Clinical trials: Postoperative Recovery After Cardiac Surgery
Post-cardiac Surgery
Dexmedetomidine Enhancing the Recovery After Cardiac Surgery
Enhanced Recovery After Surgery (ERAS) aims to facilitate a quicker and smoother recovery period following surgical procedures. The implementation of these protocols may lead to patients returning to their daily activities…
- Trial name
- NCT06907277
- Testing
- Dexmedetomidine, Fentanyl, Lidocain
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
Colectomy, Colectomy Left/Right/Total Under Laparotomy
Clinical Study on the Prevention and Treatment of Postoperative Gastrointestinal Dysfunction by Acupuncture Under ERAS Management Based on Artificial Intelligence Monitoring
Brief Summary: Acupuncture for Faster Recovery After Colorectal Surgery 1. What is this study about? Colorectal cancer is a common health condition that usually requires surgery.
- Conditions
- Colectomy, Colectomy Left/Right/Total Under Laparotomy, Cancer, Chinese Medicine
- Trial name
- NCT07335237
- Testing
- Accupuncture
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jiangsu Province Hospital of Traditional Chinese Medicine
Postoperative Quality of Recovery
Validation of the German Quality of Recovery-15 Questionnaire
The Quality of Recovery 15-questionnaire (QoR-15) is used to assess postoperative quality of recovery after surgery and anesthesia from the patient's perspective.
- Trial name
- NCT04528524
- Testing
- Questionnaire
- Where
- Germany
- Volunteers
- 186 people
- Sponsor
- Marlene Fischer
Surgery Stress
The Effects of Erector Spinae Plane (ESP) Block on Surgery-related Stress Response in Cardiac Surgery With ERAS
Surgery-induced pain reveals its own metabolic and inflammatory responses, resulting in a further increase in noxious pathways that are already occurring.
- Trial name
- NCT04924335
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Enhanced Recovery After Surgery, Quality Improvement
Study to Evaluate the Impact of the Recovery Pathway on Postoperative Leght of Stay in Coronary Artery Bypass Surgery
This randomized and prospective trial aims to evaluate the implementation of a rapid recovery protocol for coronary artery bypass grafting (CABG) in a hospital serving patients from the Brazilian Unified Health System (Sistema…
- Trial name
- KAMAY (NCT06713096)
- Testing
- Tempos Certos protocol
- Where
- Brazil
- Volunteers
- 128 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease
Topical Application of Tranexamic Acid to Reduce Post-operative Bleeding in Coronary Artery Bypass Surgery
The goal of this project is to determine whether the use of tranexamic acid, a clot-promoting drug, applied topically over the heart in coronary artery bypass graft surgery (CABG) will reduce post operative blood loss.
- Trial name
- NCT01519245
- Testing
- Tranexamic Acid, normal saline
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Postoperative Atrial Fibrillation
Quality of Life in Patients With Postoperative Atrial Fibrillation After Cardiac Surgery
Prospective observational study on quality of life with postoperative atrial fibrillation after cardiac surgery using SF-36 and qualitative questions
- Trial name
- NCT07173998
- Testing
- Survey
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Brigham and Women's Hospital
ERAS, Cardiac Surgery
Impact of a Technology Platform Based on Enhanced Recovery After(ERAS) Surgery on Length of Stay After Coronary Artery Bypass Grafting: Timely Project
Cardiovascular diseases continue to be the leading cause of death worldwide. Among them, coronary artery disease has the greatest impact, being characterized as one of the main causes of death in Brazil over the last decade.
- Conditions
- ERAS, Cardiac Surgery, Cardiac Surgery-CABG, Digital Health
- Trial name
- REPLICCARIII (NCT06786819)
- Testing
- ERACS with Digital Platform
- Where
- 2 sites in Brazil
- Volunteers
- 480 people
- Sponsor
- University of Sao Paulo General Hospital
Postoperative Recovery, Length of Hospital Stay
The Effect of the Anticholinergic Burden Following Elective Coronary Artery Surgery
Anticholinergic drugs are common in older adults and linked to cognitive decline, frailty, longer hospital stay, and higher mortality.
- Conditions
- Postoperative Recovery, Length of Hospital Stay, Postoperative Complications
- Trial name
- NCT06349057
- Testing
- reducing anticholinergic burden
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Cognitive Dysfunction
Evaluation of Blood Biomarkers as an Indicator of Delayed Neurocognitive Recovery
Delayed neurocognitive recovery is defined as a cognitive decline arising after surgery. In the present study, the authors evaluate the level of D-Amino Acid Oxidase, D-serine and Serine racemase in blood as an indicator of…
- Trial name
- NCT04679259
- Testing
- Blood sampling for assessment of the level of D-Amino Acid Oxidase, D-serine and Serine in blood, Neurocognitive test, Assessment of delirium
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- SMG-SNU Boramae Medical Center
Coronary Artery Bypass Graft Surgery, Valve Replacement
Inspiratory Muscle Training Prior to Conventional and Minimal Invasive Heart Surgery
The main objective of this study is to evaluate the effect of pre-operative Inspiratory muscle training (IMT) using an IMT Threshold device (Philips), on early postoperative lung function recovery and on the occurrence of…
- Conditions
- Coronary Artery Bypass Graft Surgery, Valve Replacement, Post-Op Complications, Physiotherapy
- Trial name
- PRIMUS (NCT04717817)
- Testing
- Inspiratory muscle training (IMT) using an IMT Threshold device (Philips), Standard physiotherapy
- Sponsor
- Universitair Ziekenhuis Brussel
Coronary Artery Disease, Pain Syndrome
Effect of Bilateral Transversus Thoracis Muscle Plane Block in Patients Undergoing Coronary Artery Bypass Graft Surgery.
Coronary artery bypass graft surgery is the standard surgical treatment for coronary disease. However, there is no consensus on analgesic management in patients undergoing CABG.
- Trial name
- PARACABS (NCT04849117)
- Testing
- Ultrasound guided Bilateral Transversus Thoracis Muscle Plane block
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Delirium, Cognitive Decline
Dexmedetomidine Use in ICU Sedation and Postoperative Recovery in Elderly Patients and Post-cardiac Surgery
Increasing numbers of elderly patients are undergoing cardiac surgery. Elderly patients may have prolonged recovery following cardiac surgery when compared to other groups of patients, and are at higher risk of postoperative…
- Conditions
- Delirium, Cognitive Decline, Post-operative Quality of Recovery
- Trial name
- DIRECT (NCT02699801)
- Testing
- propofol, Dexmedetomidine
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of British Columbia
Postoperative Pain
Pecto-intercostal Fascial Plane Block for Postoperative Analgesia and Recovery Profile After Off-Pump Coronary Artery Bypass Surgery
Moderate to severe postoperative pain is usually encountered after cardiac surgery.Improper postoperative pain control could have multiple hemodynamic hazards in addition to prolonged postoperative ventilatory support and…
- Trial name
- NCT05774249
- Testing
- Ultrasound guided pecto-intercostal Fascial Plane Block using bupivacaine, Ultrasound guided pecto-intercostal Fascial Plane Block using normal saline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Cardiovascular Disease
Remifentanil Anesthesia and Postoperative BIS in Cardiac Surgery
Background: Although remifentanil based anesthesia has been preferred for fast-track cardiac anesthesia, its recovery profile in cognitive function has not been investigated.
- Trial name
- NCT02400879
- Testing
- Remifentanil, sevoflurane and sufentanil
- Volunteers
- 38 people
- Sponsor
- Konkuk University Medical Center
Postoperative; Dysfunction Following Cardiac Surgery
My Cardiac Recovery (MyCaRe): A Pilot RCT.
MyCardiacRecovery (MyCaRe) is an interactive platform that includes a standardized educational format and interactive tracking (wound healing and activity progression using photo capabilities and Fitbit Inspire 2 accelerometer)…
- Trial name
- MyCaRe (NCT02778165)
- Testing
- MyCaRe (my cardiac recovery Android application)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Ventilator-Induced Diaphragm Dysfunction
Study of TransAeris® System for Enhanced Recovery After Surgery in France
This study will be conducted as a randomized trial of the TransAeris system for the prevention and treatment of ventilator-induced diaphragm dysfunction (VIDD) in patients identified prior to surgery to be at greater risk of…
- Trial name
- ERAS (NCT05404477)
- Testing
- TransAeris System
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Synapse Biomedical
Right Ventricular Function, Prone Position
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay.
- Conditions
- Right Ventricular Function, Prone Position, Atelectasis, Atelectases, Postoperative Pulmonary
- Trial name
- BAROLO (NCT07632027)
- Testing
- Prone position
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Left Ventricular Dysfunction, Quality of Recovery
Preoperative Maltodextrin's Effect on Cardiac Function in Cardiac Surgery
A randomized, controlled, double-blinded clinical trial evaluating the effect of the administration of a Maltodextrin solution on cardiac function in patients presenting for coronary artery bypass grafting surgery with a reduced…
- Conditions
- Left Ventricular Dysfunction, Quality of Recovery, Right Ventricular Dysfunction
- Trial name
- NCT05188222
- Testing
- Maltodextrin solution
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Jewish General Hospital
Congenital Heart Disease, Total Cavo-pulmonary Connection
Impact of Nesiritide on Early Postoperative Recovery After Total Cavo-Pulmonary Connection Surgery in Children
Nesiritide, a recombinant human B-type natriuretic peptide, has favorable effects on patient symptoms, hemodynamics, and the neurohumoral profile in adults with decompensated congestive heart failure and in those recovering from…
- Trial name
- NCT03207295
- Testing
- Nesiritide, Normal saline
- Where
- China
- Volunteers
- 108 people
- Sponsor
- China National Center for Cardiovascular Diseases