Clinical trials: Postoperative Pulmonary Complication
Postoperative Atelectasis, Pulmonary Atelectasis
Fresh Gas Flow and Lung Ultrasonography in Laparoscopic Cholecystectomy
This prospective randomized clinical trial aims to evaluate the effects of different fresh gas flow rates on postoperative pulmonary aeration using lung ultrasonography in patients undergoing elective laparoscopic…
- Trial name
- NCT07753278
- Testing
- Low Fresh Gas Flow (0.5 L/min), High Fresh Gas Flow (4 L/min)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Adiyaman University
Pulmonary Complication, Cardiac Surgery
Ulinastatin Reduces Postoperative Pulmonary Complications in Cardiac Surgery
This study investigates the association between intraoperative ulinastatin administration and PPCs incidence in cardiac surgery.
- Trial name
- NCT07237243
- Where
- China
- Volunteers
- 4,540 people
- Sponsor
- Qin Zhang
Thoracic Diseases
Mechanical Insufflator-exsufflator in Patients After Video-assisted Thoracoscopic Operations With One-lung Ventilation
Postoperative pulmonary complications (PPC) are a common problem in patients undergoing surgery using one-lung invasive ventilation.
- Trial name
- NCT06180148
- Testing
- Mechanical insufflator-exsufflator
- Where
- Russia
- Volunteers
- 31 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Respiratory Complication, Respiration, Artificial
Ventilation in Cardiac Surgery
The purpose of this study is to evaluate prospectively ventilatory practices in the perioperative cardiac surgery period.
- Conditions
- Respiratory Complication, Respiration, Artificial, Anesthesia, General, Bypass, Cardiopulmonary
- Trial name
- VENICE (NCT03255356)
- Testing
- Survey
- Where
- 10 sites in Belgium, Brazil and 8 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Caen
Cardiac Surgical Procedures (Postoperative Population), Critical Illness
BIS in ICU Interventional Study
This study will test whether using a Bispectral Index (BIS) monitor to guide sedation can reduce the amount of sedative medication given to adults in the intensive care unit (ICU) after cardiac surgery.
- Conditions
- Cardiac Surgical Procedures (Postoperative Population), Critical Illness, Postoperative Complications (Cardiopulmonary), Delirium - Postoperative
- Trial name
- NCT07350122
- Testing
- Device-guided sedation, standard sedation practice
- Volunteers
- 144 people
- Sponsor
- Medical University of Graz
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Surgery--Complications, Atelectasis
The Incidence of Postoperative Pulmonary Complications in Patients With a Positive and Negative AIR-Test During General Anesthesia
The overall objective of this study is to describe the incidence of postoperative pulmonary complications in patients with a positive and negative AIR-test result.
- Conditions
- Surgery--Complications, Atelectasis, Anesthesia
- Trial name
- NCT05345743
- Testing
- Surgery
- Where
- Netherlands
- Volunteers
- 632 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Incisional Hernia, Recurrent Hernia
Pulmonary Ventilation Function Between Patients With Primary and Recurrent Incisional Hernia: a Cross-sectional Study
Purpose Chronic obstructive pulmonary disease (COPD) is a risk factor for incisional hernia, COPD has persistent airflow restriction and pulmonary ventilation dysfunction.
- Conditions
- Incisional Hernia, Recurrent Hernia, COPD, Pulmonary Ventilation Function
- Trial name
- NCT05991024
- Testing
- the incisional hernia recurrent
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Fudan University
Cardiac Arrest, Post Cardiac Arrest Syndrome
Lung-cOnservative Liquid VEntilation for the Induction of Ultra-Rapid COOLing After Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) affects over 356,000 individuals annually in the United States, with fewer than 10% surviving to hospital discharge, mirroring statistics from Europe.
- Trial name
- OverCool (NCT06798818)
- Testing
- Ultra-rapid therapeutic hypothermia induction by total liquid ventilation
- Where
- France
- Volunteers
- 24 people
- Sponsor
- ORIXHA
Postoperative Pulmonary Complications
Analysis of Risk Factors and Establishment of Early Warning Model for Pulmonary Complications
The purpose of this study is to collect perioperative diagnosis and treatment information for cardiac surgery patients, collect blood samples for laboratory testing when necessary, and analyze the data to clarify the risk factors…
- Trial name
- NCT04967651
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Postoperative Complications, Pulmonary Complication
Perioperative Oral Decontamination and ImmunoNuTrition (POINT) in Elderly
The goal of this multicenter randomized controlled trial is to explore the efficacy of perioperative oral decontamination and immunonutrition supplement to prevent postoperative pulmonary complications in elderly patients(≥65…
- Trial name
- POINT (NCT05971810)
- Testing
- immunonutrition supplement of ORAL IMPACT™, oral chlorhexidine decontamination
- Where
- 2 sites in China
- Volunteers
- 592 people
- Sponsor
- Peking Union Medical College Hospital
Lung Surgery
Ventilation Strategies Impact on Oxygenation and Postoperative Pulmonary Complications in Lung Surgery Patients
The purpose of this clinical trial was to understand the effects of variable tidal volume ventilation (V-VCV), pressure-regulated volume-controlled ventilation (PRVC), conventional volume-controlled ventilation (C-VCV)…
- Trial name
- NCT06805760
- Testing
- variable tidal volume ventilation (V-VCV), pressure-regulated volume-controlled ventilation (PRVC), conventional volume-controlled ventilation (C-VCV)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Inner Mongolia Baogang Hospital
Pulmonary Atelectasis, Morbid Obesity
Use of Airway Pressure Release Ventilation in Morbidly Obese Patients Undergoing Open Heart Surgery
The goal of this Randomized Clinical trial is to to investigate if the use of Air Pressure Release Ventilation in morbidly obese patients undergoing open heart surgery will improve post operative pulmonary outcomes 60 Patients…
- Conditions
- Pulmonary Atelectasis, Morbid Obesity, Pulmonary Complication
- Trial name
- NCT05670483
- Testing
- Use Of APRV mode of Ventilation, Use of conventional Synchronized Intermittent Mandatory Ventilation (SIMV) volume control mode
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Complication of Ventilation Therapy, Intubation Complication
Bronchial Blocker for One-lung Ventilation in Cardiac Surgery
To investigate if bronchial blocker is more suitable for one-lung ventilation during thoracoscope assisted mitral valve replacement surgery with Cardiopulmonary Bypass than the double-lumen endobronchial tube.
- Conditions
- Complication of Ventilation Therapy, Intubation Complication, Postoperative; Dysfunction Following Cardiac Surgery
- Trial name
- NCT02729610
- Testing
- double-lumen endotracheal tube (DLT group), endobronchial blocker (BB group)
- Volunteers
- 58 people
- Sponsor
- Xijing Hospital
Venous Thromboembolism, Bleeding
Avoiding Risks of Thrombosis and Bleeding in Surgery (ARTS) Trial
Avoiding Risks of Thrombosis and bleeding in Surgery (ARTS) trial is a pragmatic, international, multicenter, randomized controlled open label trial comparing a direct oral anticoagulant (DOAC) - oral factor Xa inhibitor apixaban…
- Trial name
- ARTS (NCT06523959)
- Testing
- Apixaban 2.5 MG
- Where
- Finland
- Volunteers
- 5,436 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Postoperative Pulmonary Complications (PPC)
Mechanical Power-Integrated Oxygenation Indices for Predicting Postoperative Pulmonary Complications After Major Abdominal Surgery
The goal of this prospective observational study is to determine whether novel oxygenation and oxygen saturation indices that incorporate total or dynamic mechanical power can predict postoperative pulmonary complications (PPCs)…
- Trial name
- NCT07788313
- Testing
- No Interventions
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Hadeer Yasser Abd El-aliem
Postoperative Pulmonary Complications, Mechanical Ventilation
Driving Pressure-Guided Individualized PEEP Versus Standard PEEP: Effects on Postoperative Pulmonary Complications in Upper Abdominal Digestive Surgery
This randomized clinical trial compares two methods of setting positive end-expiratory pressure (PEEP) during general anesthesia in adults undergoing upper abdominal digestive surgery who are at moderate or high risk of…
- Trial name
- NCT07885124
- Testing
- Driving Pressure-Guided Individualized PEEP, Standard PEEP
- Where
- Tunisia
- Volunteers
- 210 people
- Sponsor
- Hopital Charles Nicolle
Heart Valvular Disease, Coronary Arteriosclerosis
Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation
In this study, the primary aim is to compare the impact of using a double-lumen tube and bronchial blocker for single-lung ventilation in patients undergoing minimal invasive cardiac surgeries on postoperative pulmonary…
- Conditions
- Heart Valvular Disease, Coronary Arteriosclerosis, One-lung Ventilation
- Trial name
- NCT06299735
- Testing
- Minimally Invasive Cardiac Surgery (airway management with double-lumen tube), Minimally Invasive Cardiac Surgery (airway management with endobronchial blocker)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lung Cancer, Robotic Thoracic Surgery
Impact of Robotic Approach Compared to VATS and Open Approach on Quality of Life in Patients With Lung Cancer
The aim of the study is to compare quality of life and early and late post-operative pain after anatomical lung resection (lobectomy or segmentectomy) performed by a robotic approach compared to the videothoracoscopic approach…
- Conditions
- Lung Cancer, Robotic Thoracic Surgery, Video-assisted Thoracis Surgery (VATS), Open Thoracotomy Surgery
- Trial name
- QoL (NCT04353349)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Clinico Humanitas
Lung Transplant; Complications, Acute Kidney Injury
Association Between Renal Regional Oxygen Saturation Measured by Near-InfraRed Spectroscopy and Postoperative Renal Failure After Lung Transplantation Surgery: A Pilot Study
Complications after lung transplantation are almost ubiquitous, among which postoperative acute renal failure may represent more than 50% of lung transplant patients and require extrarenal purification in 5 to 13% of cases.
- Trial name
- SO-AKI-TP (NCT05836922)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique Hopitaux De Marseille