Clinical trials: Postoperative Pain, Acute
Pain, Acute Pain
Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.
Pain is a symptom that drives hospital admissions, and pain management is required by most patients during their hospital stay. Further, the use of medications such as opioids can lead to upward-spiraling doses, especially among…
- Conditions
- Pain, Acute Pain, Postoperative Pain
- Trial name
- NCT02470728
- Testing
- New Clinical Pathway
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Pain, Acute
The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines
To understand the impact of perioperative hydrogen inhalation on post-operative pain control and serum inflammation markers
- Trial name
- NCT05476575
- Testing
- hydrogen inhalation, 4% concentration, given via nasal cannula
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Fu Jen Catholic University Hospital
Post Operative Pain, Acute
Comparison Between the Analgesic Effect of Fascia Transversalis Block vs Caudal Block
Despite the growing interest in interfascial blocks and their successful use in pediatric surgeries, no previous randomized clinical trials have directly compared the analgesic efficacy, opioid-sparing effect, and safety profile…
- Trial name
- NCT07235475
- Testing
- Caudal Block Anesthesia, Fascia Transversalis Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pain
Nicotine Patch as an Analgesic Adjuvant After Surgery
Effect of nicotine patch as an adjutant for acute pain after surgery.
- Trial name
- NCT00440830
- Testing
- nicotine patch
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Columbia University
Nausea, Vomiting
Predictive Factors for Postoperative Pain, Nausea and Vomiting in Oncological Patients
1809 patients were evaluated in postoperative period. They were asked about nausea, vomiting, retching and pain in the first postoperative 24 hours
- Conditions
- Nausea, Vomiting, Pain, Postoperative
- Trial name
- PONV (NCT04889534)
- Testing
- Analgesia
- Where
- Brazil
- Volunteers
- 1,500 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Pain, Postoperative
Scheduled or as Needed Pain Regimen?
The aim of this study is to determine feasibility of a randomized controlled trial and estimates of efficacy for pain control of a scheduled pain regimen versus an as needed pain regimen for participants undergoing same day…
- Trial name
- NCT06495632
- Testing
- Motrin and narcotic
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cape Fear Valley Health System
Postoperative Pain, Spinal Fusion
Sufentanil NanoTab PCA System/15 mcg for Acute Post-Operative Pain in Vertebral Surgery: A Preliminary Investigation
The Zalviso® Sufentanil Sublingual Tablet System (SSTS) (Grünenthal Italia, Milan, Italy) is a patient-controlled analgesia (PCA) system approved in September 2015 by the European Commission for the management of acute…
- Conditions
- Postoperative Pain, Spinal Fusion, Spondylolisthesis, Lumbar Region, Sufentanil
- Trial name
- NCT03459404
- Testing
- Sufentanil NanoTab PCA System
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postoperative Pain, Hemorrhoids Third Degree
Efficacy of Ice Packing Application in Post-Hemorrhoidectomy Recovery
According to the previous study, surgical intervention exhibited significant differences in daily life before and after a hemorrhoidectomy.
- Conditions
- Postoperative Pain, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids
- Trial name
- ICE-HEMO (NCT07186348)
- Testing
- Ice packing, Standard Care (in control arm)
- Where
- Taiwan
- Volunteers
- 429 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer, Postoperative Pain
Prediction of Pain After Breast Cancer Surgery With EEG
1. Rationale The inter-individual pain experience immediately after surgery is considerable. In addition, a number of patients develop chronic post surgery pain (CPSP).
- Conditions
- Breast Cancer, Postoperative Pain, Chronic Pain
- Trial name
- NCT01392248
- Where
- Netherlands
- Volunteers
- 4 people
- Sponsor
- Maastricht University Medical Center
Postoperative Pain, Analgesia
Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy
Supratentorial craniotomy is one of the most common neurosurgical procedures, with severe perioperative pain. Inadequate perioperative pain relief has been associated with increased blood pressure and intracranial pressure…
- Conditions
- Postoperative Pain, Analgesia, Supratentorial Brain Tumor
- Trial name
- NCT06406829
- Testing
- Dexmedetomidine, Normal saline, Local analgesic techniques
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Pain, Acute, Postoperative Pain, Chronic
Application of Non-invasive Neurophysiological Methods in Predicting and Evaluating Postoperative Pain in Adult Patients Undergoing Major Thoracic Surgery
The primary aim of this study is to explore the relationship between alpha electroencephalographic oscillations, particularly Peak Alpha Frequency (PAF), pupillometry, intraoperative Nociception Level (NOL) and postoperative pain…
- Conditions
- Postoperative Pain, Acute, Postoperative Pain, Chronic, Postoperative Pain After Thoracic Surgery
- Trial name
- NCT06731010
- Where
- 2 sites in Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Postoperative Pain, Acute, Anaesthetic
Analgesic Effect of Intraoperative Intravenous S-Ketamine During Total Knee Arthroplasty Surgery
Severe acute pain after total knee arthroplasty surgery has multiple implications for hospitals and patients, monopolising resources and affecting the quality of life.
- Trial name
- NCT05289050
- Testing
- sodium chloride (NaCl; 0.9%), S-ketamine
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Ling Dong
Breast Cancer, Acute Postoperative Pain
Combined PECS II and Transversus Plane Blocks Versus Erector Spinae Block in Modified Radical Mastectomy
The aim of this study is to compare the total morphine consumption in the first 24 hour postoperative between combined modified pectoralis block (PECS II) and transversus plane block versus erector spinae block in modified…
- Trial name
- NCT03903224
- Testing
- Combined Modified Pectoralis and Transversus Plane Blocks, Erector Spinae block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post Operative Pain, Acute
Effect of Two Different Concentrations of Sodium Hypochlorite on Post-Operative Pain Following Single-Visit Root Canal Treatment
This randomized controlled trial aims to evaluate the effect of two different concentrations of sodium hypochlorite (2.5% and 5.25%) on post-operative pain following single-visit root canal treatment.
- Trial name
- NaOCl-RCT (NCT07618182)
- Testing
- Sodium Hypochlorite Irrigation
- Volunteers
- 116 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Total Abdominal Hysterectomy ,Pain , Acute Postoperative,Gabapentin , Celecoxib
Preoperative Analgesia in Non-gynecological Cancerous Women Who Underwent Elective Total Abdominal Hysterectomy
Comparison of effectiveness of preoperative Gabapentin with Celecoxib in reducing acute postoperative pain in abdominal hysterectomy, A randomized double blind controlled trial
- Trial name
- NCT03672162
- Testing
- Total abdominal hysterectomy
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Cardiovascular Surgical Procedures, Pain, Postoperative
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB…
- Conditions
- Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases
- Trial name
- NCT07557108
- Testing
- Ultrasound-Guided Pectointercostal Fascial Plane Block, Ultrasound-Guided Rectus Sheath Block, Ultrasound-Guided Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Ordu University
Necrotic Pulp, Acute Apical Periodontitis of Pulpal Origin
Clinical Efficacy of Novel Jasminum-based Calcium Hydroxide Medicament
A triple-blind, parallel group, randomized trial with an allocation ratio of 1:1. Participants randomly allocated into two groups A and B.
- Trial name
- NCT06653608
- Testing
- Nano-reinforced calcium hydroxide medicament, Calcium hydroxide without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Other Acute Postoperative Pain
Study of Indomethacin Capsules to Treat Pain Following Bunionectomy
The purpose of this study is to determine whether Indomethacin [Test] Capsules are safe and effective for the treatment of postoperative bunionectomy pain.
- Trial name
- NCT01626118
- Testing
- Indomethacin
- Where
- 4 sites in United States
- Volunteers
- 373 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Labor Pain, Pain, Postoperative
Spinal Analgesia as Fast Track Painless Labor
The purpose of this prospective, randomized, and controlled trial was to compare the efficacy of single-shot spinal analgesia to typical conventional treatments (continuous epidural analgesia and spinal-epidural combination) in…
- Conditions
- Labor Pain, Pain, Postoperative, Pain, Acute
- Trial name
- NCT05271760
- Testing
- Single-shot spinal analgesia, Continuous epidural analgesia, Combined spinal-epidural analgesia
- Where
- Saudi Arabia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University