Clinical trials: Postoperative Outcomes
Inguinal Hernia
Comparative Study on the Post-operative Pain and Other Outcomes of Mesh Fixation With Prolene vs Vicryl vs Skin Staples in Lichtenstein Inguinal Hernia Repair.
We are going to see the outcome measures for patient and compare them across two groups, those who are undergoing mesh fixation for inguinal hernia by sutures, and those who are fixated by skin staples.
- Trial name
- NCT07210424
- Testing
- Mesh Fixation
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Postoperative Nausea and Vomiting (PONV), Postoperative Pain
Effect of Timing of Dexamethasone During Induction on Postoperative Outcomes
This study aims to investigate how the timing of dexamethasone administration during anesthesia induction affects patient outcomes after surgery.
- Conditions
- Postoperative Nausea and Vomiting (PONV), Postoperative Pain, Inflammatory Response to Wounding, Hyperglycemia Drug Induced
- Trial name
- TIDE (NCT06685991)
- Testing
- Dexamethasone
- Volunteers
- 300 people
- Sponsor
- AABDI Mohammed
Aneurysm, Brain
Prediction of Outcomes After Surgery for Unruptured Intracranial Aneurysms
Accurate preoperative identification of patients at high risk for adverse outcomes would be clinically advantageous, as it would allow enhanced resource preparation, better surgical decision-making, enhanced patient education and…
- Trial name
- PRAEMIUM (NCT04819074)
- Testing
- Microsurgery
- Where
- 37 sites in United States, Australia and 8 more
- Volunteers
- 4,000 people
- Sponsor
- University of Zurich
Total Knee Arthroplasty
REST-Knee: A Pilot RCT of 72-Hour Knee Immobilization and Pain Outcomes
Postoperative pain following total knee arthroplasty (TKA) is often difficult to manage, particularly with the increasing use of outpatient surgery where patients recover at home.
- Trial name
- REST-Knee (NCT07511842)
- Testing
- Knee Extension Brace (Zimmer-type), Early Mobilization (Standard Care)
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Université de Sherbrooke
Patients Scheduled to Undergo Surgery on the Gynecology Service
Electronic Reporting of Symptoms After Surgery
The purpose of this pilot study is to find out if patients are willing to self-report symptoms in the first 5 days following discharge, or when they leave the hospital after "ambulatory surgery" ("ambulatory surgery" is when the…
- Trial name
- NCT02700256
- Testing
- survey
- Where
- 5 sites in United States
- Volunteers
- 135 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cervical Cancer Stage IB2, Cervical Cancer Stage IIa
Minimally Invasive Radical Hysterectomy Using Endoscopic Stapler in Stage IB2 or IIA1 Cervical Cancer
This study is a multicenter, open-label, non-inferiority, randomized controlled, investigator-initiated clinical trial comparing the efficacy and safety of open radical hysterectomy versus minimally invasive radical hysterectomy…
- Trial name
- SOLUTION2 (NCT07256977)
- Testing
- Open radical hysterectomy, Minimally invasive radical hysterectomy
- Where
- South Korea
- Volunteers
- 494 people
- Sponsor
- Seoul National University Hospital
Endometriosis, Deep Endometriosis
Retrospective Analysis of Results of Surgery for Deep Bowel Endometriosis
identification of patients operated becaus of bowel endometriosis at the endometriosis center, University Hospital Muenster, Germany, starting 2009, Analysis of Patient history, surgical procedurie, intraoperative complications…
- Conditions
- Endometriosis, Deep Endometriosis, Bowel Endometriosis, Reproductive Issues
- Trial name
- NCT04669769
- Testing
- interview
- Where
- Germany
- Volunteers
- 151 people
- Sponsor
- University Hospital Muenster
Distal Pancreatectomy
Pancreatic Stent for Distal Pancreatectomy
The purpose of this study is to compare outcomes of patients undergoing distal pancreatectomy with or without pancreatic stent
- Trial name
- NCT03314337
- Testing
- Pancreatic stent: PSOF COOK®
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Ruijin Hospital
Colon Neoplasms, Rectal Neoplasms
The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery
In colorectal surgery, anastomotic leak and its septic consequences still remain as the most concerning complications resulting in substantial morbidity and mortality.
- Conditions
- Colon Neoplasms, Rectal Neoplasms, Inflammatory Bowel Disease, Diverticular Disease
- Trial name
- NCT02598414
- Testing
- Near-infrared ICG fluorescence imaging, Traditional bowel anastomosis, FireFly™
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Acibadem University
Impact Molar
Clinical and Radiographic Evaluation of Local Application of Melatonin on Postoperative Outcomes After Surgical Removal of Impacted Mandibular Third Molar
Clinical and Radiographic Evaluation of Local Application of Melatonin on Postoperative Outcomes after Surgical Removal of Impacted Mandibular Third Molar: A Randomized Controlled Study
- Trial name
- NCT07374536
- Testing
- Control, Melatonin gel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Breast Cancer, Mastectomy
Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer
The goal of this clinical trial is to learn if the AMADeuS care pathway is as safe as usual hospital care and works as well for pain control in women having mastectomy with immediate prepectoral breast reconstruction.
- Conditions
- Breast Cancer, Mastectomy, Prepectoral Breast Reconstruction, ERAS Programmes
- Trial name
- AMADeuS (NCT07510698)
- Testing
- AMADeuS Perioperative Pathway, Usual Perioperative Care
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Gastric Cancer (GC)
Prehabilitation Plus ERAS in Gastric Cancer Surgery
This study aims to evaluate the impact of pre-habilitation combined with Enhanced Recovery After Surgery (ERAS) versus ERAS perioperative management alone on clinical outcomes in patients with gastric cancer undergoing…
- Trial name
- NCT07328633
- Testing
- Pre-habilitation Program, Enhanced Recovery After Surgery (ERAS) Protocol
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Obesity, Bariatric Surgery Candidate
RemI for Post-Bariatric Surgery Weight Regain
The goal of this clinical trial is to test the effectiveness of remotely-delivered interventions (utilizing acceptance-based behavioral treatment skills (ABTi)) amongst bariatric surgery populations who are experiencing weight…
- Trial name
- NCT06292936
- Testing
- Acceptance-Based Behavioral Intervention
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Temple University
Pulmonary Hypertension (Diagnosis), Pre-operative Assessment
GUARD-PH: Guided Use of AI-ECG for Risk Detection of PH in Surgery (GUARD-PH Trial)
This study is a prospective, open-label, randomized controlled trial designed to evaluate a new artificial intelligence (AI) tool for heart monitoring.
- Conditions
- Pulmonary Hypertension (Diagnosis), Pre-operative Assessment, Postoperative Complications (Cardiopulmonary), Treatment Outcomes
- Trial name
- GUARD-PH (NCT07344207)
- Testing
- Artificial Intelligence-Enabled Electrocardiography System
- Where
- Taiwan
- Volunteers
- 1,380 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Patient Satisfaction, Sports Injury
Virtual Phone Visits Compared to In-Person Physical Visits for Post-Operative Follow-Up at a Sports Medicine Clinic
This study will compare patient reported outcomes (PROs) of patients seen at virtual phone visits compared to in-person visits for 6 weeks, 12 weeks, and 6 months post-operative follow up at a sports medicine clinic.
- Conditions
- Patient Satisfaction, Sports Injury, Surgery, Orthopedic Disorder
- Trial name
- NCT05998148
- Testing
- virtual phone appointment visits
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Jonathan Wu
Root Canal Infection
Toluidine Blue-Based Photodynamic Therapy for Antibacterial Activity and Postoperative Pain
This clinical study aims to evaluate the antimicrobial effectiveness and postoperative pain outcomes of photodynamic therapy using Toluidine Blue O as an adjunct to conventional root canal treatment in patients diagnosed with…
- Trial name
- NCT07266233
- Testing
- Toluidine Blue O (0.1 mg/mL), 630-nm LED Light Device, Photodynamic Therapy (PDT)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ataturk University
Post-operative Complications
Improving Surgical Patient Outcomes Through Implementation of a SemiStructured Intraoperative Anesthesia Handoff Tool
The purpose of this study is to assess the impact of a semi-structured intraoperative anesthesia handoff tool on patient outcomes and to assess the validity of the 5-Factor Perceived Shared Mental Model Scale (5-PSMMS) in a…
- Trial name
- NCT06533111
- Testing
- Epic Health Record semi-structured handoff cognitive aid, Usual care
- Where
- United States
- Volunteers
- 3,763 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chest Wall Tumor, Reconstructive Surgical Procedure
Chest Wall Reconstruction Cohort
Chest wall reconstruction following tumor or infection-related resections remains a challenging aspect of thoracic surgery, requiring restoration of structural stability and preservation of respiratory mechanics.
- Conditions
- Chest Wall Tumor, Reconstructive Surgical Procedure, Malignancy
- Trial name
- NCT07338006
- Testing
- chest wall reconstruction
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Health Sciences Lahore
Abdominal Surgery Complications, Hypothermia Following Anesthesia
The Effect of Heating the Intensive Care Room in the Early Postoperative Period on Patient Outcomes
The aim of this study was to evaluate the effect of heating the intensive care room in the early postoperative period on patient outcomes.
- Trial name
- NCT07137143
- Testing
- The rooms of the intervention group patients will be heated before they come to intensive care and the temperature of the room will be increased.
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Cukurova University
Hand, Hand Therapy
Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System
This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later.
- Conditions
- Hand, Hand Therapy, Upper Extremity, Prediction Models
- Trial name
- HANDREHPREDICT (NCT07522060)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University