Clinical trials: Postoperative Pulmonary Complication
Endotracheal Intubation, Robotic Esophagectomy
The Association of Intraoperative Oxygen Reserve Index and Postoperative Pulmonary Complications in Robot-assisted Esophagectomy
The World Health Organization (WHO) has proposed the use of 80% high-dose inhalation oxygen (FiO2) during surgery to reduce postoperative infection in adult patients undergoing general anesthesia.
- Conditions
- Endotracheal Intubation, Robotic Esophagectomy, Esophagectomy
- Trial name
- NCT04008420
- Testing
- monitoring of the oxygen reserve index
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
Ischemic Heart Disease, Post-Operative Complications
On-Pump vs. Off-Pump CABG in High-Risk Patients (EuroSCORE 6+)
Previous studies comparing on-pump and off-pump operating strategy did only partially demonstrate benefits of the off-pump myocardial revascularisation.In primary end-points (MI, death, renal failure, and so on) there was no…
- Trial name
- PRAGUE 6+ (NCT00606372)
- Testing
- OPCAB - the off-pump coronary artery bypass
- Where
- 2 sites in Czechia
- Volunteers
- 220 people
- Sponsor
- Charles University, Czech Republic
Pain, Postoperative, Lung Diseases
Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection
This is a single center, single surgeon, prospective, randomized trial examining the addition of Cryo Nerve Block during robot assisted thoracoscopic anatomic lung resection surgery
- Trial name
- NCT05144828
- Testing
- Intercostal Nerve Cryoablation, Patient-controlled analgesia (PCA)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Medical College of Wisconsin
Other Complications of Esophagostomy
Outcome Study of Restrictive vs. Liberal Intraoperative Fluid Management Guided by PPV in Esophagectomy
The purpose of this study is to determine whether intraoperative restrictive fluid management guided by pulse pressure variation produces a better effect on the postoperative lung function, kidney function, inflammatory response…
- Trial name
- PPV (NCT01933451)
- Testing
- Intraoperative fluid therapy
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- National Taiwan University Hospital
Postoperative Pulmonary Atelectasis, Surgery
Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27)
The purpose of this study is to determine whether prophylactic nasal continuous positive airway pressure (nCPAP) in the post-anaesthesia care unit (PACU) improves post-operative pulmonary function following elective bowel…
- Trial name
- NCT01316575
- Testing
- nCPAP, Low Flow Oxygen
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Esophageal Neoplasm
Lung Ultrasound in the Early Detection of Postoperative Pulmonary Complications After Esophagectomy
The perioperative management of esophageal cancer has evolved considerably in recent years. Over the last 30 years, postoperative mortality has been steadily decreasing. However, respiratory morbidity remains high (30-40%).
- Trial name
- OESOLUS (NCT05453760)
- Where
- France
- Volunteers
- 274 people
- Sponsor
- University Hospital, Lille
Lung Injury, Pulmonary Complication
Intraoperative Mechanical Power and Ventilation-Associated Lung Injury: Assessing Complications
This study investigates the relationship between intraoperative mechanical power and postoperative pulmonary complications in patients undergoing major abdominal surgery.
- Trial name
- NCT06375980
- Testing
- Intraoperative Mechanical Ventilation Strategies
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy
Postoperative pain remains relatively high within 48h for Chinese patients who receive video-assisted thoracoscopic surgery. Multimodal analgesia combines several agents and/or techniques to function on diverse nociceptive…
- Trial name
- NCT03648008
- Testing
- Hydromorphone, Morphine
- Where
- China
- Volunteers
- 171 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Pulmonary Complications (PPCs), Postoperative Atelectasis
Optimal PEEP Level for Minimizing the Risk of Postoperative Atelectasis: A Retrospective Cohort Study Based on Lung Ultrasound Monitoring
Background: After surgery with general anesthesia, it is common for parts of the lungs to collapse, a condition called atelectasis. This can lead to low blood oxygen levels and other lung complications.
- Conditions
- Postoperative Pulmonary Complications (PPCs), Postoperative Atelectasis, Lung Ultrasound
- Trial name
- ULTRASVENT-1 (NCT07211074)
- Where
- Russia
- Volunteers
- 450 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Postoperative Pulmonary Complications
An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study
Postoperative pulmonary complications (PPCs) are a major cause of morbidity and mortality in surgical patients. National estimates suggest 1,062,000 PPCs per year, with 46,200 deaths, and 4.8 million additional days of…
- Trial name
- PRIME-AIR (NCT04108130)
- Testing
- Preoperative Education, Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization, Individualization of Neuromuscular Blockade
- Where
- 16 sites in United States
- Volunteers
- 794 people
- Sponsor
- Columbia University
Atrial Fibrillation, Lung Cancer
Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection
Atrial fibrillation is a very common complication of pulmonary resection. Patients who develop atrial fibrillation require additional treatment and are more likely to stay in the hospital for longer period of time increasing the…
- Trial name
- NCT00300495
- Testing
- Amiodarone, Control arm, standard care
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Beth Israel Deaconess Medical Center
Surgery, Mechanical Ventilation Complication
Re-Evaluation of the Effects of High PEEP During General Anesthesia For Surgery (REPEAT)
Aiming to understand the isolated impact of high PEEP in patients undergoing mechanical ventilation for general anesthesia for surgery, three appropriately sized international multicentre randomized controlled trials have been…
- Conditions
- Surgery, Mechanical Ventilation Complication, Pulmonary Complication
- Trial name
- REPEAT (NCT03937375)
- Testing
- High PEEP, Low PEEP
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 3,837 people
- Sponsor
- Hospital Israelita Albert Einstein
Perioperative Complication, Nursing Caries
The Effects of Listening Music During Breathing Exercises
Background and purpose : This study aims to analyze the effects of listening to music during deep breathing and coughing exercises on vital sings and pulmonary functions in patients, who underwent video assisted thoracoscopic…
- Conditions
- Perioperative Complication, Nursing Caries, Pain, Postoperative
- Trial name
- NCT05329519
- Testing
- Listening music
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Lung Cancer, Postoperative Pulmonary Complications
Structured Pulmonary Physiotherapy After Lung Cancer Surgery by Age Group
This ambispective observational cohort study aims to evaluate age-related differences in clinical outcomes among patients undergoing lung cancer surgery who received a structured comprehensive in-patient physiotherapy (CIPT)…
- Trial name
- NCT07441863
- Testing
- Comprehensive In-Patient Physiotherapy (CIPT) Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Diaphragm Issues, Neurosurgery
Post-neurosurgical Respiratory Muscle Dysfunction
Respiratory muscle dysfunction may contribute to the development of postoperative pulmonary complications. However, it prevalence in patients receiving neurosurgery is largely unknown.
- Conditions
- Diaphragm Issues, Neurosurgery, Pulmonary Complication
- Trial name
- NCT05951114
- Testing
- Maximum inspiratory/Expiratory manoeuvre for patients can follow the order
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Sanbo Brain Hospital
Abdominal Surgery
Effects of ACBT and Blow Bottle Technique in Patients With Abdominal Surgeries Under General Anesthesia
A postoperative pulmonary complication (PPC) is the most common serious complication after Abdominal surgery under GA which lead to longer hospital stays and have deleterious outcomes on lung volumes, mucociliary clearance…
- Trial name
- NCT06454305
- Testing
- Active cycle of breathing technique, Blow Bottle Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Postoperative Complications
Use of Integrated Pulmonary Index to Predict Post-Operative Respiratory Adverse Events in High Risk Patients
The Capnostream 20p monitor by Medtronic is FDA-cleared and consists of a monitor which measures real-time respiratory status based on respiratory rate, pulse rate, pulse oximetry (SpO2) and end tidal carbon dioxide (etCO2) with…
- Trial name
- NCT03275324
- Testing
- Capnostream20p
- Volunteers
- 600 people
- Sponsor
- Stony Brook University
PostoperativePulmonaryComplications
A Multicenter Randomized Controlled Clinical Trial of the Impact of Minimally Invasive Abdominal Surgery Esophageal Pressure Monitoring Guided Individualized PEEP on Postoperative Pulmonary Complications in Obese Patients
The aim of this study is to compare the effect of individualized PEEP based on transmural lung pressure and fixed PEEP on postoperative pulmonary complications during laparoscopic or robotic abdominal surgery in obese patients.
- Trial name
- NCT06996288
- Testing
- Transpulmonary pressure-guided individualized PEEP
- Volunteers
- 180 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Lung Transplant Infection, Lower Respiratory Tract Infection
Preliminary Study of Dornase Alfa to Treat Chest Infections Post Lung Transplant.
Patients who have undergone lung transplantation are at an increased risk of developing chest infections due to long-term medication suppressing the immune response.
- Trial name
- NCT01952470
- Testing
- Dornase Alfa, Isotonic Saline.
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- The Alfred