Clinical trials: Postoperative Renal Function
Hydronephrosis
Clinical Significance of Supranormal Differential Renal Function in the Recovery of Hydronephrosis
The purpose of this study is to assess the clinical significance of supranormal differential renal function (DRF) in the recovery of unilateral hydronephrosis (HN) after surgery, pediatric patients who underwent pyeloplasty for…
- Trial name
- NCT01839006
- Testing
- dismembered pyeloplasty
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Acute Kidney Injury, Acute Kidney Disease
The Effect of Preoperative Biological Age on Hemodynamics and Renal Function
Background The aim of this study is to explore the potential value of preoperative biological age as a predictor of intraoperative hemodynamic changes and postoperative renal function injury.
- Conditions
- Acute Kidney Injury, Acute Kidney Disease, Intraoperative Hypotension, Post-induction Hypotension
- Trial name
- NCT07080086
- Volunteers
- 268,833 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Renal Insufficiency, Acute Kidney Injury
Influence of Perioperative Kidney Function on Postoperative Outcome
This study investigates the influence of perioperative changes in serum creatinine on hospital length of stay and mortality.
- Trial name
- NEPHRANEST (NCT01522313)
- Where
- Germany
- Volunteers
- 39,369 people
- Sponsor
- Charite University, Berlin, Germany
End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5)
Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage
The goal of this clinical trial is to test how storage temperature of deceased donor kidneys affects kidney function after transplant in adult patients receiving a kidney transplant.
- Conditions
- End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5), Kidney Transplantation Recipients
- Trial name
- NCT07385651
- Testing
- 10˚C deceased donor kidney storage using Traferox XPort
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Pulmonary Function
Post-operative Pulmonary Function After Kidney Surgery Under Two Different Techniques
To assess the respiratory and analgesic effects of continuous thoracic paravertebral block versus thoracic epidural in patients undergoing kidney surgery
- Trial name
- NCT03885583
- Testing
- thoracic epidural block, paravertebral block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Kidney Transplantation, Acute Kidney Tubular Necrosis
Effect of BM-MSCs on Early Graft Function Recovery After DCD Kidney Transplant.
This study is designed to investigate whether allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) can promote function recovery in patients with poor early graft function after kidney transplantation from Chinese…
- Trial name
- NCT02563366
- Testing
- BM-MSCs, Saline
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Renal and Urinary Disorders, Renal Cancer
Application of the "Off-Clamp And Sutureless" Technique in Robot-Assisted Partial Nephrectomy
The detection rate of renal masses smaller than 7 cm has significantly increased in recent years. To preserve postoperative renal function to the greatest extent possible, guidelines from the European Association of Urology…
- Conditions
- Renal and Urinary Disorders, Renal Cancer, Renal Particial
- Trial name
- NCT07141225
- Testing
- Off-Clamp Sutureless Technique
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Shao Pengfei
Ischemia Reperfusion Injury, Delayed Graft Function
Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation
The objectives of this study are to test the preliminary safety and efficacy of a two-day peri-operative course of treprostinil in reducing ischemia-reperfusion injury in adult patients receiving a deceased donor kidney…
- Trial name
- NCT04005469
- Testing
- Treprostinil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rhode Island Hospital
Other Complications of Esophagostomy
Outcome Study of Restrictive vs. Liberal Intraoperative Fluid Management Guided by PPV in Esophagectomy
The purpose of this study is to determine whether intraoperative restrictive fluid management guided by pulse pressure variation produces a better effect on the postoperative lung function, kidney function, inflammatory response…
- Trial name
- PPV (NCT01933451)
- Testing
- Intraoperative fluid therapy
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- National Taiwan University Hospital
Kidney Function, Kidney Transplant; Complications
Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation
Furosemide is an old drug that has been used frequently in the postoperative period of kidney transplantation, aiming to achieve adequate urine output.
- Conditions
- Kidney Function, Kidney Transplant; Complications, Delayed Graft Function
- Trial name
- FOSTIK (NCT03071536)
- Testing
- Furosemide Injection
- Where
- Thailand
- Volunteers
- 360 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Infective Endocarditis
Effect of Dexmedetomidine on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery
Acute kidney injury is major complication after open heart surgery. The cause of acute kidney injury following open heart surgery is related to activation of sympathetic nervous system, decrease of renal blood flow…
- Trial name
- NCT02698930
- Testing
- dexmedetomidine, Normal saline
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Yonsei University
Acute Renal Failure (ARF)
Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative
Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context.
- Trial name
- COVD (NCT03013621)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Delayed Graft Function, Kidney Transplant; Complications
Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys
The aim of the study is to evaluate the feasibility of this bubble and surface oxygenation and to determine the optimal timing of surface oxygenation (continuous versus intermittent) as alternative for membrane-oxygenated…
- Conditions
- Delayed Graft Function, Kidney Transplant; Complications, Ischemia Reperfusion Injury, Mitochondrial
- Trial name
- HMPO2 (NCT05430620)
- Testing
- Oxygen
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Renal Mass
Effect of Ulinastatin on Postoperative Renal Function in Patients Undergoing Robot-assisted Laparoscopic Partial Nephrectomy
Ulinastatin reduces systemic inflammatory responses and protects organs from ischemia/reperfusion-induced injury. The aim of this study is to evaluate the effect of ulinastatin on postoperative renal function in patients…
- Trial name
- NCT02258906
- Testing
- ulinastatin, normal saline
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Kidney Transplantation, Acute Kidney Tubular Necrosis
Effect of BM-MSCs in DCD Kidney Transplantation
This study is designed to determine the efficacy and safety of allogeneic bone marrow-derived mesenchymal stem cells in kidney transplantation from Chinese donation after citizen's death (DCD).
- Trial name
- NCT02561767
- Testing
- bone marrow-derived mesenchymal stem cells, Saline, Induction therapy (ATG or Basiliximab)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Aortic Aneurysm, Abdominal, Renal Insufficiency
Renal Function After Stentgraft Treatment Of Abdominal Aortic Aneurysm
This randomized controlled trial aim to determine the impact on renal function after treatment for infrarenal abdominal aortic aneurysm (AAA) with stentgrafts either with active supra- or infrarenal fixation.
- Conditions
- Aortic Aneurysm, Abdominal, Renal Insufficiency, Stent-Graft Thrombosis
- Trial name
- RENOFIX (NCT04754659)
- Testing
- Stentgraft
- Where
- Sweden
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Acute Kidney Injury
Double-Blind Placebo-Controlled CIN Trial
This double-blinded placebo-controlled study will examine the incidence and significance of contrast-induced acute kidney injury following IV iodine-based contrast material administration in subjects with stage IIIB or stage IV…
- Trial name
- NCT02467075
- Testing
- Iopamidol 300 (Contrast)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Michigan
Renal Impairment
Fluid Investigation Colloid vs Crystalloid Reg. Renal Hemodynamics and Function
Comparing the effects of crystalloid versus colloid fluid resuscitation in CABG patients postoperatively regarding renal blood flow, glomerular filtration rate and renal oxygen demand.
- Trial name
- NCT01729364
- Testing
- crystalloid, colloid
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Hypouricemia, Renal, Urolithiasis
A Randomized Clinical Trail of The Effect of Postoperative Uric Acid Control on Stone Recurrence and Renal Function in Patients With Hyperuricemia of Urolithiasis.
The purpose of this study was to explore the effects of uric acid control on stone recurrence and renal function in patients with calculi of hyperuricemia through a prospective controlled study.
- Trial name
- NCT04398251
- Testing
- Febuxostat 40mg Tab, Non-drug control group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xuhui Central Hospital, Shanghai
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram