Clinical trials: Postoperative Pulmonary Dysfunction
Diaphragm Issues, Neurosurgery
Post-neurosurgical Respiratory Muscle Dysfunction
Respiratory muscle dysfunction may contribute to the development of postoperative pulmonary complications. However, it prevalence in patients receiving neurosurgery is largely unknown.
- Conditions
- Diaphragm Issues, Neurosurgery, Pulmonary Complication
- Trial name
- NCT05951114
- Testing
- Maximum inspiratory/Expiratory manoeuvre for patients can follow the order
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Sanbo Brain Hospital
Lung Transplantation
Point-of-care Management of Coagulopathy in Lung Transplantation
Pulmonary transplantation is a very demanding surgical procedure, often accompanied by coagulopathy and severe perioperative bleeding.
- Trial name
- NCT03598907
- Testing
- Fresh frozen plasma
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital, Motol
Lung Transplant; Complications, Primary Graft Dysfunction
Identifying Optimal PEEP After Lung Transplantation
Lung Transplantation (LuTX) is the curative treatment for selected patients with end-stage lung disease. Primary Graft Dysfunction (PGD), a specific form of respiratory failure occurring within the first 72 hours after graft…
- Trial name
- PEEP-LuTX (NCT05691205)
- Testing
- PEEP
- Where
- Italy
- Volunteers
- 47 people
- Sponsor
- Policlinico Hospital
Diaphragmatic Dysfunction
Comparative Ultrasonic Study of Post Operative Diaphragmatic Dysfunction in Abdominal and Head and Neck Surgery
Diaphragmatic dysfunction (DD) is one of the main risk factors for post operative respiratory distress syndrome. Ultrasonography is a diagnosis tool for DD but few studies have been published.
- Trial name
- Under the Dome (NCT01737775)
- Testing
- Diaphragmatic amplitude measurement
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Lung Transplantation, Primary Graft Dysfunction
The Use of Surfactant in Lung Transplantation: A Randomized Control Pilot Study
1. Working Hypothesis: The purpose of the trial is to study the effect of exogenous calf surfactant (calfactant) on the prevention of primary graft failure due to ischemic-reperfusion lung injury in lung transplant patients. 2.
- Trial name
- NCT00506532
- Testing
- Surfactant (calfactant)
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Rabin Medical Center
Diaphragm Injury, Phrenic Nerve Paralysis
Measurement of Diaphragmatic Dysfunction After Thoracic Surgery
This study aims to measure diaphragmatic dysfunction with ultrasonography and nerve stimulation of the phrenicus nerve, in patients undergoing thoracic surgery for lung and esophageal cancer, and correlate measures of…
- Conditions
- Diaphragm Injury, Phrenic Nerve Paralysis, Thoracic Cancer, Postoperative Complications
- Trial name
- NCT04507594
- Testing
- Lung lobectomy OR esophagus cancer resection
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aarhus University Hospital
Lung Transplantation
Lung and Diaphragm Ultrasound in the Early Postoperative Course Following Lung Transplantation
This feasibility study tries to define the value of daily Lung and Diaphragm Ultrasound in the early postoperative course following Lung transplantation by comparing its diagnostic accuracy with that of standard of care…
- Trial name
- LUS (NCT04891094)
- Testing
- Ultrasound
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Primary Graft Dysfunction, Lung Transplantation
Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation
Primary graft dysfunction (PGD) is a severe lung complication that can occur in the days after lung transplant surgery. This study will analyze blood samples to determine if high levels of certain chemicals may increase the risk…
- Trial name
- NCT00552357
- Where
- United States
- Volunteers
- 1,150 people
- Sponsor
- University of Pennsylvania
Lung Transplant
Intraoperative Versus Postoperative Thymoglobulin in Lung Transplantation
The purpose of this study is to take a population of lung transplant recipients who meet UCLA criteria for induction chemotherapy with thymoglobulin and prospectively study weather giving the first dose intraoperatively versus…
- Trial name
- NCT00592306
- Testing
- thymoglobulin (intraoperative), thymoglobulin (postoperative)
- Where
- United States
- Sponsor
- University of California, Los Angeles