Clinical trials: Postoperative Pain Relief
Postoperative Pain, Analgesia
PENG Block Combined to Wound Infiltration for Hip Replacement
This study analyze the effect of Pericapsular Nerve Group (PENG) Block combined to wound infiltration for analgesia after elective hip replacement.
- Conditions
- Postoperative Pain, Analgesia, Hip Arthropathy, Acute Pain
- Trial name
- NCT04306133
- Testing
- PENG block, Wound Infiltration
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Preoperative, Ultrasound-Guided
Preoperative Ultrasound-Guided Peri- Capsular Nerve Group Block on Postoperative Analgesia After Shoulder Arthroscopic Surgery
This study aimed to evaluate the analgesic efficacy of preoperative ultrasound-guided peri-capsular nerve group block (PENG) on postoperative analgesia after shoulder arthroscopic surgery.
- Conditions
- Preoperative, Ultrasound-Guided, PeriCapsular Nerve Group Block, Postoperative Analgesia
- Trial name
- NCT06790732
- Testing
- Saline, Bupivacaine + Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Laparoscopic Cholecystectomy
Retrolaminar Block Versus Intraperitoneal Block for Laparoscopic Cholecystectomy
Although laparoscopic cholecystectomy is a minimally invasive surgery, it causes moderate-severe pain. The aim of this study is to assess the quality of pain relief in patients who will undergo in laparoscopic cholecystectomy…
- Trial name
- NCT05755815
- Testing
- retrolaminar block, Peritoneal block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Efficacy of Bi-level ESPB Application in Patients Undergoing VATS
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Thoracic Surgery, Video-Assisted, Erector Spinae Plane Block, Multimodal Analgesia
- Trial name
- NCT05427955
- Testing
- One-level Erector Spinae Plane Block, Bi-level Erector Spinae Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain
The Analgesic Efficacy of Wound Infiltration With Tramadol
This double-blind, randomized trial examined whether tramadol wound infiltration decreased postoperative pain following cesarean delivery under general anesthesia or reduced the need for analgesics in the immediate postoperative…
- Trial name
- NCT02518438
- Testing
- Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University Hospital
Post-operative Pain, Anesthesia, Local
Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery
Total knee replacement surgery can be associated with a significant postoperative pain burden and an inability to mobilize adequately, which can lead to the failure of the ambulatory course.
- Trial name
- NCT06038851
- Testing
- Para-Sartorial Compartments (PACS) Block, Femoral Triangle Block (FTB), Infiltration between popliteal artery and capsule of the knee (IPACK) block
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Hemorrhoidectomy, Postoperative Analgesia
The Impact of Methylene Blue on the Quality of Recovery in Patients Undergoing Hemorrhoidectomy
Classical hemorrhoidectomy is known to be linked with significant postoperative pain, which can result in patient discomfort, extended hospital stays, and increased costs.
- Trial name
- NCT06747195
- Where
- 3 sites in China
- Volunteers
- 290 people
- Sponsor
- Qilu Hospital of Shandong University
Quadratus Lumborum Block
Comparison of Two Approaches of Quadratus Lumborum Block for Post-operative Analgesia in Radical Cystectomy
To compare the postoperative analgesic effect of two ultrasound guided approaches of quadratus lumborum block (QLB) (anterior and intramuscular) for radical cystectomy.
- Trial name
- NCT05089994
- Testing
- US guided injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Transurethral Resection of Prostate
Effectiveness of Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in TURP Surgery
The goal of this clinical trial is to compare pain after surgery in patients undergoing Transurethral Resection of Prostate. The main question it aims to answer are: Intrathecal nalbuphine as an adjuvant to local anesthetic will…
- Trial name
- NCT06153602
- Testing
- Nalbuphine Hydrochloride 10 MG/ML, Sodium Chloride 0.9 % in 5 ML Injection, Bupivacaine Hydrochloride, Spinal
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Chulalongkorn University
Quadratus Lumborum Block, Thoracic Paravertebral Block
A Trial Comparing Quadratus Lumborum Block (QLB) and Paravertebral Block (PVTB) for Postoperative Analgesia in Hepatectomy
Pain after hepatectomy can interfere with the patients' recovery and may contribute to developing long term pain. Opioids, e.g. morphine, fentanyl, sufentanil, works well for postoperative analgesia, but have several side effects…
- Conditions
- Quadratus Lumborum Block, Thoracic Paravertebral Block, Postoperative Analgesia, Hepatectomy
- Trial name
- NCT03540537
- Testing
- Patient-controlled intravenous analgesia, Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Pain, Acute
Evaluation of Pericapsular Nerve Group Block on Positioning Pain for Spinal Anesthesia in Hip Fracture Patients
The purpose of this study is to evaluate of analgesic effects of pericapsullar nerve group block which is performed preoperatively to assist positioning patients for performance of spinal anesthesia.
- Trial name
- NCT04871061
- Testing
- PENG Block, Conventional opioid analgesia (Fentanyl)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cigli Regional Training Hospital
Postoperative Pain
The Ketamine for Acute Postoperative Analgesia (KAPA) Trial
Postoperative pain remains an important challenge for both patients and clinicians. Despite advances in pain management techniques, many patients continue to describe their pain as moderate to severe immediately after surgery.
- Trial name
- KAPA (NCT04646694)
- Testing
- Ketamine
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Arthroplasty
The Effect of the Combined Use of Naloxone and Tramacet on Postoperative Analgesia in the Elderly
Ten patients 70 years and older having elective total hip/knee replacement surgery will be recruited to receive a continuous IV infusion of naloxone and oral tramacet for analgesia.
- Trial name
- NCT00665262
- Testing
- tramacet
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
İnguinal Hernia, Post Operative Pain
Comparison of QLB and TFP Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the effects of ultrasound-guided lateral Quadratus Lumborum Block (QLB) and Transversalis Fascia Plane (TFP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- NCT07604259
- Testing
- Lateral Quadratus Lumborum Block, Transversalis Fascia Plane Block, Port Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Pain, Postoperative, Inguinal Hernia Unilateral
Intrathecal Morphine and Transversalis Fascia Plane Block for Analgesia After Open Inguinal Hernia Repair
Inguinal hernia is a common surgical condition, and open inguinal hernia repair may be associated with significant postoperative pain.
- Conditions
- Pain, Postoperative, Inguinal Hernia Unilateral, Intrathecal Morphine, Transversalis Fascia Plane Block
- Trial name
- NCT07826741
- Testing
- Intrathecal Morphine Group, Transversalis Fascia Plane Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Post-operative Pain
To Evaluate the Effect of Wound Infiltration With Bupivacaine for Post-operative Pain Relief After Laparoscopic Cholecystectomy
To evaluate the effect of wound infiltration with 0.25% Bupivacaine in laparoscopic cholecystectomy in terms of pain severity, patient satisfaction level, quality of life, hospital stay and return to job and normal activities.
- Trial name
- NCT03958513
- Testing
- Bupivacaine, 0.9% normal saline
- Where
- Bangladesh
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Idiopathic Scoliosis
Analysis of Different Postoperative Analgesia Strategies Following Scoliosis Surgery
Idiopathic scoliosis surgery is a major surgery, causing significant post-operative pain which can have a significant impact, both for the patient and for society.
- Trial name
- SAPOS (NCT06194279)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Mastectomy, Modified Radical
Intraoperative Pectoral Block vs IV Analgesia for Pain After Modified Radical Mastectomy
There is difference in post operative pain between patients receiving inter- pectoral block and those receiving standard Intravenous analgesia(INJ TORADOL) in patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT07257874
- Testing
- bupivacaine 0.5% injection, Ketorolac 30 mg IV
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Superior Trunk Block Versus Interscalene Block for Post-operative Analgesia in Shoulder Surgeries
Efficacy and Safety of Superior Trunk Block Versus Interscalene Block for Post-operative Analgesia in Shoulder Surgeries
Efficacy and safety of superior trunk block versus interscalene block for post-operative analgesia in shoulder surgeries
- Trial name
- NCT05978427
- Testing
- interscalene block, superior trunk block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain
Effect of Intraperitoneal Nebulisation of Magnesium Sulphate for Analgesia Following Laparoscopic Cholecystectomy
intraperitoneal nebulisation with magnesuim sulphate will reduce post operative pain and analgesic consumption in postoperative period following laparoscopic cholecystectomy.
- Trial name
- NCT01542697
- Testing
- intraperitoneal nebulisation of magnesium sulphate
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- B.P. Koirala Institute of Health Sciences