strategies of positive pulmonary ventilation, tracheal intubation technique, hemodynamic monitoring…
- Conditions
- Obesity, Bariatric Surgery Candidate, Tracheal Intubation Morbidity, Nausea and Vomiting, Postoperative
- Trial name
- NCT05016076
- Testing
- Dexamethasone 8 mg, Applied inspiratory pressure (10, 15, 20, or 25 cmH2O), Tracheal intubation using video intubating stylet, video laryngoscopy, or direct laryngoscopy
- Where
- Taiwan
- Sponsor
- YingHsuanTai
Postoperative Complications
Prospective Biomechanical Analysis of Donor-site Morbidity Following Microvascular Fibula Transplantation
Pre- and postoperatively patients who underwent free fibula flap were examined regarding donor-site morbidity of the lower extremities.
- Trial name
- NCT02265991
- Testing
- Fibula Explantation
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postoperative Morbidity
Effects of Hyaluronic Acid Complex and Dexamethasone on Pain, Swelling, and Trismus After Mandibular Third Molar Surgery
This study aimed to comparatively evaluate the effects of a hyaluronic acid complex and dexamethasone on postoperative pain, swelling, and trismus following mandibular third molar surgery, compared with a control group.
- Trial name
- NCT07853196
- Testing
- Hyaluronic Acid Complex, Dexamethasone, Absorbable Hemostatic Gelatin Sponge (SPONGOSTAN™ Dental)
- Where
- Cyprus
- Volunteers
- 45 people
- Sponsor
- Cyprus Health and Social Sciences University
Postoperative Residual Curarization
Muscle Relaxants and Post-Anesthesia Complications
This Germany-wide, multi-center, epidemiologic study is designed to evaluate the incidence of post-operative/anesthesia effects of muscle relaxants (i.e.
- Trial name
- PORC (NCT00753389)
- Testing
- None (anesthesia)
- Where
- Germany
- Volunteers
- 20,000 people
- Sponsor
- Technical University of Munich
Colorectal Disorders, Regional Anesthesia Morbidity
Transversus Abdominis Plane Blocks With and Without Dexamethasone
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
- Conditions
- Colorectal Disorders, Regional Anesthesia Morbidity, Analgesia, Local Anesthetic Complication
- Trial name
- TAP-DEX (NCT05432934)
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Laparoscopic Surgery, Tracheal Intubation Morbidity
Effect of Cuff Pressure of Endotracheal Tube on POST
The main objective of this study is to evaluate the association between the duration of intraoperative cuff overpressure and the development of postoperative sore throat.
- Conditions
- Laparoscopic Surgery, Tracheal Intubation Morbidity, Sore-throat
- Trial name
- NCT05542823
- Where
- 2 sites in South Korea
- Volunteers
- 337 people
- Sponsor
- Seoul National University Hospital
Inflammation, Aortic Valve Stenosis
Is Monocyte/HDL Ratio a Predictor of Mortality in Aortic Valve Surgery
In this study, the investigators aimed to determine whether the preoperative Monocyte/HDL ratio would be a predictor of postoperative mortality and morbidity in patients who underwent aortic valve replacement due to aortic…
- Conditions
- Inflammation, Aortic Valve Stenosis, HDL
- Trial name
- NCT05641584
- Testing
- retrospective data review study
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Adenotonsillar Hypertrophy,Under 12 Years.
Intravenous Enhancin[Co-amoxiclav] Versus Postoperative Enhancin in Prevention of Postadenotonsillectomy Morbidity.
Null hypothesis; The efficacy of Enhancin]Co-Amoxiclav given as a single intravenous dose at induction is not better than a five days oral course of the same given postoperatively in reducing postoperative morbidity after…
- Trial name
- NCT01267942
- Testing
- Enhancin
- Where
- Kenya
- Volunteers
- 126 people
- Sponsor
- University of Nairobi
Patients Undergoing Valvular Heart Surgery
Impact of Preoperative Nutritional Status on the Postoperative Mortality and Morbidity in Patients Undergoing Valvular Heart Surgery
The investigators investigated the clinical impacts of preoperative nutritional status on mortality in patients undergoing valvular heart surgery.
- Trial name
- NCT04307732
- Where
- South Korea
- Volunteers
- 2,000 people
- Sponsor
- Yonsei University
Cesarean Section
The Timing of Prophylactic Antibiotics in Cesarean Section and the Risk of Post-operative Febrile Morbidity
The purpose of this study is to determine whether the timing of prophylactic antibiotic administration for cesarean section (immediate preoperative versus intraoperative administration) impacts the rate of postoperative febrile…
- Trial name
- NCT00133029
- Testing
- Timing of prophylactic antibiotic administration
- Where
- United States
- Sponsor
- University of Pennsylvania
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Febrile Morbidity, Pain
Post-Operative Treatment With Ketorolac After Abdominal Myomectomy
The purpose of this study is to determine if ketorolac, given after abdominal myomectomy, will decrease the frequency of post-oerative fevers as well as improve post-operative pain management.
- Trial name
- NCT00845754
- Testing
- ketorolac, saline
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ascher-Walsh, Charles, M.D.
Cesarean Section, Surgical Site Infection
Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor
Surgical site infections (SSI) are the second most common cause of nosocomial infections accounting for 15% of all nosocomial infections among hospitalized patients and 38% of nosocomial infections in surgical patients.
- Conditions
- Cesarean Section, Surgical Site Infection, Nosocomial Infection
- Trial name
- PRACTICAL (NCT03423147)
- Testing
- 2% chlorhexidine gluconate cloth, 4% Chlorhexidine gluconate vaginal scrub
- Where
- United States
- Volunteers
- 319 people
- Sponsor
- Angela Bianco
Non Small Cell Lung Cancer, Fasting
Effect of Preoperative Oral Carbohydrate Administration in Thoracic Surgery Patients
Preoperative carbohydrate loading has been shown to reduce pre-operative discomfort and postoperative nausea and vomiting. There is no need for prolonged preoperative fasting of the patients, but the traditional approach still…
- Conditions
- Non Small Cell Lung Cancer, Fasting, Postoperative Pneumonia
- Trial name
- oralcarbohydra (NCT05005091)
- Testing
- Oral carbohydrate
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital
Surgical Risk Assessment, Postoperative Mortality
Preoperative Cardiac Power Output and P-POSSUM Score
This study aims to investigate the relationship between preoperative Cardiac Power Output (CPO), which reflects the pumping capacity of the heart, and the P-POSSUM score, a widely used surgical risk assessment tool, in patients…
- Conditions
- Surgical Risk Assessment, Postoperative Mortality, Postoperative Morbidity
- Trial name
- NCT07454564
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Necmettin Erbakan University
Impacted Third Molar Tooth
The Effect of Saline Irrigation at Different Temperatures on Pain, Edema, and Trismus After Impacted Third Molar Surgery
Third molar surgery is one of the most common procedures in oral surgery and the most common postoperative complications are swelling, pain, and trismus.
- Trial name
- NCT05170516
- Testing
- 4 °C colled saline irrigation, 10 °C cooled saline irrigation, Room temperature saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Trakya University
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Hip Fractures
Pre- and Post-Operative Exercise in Patients With Hip Fracture
The purposes of this study are to determine the benefits of a pre-operative aerobic exercise program and an 8-week postoperative aerobic exercise program with a portable upper extremity cycle-ergometer in patients with hip…
- Trial name
- NCT05389800
- Testing
- Upper Extremity Aerobic Exercise
- Where
- Greece
- Volunteers
- 116 people
- Sponsor
- National and Kapodistrian University of Athens
Fracture, Infection
A Geriatric Home Visit Program to Reduce Post-Hip Fracture Complications
The overall goal of the project is to reduce the incidence of post hip fracture morbidity and mortality by conducting geriatric fellow periodic home visits.The assessment will be multidisciplinary and will include assessments of…
- Conditions
- Fracture, Infection, Depression, Gait Instability
- Trial name
- NCT02058329
- Testing
- Home Visit
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwell Health