Clinical trials: Postoperative Pain After Cesarean Section
Postoperative Pain, Post-Cesarean Section
Comparing Protocols for Analgesia Following Elective Cesarean Section
Women undergoing elective cesarian section will be assigned to 3 groups for postoperative analgesia: 1. Scheduled doses of IV acetaminophen + PO Ibuprofen 2. Scheduled doses of PO acetaminophen + PO Ibuprofen 3.
- Trial name
- NCT03622489
- Testing
- Acetaminophen, Ibuprofen 400 mg, Dipyrone
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Pain, Postoperative
Comparison Levobupivacaine and Ropivacaine for TAP-block After Caesarean Section
Randomized, double-blind, controlled trial: a comparison of Levobupivacaine and Ropivacaine for postoperative analgesia using TAP-block Objectives: 1. VAS score during the first 12 hours 2.
- Trial name
- NCT03302689
- Testing
- Levobupivacaine Solution, Ropivacaine Solution
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandr Ronenson
Cesarean Section Complications
Knot Burial Technique for Rectus Sheath Closure
Caesarean section is one of the most commonly performed abdominal operations on women in most countries of the world. Its rate has increased markedly in recent years, and is about 20-25% of all child-births in most developed…
- Trial name
- NCT04156282
- Testing
- knot burial technique, classical closure
- Where
- Egypt
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain, Cesarean Section Pain
Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section
This study aims to compare three different doses of dexmedetomidine, when combined with a fixed dose of ketamine, for pain control in women undergoing cesarean section.
- Trial name
- KETODEX-CS (NCT07022821)
- Testing
- Dexmedetomidine, ketamine
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Memorial Hospital
Post Operative Pain
Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management
This is a randomized controlled trial involving 170 opioid naive women ages 19-40 undergoing scheduled C-sections at Carilion Roanoke Memorial Hospital.
- Trial name
- NCT05360433
- Testing
- Oxycodone oral capsule
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Cesarean Section Complications
Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia
This randomized, double-blind, controlled clinical trial will compare the effectiveness of a single intravenous dose of magnesium sulphate versus dexamethasone as an adjuvant to ultrasound-guided transversus abdominis plane (TAP)…
- Trial name
- NCT07773220
- Testing
- Magnesium Sulphate 500 mg, Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Transversus Abdominis Plane (TAP) Block, Wound Infiltration
Ultrasound-guided Transversus Abdominis Plane Block Versus Local Wound Infiltration (TAP_WI)
The goal of this clinical trial is to learn if transversus abdominis plane (TAP) block will reduce the cumulative opioid consumption compared to local wound infiltration (WI).
- Conditions
- Transversus Abdominis Plane (TAP) Block, Wound Infiltration, Pain Score (VAS), Opioid Analgesia
- Trial name
- TAP (NCT06627946)
- Testing
- TAP group
- Where
- Bhutan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Cesarean Delivery, Postpartum Comfort
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks.
- Conditions
- Cesarean Delivery, Postpartum Comfort, Postpartum Pain, Post-operative Pain
- Trial name
- PACESS (NCT07102641)
- Testing
- Acetaminophen, NSAID (Ketorolac/Ibuprofen)
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Thomas Jefferson University
Over 18 Years Old
Innovative Methods in Postoperative Pain Management: A Study on the Effects of Kinesio Taping After Cesarean Section
Brief Summary: This randomized, single-blind study aimed to evaluate the effects of kinesio taping on pain management, comfort, and satisfaction of women after cesarean section.
- Trial name
- NCT06661109
- Testing
- Intervention (Kinesio Taping) group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mersin University
Postoperative Pain, Recovery After Cesarean Delivery
Kinesio Taping for Pain and Recovery After Cesarean Delivery
This study examined whether elastic therapeutic tape, known as kinesio tape, applied to the lower abdomen after cesarean delivery could reduce pain and improve recovery when added to standard postoperative care.
- Trial name
- NCT07855809
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ibrahim Ethem Kirez
Postoperative Pain, Patiet Controlled Analgesia
Comparison of the Effects of Hydromorphone and Nalbuphine Patient Controlled Analgesia in Postoperative Pain After Cesarean Section
Cesarean section is an essential surgical procedure in obstetrics, which not only addresses dystocia and certain obstetric syndromes, ensuring the safety of the maternal participants, but also increases perinatal survival rates…
- Trial name
- NCT06716359
- Testing
- Observational study without intervention
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Huazhong University of Science and Technology
Post Surgical Pain
Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section
The study aims to improve the care of the obstetric population after cesarean section and improve total patient satisfaction by improving post-surgical pain control with the use of dexamethasone in combination with bilateral TAP…
- Trial name
- NCT03098420
- Testing
- 2mg Dexamethasone, 4mg Dexamethasone, Ropivacaine (TAP blocks)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cesarean Section, Pain, Acute
Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)
The investigators are comparing post operative analgesia provided for caesarean section patients, with the quadratus lumborum type 2 block and intrathecal morphine.
- Trial name
- NCT03267628
- Testing
- Intrathecal morphine as well as local anaesthetic in Blocks, Intrathecal morphine as well as saline in Block, Saline intrathecal as well as saline in Blocks
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr Willem Basson
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Postoperative Pain
Transversus Abdominis Plane Block Versus Rectus Sheath Block After Cesarean Delivery
Importance of effective postoperative pain management is well known. The undesired effects of pain can be prevented with multimodal analgesia for the patient.
- Trial name
- NCT03811067
- Testing
- Transversus abdominis plane block, Rectus sheath block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kocaeli University
Cesarean Section, Pain, Postoperative
Use of Virtual Reality Glasses for Pain and Anxiety After Cesarean
The goal of this randomized controlled trial is to examine the effect of preoperative virtual reality used before cesarean on postoperative pain and anxiety.
- Conditions
- Cesarean Section, Pain, Postoperative, Anxiety
- Trial name
- NCT06232057
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Amasya University
Pain
Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
The purpose of this study is to determine if the infusion of the local anesthetic ropivacaine (a numbing medicine) and the non-steroidal anti-inflammatory drug ketorolac (a pain killer similar to ibuprofen) through a catheter…
- Trial name
- NCT02829944
- Testing
- Ropivacaine, Ketorolac
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Duke University
Postoperative Pain
Ultrasound-guided Quadratus Lumborum Block for Postoperative Pain Relief After Cesarean Delivery
The Quadratus Lumborum (QL) Block is an ultrasound-guided technique described by Rafael Blanco in 2007. The nerves to the lower abdominal wall can be anesthetized by injecting local anesthetics close to the anterior border of the…
- Trial name
- NCT02036749
- Testing
- nerve block
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Pain, Postoperative, Depression, Postpartum
Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)
The purpose of this study is to identify a tolerable dose for postpartum ketamine infusion using a maximum tolerated dose (MTD) 3+3 design.
- Trial name
- NCT05907213
- Testing
- Ketamine (Ketalar) Dose Level 1, Ketamine (Ketalar) Dose Level 2, Ketamine (Ketalar) Dose Level 3
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS