Clinical trials: Postoperative Pain, completed
Breast Carcinoma, Breast Carcinoma in Situ
Postoperative Pain After Breast Surgery Under Tumescent Local Anaesthesia Versus General Anaesthesia ( TLA-001 )
The present study aims to investigate the impact of Tumescent Local Anesthesia (TLA) on pain perception following surgeries typical for breast cancer.
- Trial name
- NCT06335108
- Testing
- General Anaesthesia, Local tumescent anaesthesia
- Where
- Germany
- Volunteers
- 349 people
- Sponsor
- University Hospital Tuebingen
Postoperative Pain Atskin Graft Site
Comparison of Bupivacaine Versus Bupivacaine-dexamethasone Infiltration for Postoperative Analgesia in Skin Graft Donor Sites
Background: Skin grafting; both partial and complete thickness is frequently used in reconstruction of traumatic soft tissue defects.
- Trial name
- NCT03967392
- Testing
- Xylocaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Malignant Neoplasm of Breast
MIRs03: Paravertebral Block With Ropivacaine Before Breast Cancer Surgery
Compare the effect of paravertebral block (PVB) with Ropivacaine or placebo on the incidence of chronic pain 3 months after breast cancer surgery.
- Trial name
- MIRs03 (NCT02408393)
- Testing
- Saline, Ropivacaine
- Where
- 6 sites in France
- Volunteers
- 380 people
- Sponsor
- Institut Curie
Pain, Postoperative
Caudal Block With Tramadol and Levobupivacaine or Bupivacaine
Caudal block is the regional anesthetic technique that is used most frequently in pediatric surgery. Opioid drugs have been added to local anesthetic solutions to prolong duration of analgesia but ideal combination were not found…
- Trial name
- NCT01974843
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Duzce University
Femoral Neck Fracture
Postoperative Analgesia With Local Infiltration After Femoral Neck Fracture
Reducing pain is an essential factor for early mobilization after osteosynthesis of femoral neck fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT00529425
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Postoperative Pain
Evaluation of Smartphone Versions of VAS and NRS for Use in Adults
A large number of patients experience significant pain after surgery, and more patients report pain after discharge from hospital than before.
- Trial name
- Panda (NCT04139590)
- Testing
- Panda, Visual Analogue Scale - Original
- Where
- 2 sites in Canada
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Post Operative Pain
Clavipectoral Block Versus Interscalene Block for Postoperative Analgesia in Midshaft Clavicular Surgery
The aim of this study is to compare between (ISBPB) and (CPB) as postoperative analgesic technique following midshaft clavicular fracture open reduction and internal fixation surgeries.
- Trial name
- NCT06917820
- Testing
- Interscalene brachial plexus block, Clavipectoral fascia plane block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Liver Cancer, Hepatectomy
Effects of Different Anesthetic Techniques on Intraoperative and Postoperative Pain Levels and Cognitive Function in Patients Undergoing Hepatectomy for Liver Cancer
To evaluate the effects of general anesthesia (GA) versus combined general and epidural anesthesia (GEA) on postoperative pain, cognitive dysfunction (POCD), hospital stay, and recovery quality in liver cancer patients undergoing…
- Conditions
- Liver Cancer, Hepatectomy, Anesthesia Techniques, Postoperative Pain
- Trial name
- NCT07097220
- Testing
- General Anesthesia (GA) group, General-Epidural Anesthesia (GEA) group
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Sir Run Run Shaw Hospital, Qingchun Campus, Zhejiang University School of Medicine,
Adult Patients Scheduled for 3rd Molar Teeth Extractions
Comparison of Two Different Doses of Paracetamol for Post-Operative Pain Relief
Paracetamol is commonly used to reduce pain after operations. Recently anaesthetists have been using bigger doses of paracetamol because it has been suggested that bigger doses will work better.
- Trial name
- NCT00286650
- Testing
- 3rd molar teeth extraction
- Where
- New Zealand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Otago
Post Operative Pain, Chronic Apical Periodontitis of Pulpal Origin
The Effect of Using Reciprocal Files Alone and With Different Files on Postoperative Pain
This study aims to investigate the effects of using the Wave One Gold file alone and in combination with different files on postoperative pain in patients with asymptomatic apical periodontitis.
- Trial name
- NCT06833515
- Testing
- one flare+wave one gold glider+wave one gold, wave one gold glider+wave one gold, wave one gold
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Harran University
Postoperative Pain
Ice Application for Postoperative Pain
The purpose of the proposed study is to investigate the effectiveness of cryotherapy as an additional form of pain control in women undergoing laparoscopic hysterectomy for benign gynecologic conditions through a randomized trial.
- Trial name
- Ice-POP (NCT04145791)
- Testing
- Ice
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Post-operative Pain, Thoracic Epidural
Dexmedetomidine and Fentanyl as Adjuvants to Thoracic Epidural
To find out if there is a benefit from adding dexmedetomidine to epidural bupivacaine as regards: Intra and postoperative opioid consumption Pain score (numerical rating scale) Hemodynamic stability, Patient satisfaction.
- Conditions
- Post-operative Pain, Thoracic Epidural, Thoracotomy Surgery
- Trial name
- adjuvants (NCT06489574)
- Testing
- thoracic epidural with dexmedetomidine in patients undergoing thoracotomy surgery, thoracic epidural with fentanyl in patients undergoing thoracotomy surgery
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgery, Pain
A Dose Ranging Effect of Preoperative Diphenhydramine on Postoperative Quality of Recovery After Ambulatory Surgery
Pain after ambulatory surgery remains an unsolved problem in The United States and Europe. It is associated with delayed hospital discharge and it can result to an increased opioid consumption with adverse side effects.
- Trial name
- NCT01451762
- Testing
- .9 normal saline, 25 mg diphenhydramine IV, 50 mg diphenhydramine IV
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University
Failed Back Surgery Syndrome
Subcutaneous Peripheral Nerve Stimulation (PNS) as "Hybrid Stimulation" After Failure of Spinal Cord Stimulation (SCS) to Control the Back Pain Component in Failed Back Surgery Syndrome (FBSS) Patients.(CUMPNS Study)
Despite globally favourable outcomes of Spinal Cord Stimulation (SCS), a significant proportion of Failed Back Surgery Syndrome (FBSS) patients do not obtain adequate coverage of low back pain.
- Trial name
- NCT02110888
- Testing
- Subcutaneous peripheral nerve stimulation, SCS Only
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Poitiers University Hospital
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Inguinal Hernia
Mesh Fixation Methods in Laparoscopic Hernia Repair: Glue vs. Sutures vs. Tacks
This study is a clinical trial that aims to compare three different methods for securing a surgical mesh during a specific type of groin (inguinal) hernia repair surgery.
- Trial name
- RCT (NCT07401082)
- Testing
- Cyanoacrylate Surgical Adhesive Fixation, Suture Mesh Fixation, Helical Titanium Tack Fixation
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Pain, Postoperative
Transversus Abdominis Plane Block in Iliac Crest harvest-is it Beneficial?
The purpose of this study is to determine whether a supplemental Transversus Abdominis Plane block administered intraoperatively improves the postoperative parameters in patients undergoing Alveolar bone grafting with iliac crest…
- Trial name
- NCT02997124
- Testing
- local infiltration and TAP block, local infiltration only
- Volunteers
- 143 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Pain
A Study to Evaluate the Efficacy and Safety of HRS4800 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.
The study is being conducted to evaluate the efficacy and safety of HRS4800 tablets for postoperative analgesia after impacted teeth removal surgery.
- Trial name
- NCT05318846
- Testing
- HRS4800 tablets
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Pain, Postoperative
Efficacy of Dexmedetomidine as an Adjuvant to Quadratus Lumborum Block
This prospective double blinded study will be conducted over 60 pediatric patients ASA (American Association of Anesthesiologists) I and II between the age of 1-7 years old, who will be scheduled for unilateral groin surgery.
- Trial name
- NCT05979376
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Breast Cancer Surgery
Effect of Intravenous S-ketamine on Opioid Consumption
Female patients with an American Society of Anesthesia (ASA) physical status I-II, scheduled for elective breast cancer surgery will be included in the study.
- Trial name
- NCT05060068
- Testing
- S-ketamine (low dose), S-ketamine (high dose)
- Where
- China
- Volunteers
- 345 people
- Sponsor
- The Second Hospital of Anhui Medical University
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