Clinical trials: Postoperative Renal Complication
Postoperative Pain, Analgesia
Application of Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament Under Laparoscopic Direct Vision in Laparoscopic Renal Surgery
Evaluation of the effectiveness of Anterior Quadratus Lumborum Block at the lateral supra-arcuate ligament under laparoscopic direct vision compared to local infiltration anesthesia for postoperative analgesia after laparoscopic…
- Conditions
- Postoperative Pain, Analgesia, Quadratus Lumborum Block, Laparoscopic Renal Surgery
- Trial name
- NCT06550869
- Testing
- Anterior Quadratus Lumborum Block at the lateral supra-arcuate ligament under laparoscopic direct vision, Local infiltration anesthesia
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Kidney Injury (Nontraumatic), Hypotension Drug-Induced
AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia
This project investigates intentionally hypotensive management such as NTG (nitroglycerin) or NTG+Trandate during general anesthesia in patients undergoing orthognathic surgery.
- Trial name
- NCT06259760
- Testing
- Nitroglycerin
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Kidney Transplantation
Does an Abdominal Wall Nerve Block During Surgery Help Reduce Pain From Kidney Transplantation?
This is a randomized, placebo controlled, double blind study to determine the effectiveness of a Transversus Abdominis Plane (TAP) block for reducing postoperative pain and opioid use in kidney transplant recipients.
- Trial name
- NCT05280197
- Testing
- TAP block, liposomal bupivacaine plus free bupivacaine, normal saline
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- The Cleveland Clinic
Nephrolithiasis, Urolithiasis
Perioperative Pregabalin in Ureteroscopy: a Pilot
The investigators propose a pilot clinical trial on the use of perioperative pregabalin in order to decrease ureteral stent related symptoms and decrease opioid usage after ureteroscopy with stent placement.
- Conditions
- Nephrolithiasis, Urolithiasis, Perioperative/Postoperative Complications, Pain, Postoperative
- Trial name
- NCT03927781
- Testing
- Pregabalin 300mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Nephrolithiasis
Postoperative Analgesia Practices After Percutaneous Nephrolithotomy
This prospective observational study aims to evaluate the effectiveness and safety of different postoperative analgesia methods used in patients undergoing percutaneous nephrolithotomy (PCNL).
- Trial name
- NCT07258901
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istinye University
Liver Transplantation, Postoperative Renal Complication
Postoperative Complications After Liver Transplantation
Incidence and risk factors for renal, cardiovascular and pulmonary complications after liver transplantation are not well defined.
- Conditions
- Liver Transplantation, Postoperative Renal Complication, Postoperative Pulmonary Complication, Postoperative Cardiovascular Complication
- Trial name
- NCT02761109
- Where
- Italy
- Volunteers
- 1,600 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Acute Kidney Injury, Cardiac
Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery: a Retrospective Monocentric Cohort Study
Cardiac surgery with cardiopulmonary bypass exposes patients to the risk of post-operative acute kidney injury. In the specific setting of cardiac surgery, acute kidney injury is often of multifactorial origindue to particular…
- Conditions
- Acute Kidney Injury, Cardiac, Surgery
- Trial name
- SGLT2i (NCT06453161)
- Testing
- Post-operative acute kidney injury
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Injury (AKI), Coronary Artery Bypass Graft (CABG)
Effect of Cardiovascular Autonomic Neuropathy on AKI and Outcomes in Isolated CABG Surgery
This study aims to investigate the effects of Cardiovascular Autonomic Neuropathy (CAN) on Acute Kidney Injury (AKI) and clinical outcomes in patients undergoing isolated Coronary Artery Bypass Graft (CABG) surgery requiring…
- Conditions
- Acute Kidney Injury (AKI), Coronary Artery Bypass Graft (CABG), Cardiovascular Autonomic Neuropathy (CAN), Postoperative Outcomes
- Trial name
- CAN-AKI-CABG (NCT07254468)
- Where
- Turkey (Türkiye)
- Volunteers
- 912 people
- Sponsor
- Akdeniz University
Clear Cell Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v7
Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery
This randomized phase III trial studies how well pazopanib hydrochloride works compared to placebo in treating patients with kidney cancer that has spread to other parts of the body and have no evidence of disease after surgery.
- Trial name
- NCT01575548
- Testing
- Computed Tomography, Magnetic Resonance Imaging, Pazopanib Hydrochloride
- Where
- 579 sites in United States
- Volunteers
- 129 people
- Sponsor
- National Cancer Institute (NCI)
Kidney Cancer
Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery.
- Trial name
- NCT00047138
- Testing
- dactinomycin, carboplatin, cyclophosphamide
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 350 people
- Sponsor
- University of Leicester
Ischemia-reperfusion Injury, Kidney Transplant; Complications
A Trial to Assess Efficacy and Safety of ex Vivo Allograft Admin of iCM012 Solution 2 mg/ml to Improve Its Function in Recipients of DCD Kidneys
Randomized (1:1), placebo controlled, double blind efficacy trial. 200 patients will be followed up for 12 months post transplantation.
- Trial name
- NCT06582485
- Testing
- iCM012 solution 2 mg/mL
- Volunteers
- 200 people
- Sponsor
- iCoat Medical AB
Acute Kidney Injury
Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI
Acute kidney injury (AKI) occurs in up to 30% of patients undergoing coronary artery bypass graft (CABG) surgery, and often requires patients to go on dialysis.
- Trial name
- NCT03810417
- Testing
- Digoxin Antibodies Fab Fragments, Baseline EO > 360 pM, EO < 360 pM
- Where
- 2 sites in United States
- Volunteers
- 267 people
- Sponsor
- University of Maryland, Baltimore
Acute Kidney Injury
Renal Oximetry-Guided Anesthesia With Near-Infrared Spectroscopy for Improved Postoperative Outcomes
The trial is a prospective, randomized, single-blind, pilot study investigating whether near-infrared spectroscopy (NIRS)-guided optimization of intraoperative renal oxygen saturation reduces postoperative acute kidney injury…
- Trial name
- ROGAR (NCT07141693)
- Testing
- NIRS-guided management, Standard anesthesia management
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Cardiac Anaesthesia
Cardiac Anesthesia Registry Including Biosignal Database for Prognostication of Postoperative Renal Outcome
AKI(Acute Kidney Injury) is a common complication after cardiac surgery which is associated with increased mortality and morbidity.
- Trial name
- NCT06581289
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Yonsei University
Nephrolithiasis
Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain
Post-operative pain and lower urinary tract symptoms are common following ureteroscopy in the treatment of stone disease. The use of bupivacaine as a topical pain medication is used routinely for other urologic procedures…
- Trial name
- NCT06635889
- Testing
- Bupivacaine, Normal saline
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pain, Postoperative
Erector Spinae Plane Block for Post-nephrectomy Pain
Acute postoperative pain proper management is important not only for patient satisfaction but also for patient outcome. It may also predispose patients to chronic post-surgical pain .Open nephrectomy is still conducted, although…
- Trial name
- NCT04537598
- Testing
- Morphine patient controlled analgesia, Erector Spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Impaired Cognition, Quality of Life
The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery
The primary aim of this study is to establish if it is possible for patients who have undergone major body surgery to complete a home based exercise training program and complete the assessments required to measure physical and…
- Conditions
- Impaired Cognition, Quality of Life, Surgery, Delirium
- Trial name
- POETold (NCT03064308)
- Testing
- Exercise Programme
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Nottingham
Renal Tumor
A Comparison of Nefopam-propacetamol Combination and Propacetamol for Postoperative Quality of Recovery After Laparoscopic Nephrectomy
The multimodal analgesia for postoperative pain aims for optimal analgesia through additive or synergic drug effects. The multimodal analgesia results in the use of smaller doses of opioids and lowering opioid-related side…
- Trial name
- NCT01833728
- Testing
- nefopam-propacetamol combination, propacetamol alone
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Yonsei University
Aortic Dissection, Acute Kidney Injury
Prediction of Postoperative Acute Kidney Injury in Patients With Acute Type A Aortic Dissection Using Cystatin C
The research aimed to predict postoperative acute kidney injury in patients with acute type A aortic dissection preliminarily by exploring the correlation of preoperative cystatin C level and incidence of postoperative acute…
- Trial name
- NCT05039814
- Testing
- postoperative acute kidney injury, none postoperative acute kidney injury
- Where
- China
- Volunteers
- 249 people
- Sponsor
- Qilu Hospital of Shandong University