Clinical trials: Postoperative Sleep
Postoperative Sleep Quality, General Anesthesia
The Effects of Intravenous Anesthetics and Inhaled Anesthetics on Patients' Postoperative Sleep
Adequate sleep is necessary for physical and mental health of human being. Although surgery and anesthesia techniques have improved in resent years, postoperative sleep disturbance remains a challenging problem in surgical…
- Conditions
- Postoperative Sleep Quality, General Anesthesia, Propofol, Sevoflurane
- Trial name
- NCT04123249
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Yanchao Yang
Postoperative Fatigue, Postoperative Sleep Disturbances
The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study
In the aftermath of major surgery, many patients suffer from pain, fatigue, reduced general well-being, and cognitive dysfunction.
- Conditions
- Postoperative Fatigue, Postoperative Sleep Disturbances, Surgical Stress Response
- Trial name
- DEXSLEEP (NCT06480539)
- Testing
- Dexmedetomidine
- Where
- Belgium
- Volunteers
- 102 people
- Sponsor
- Ziekenhuis Oost-Limburg
Obstructive Sleep Apnea, Neurocognitive Disorders
Postoperative Neurocognitive Disorders
The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery.
- Trial name
- PNCD (NCT04244162)
- Testing
- Brain Imaging, Cognitive testing, Blood Biomarkers
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea
Multimodal Postoperative Analgesia Following OSA Surgery
Assessment of the clinical efficacy and adverse effects of multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser) for postoperative analgesia…
- Trial name
- NCT04483427
- Testing
- Nalbuphine, ketorolac, accufuser
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Bahaa Mohammed Refaie
Stellate Ganglion Block
The Effect of Stellate Ganglion Block on Postoperative Sleep Disturbance and Cognitive Function in Elderly Surgical Patients
Postoperative delirium is an acute state of confusion, which is characterized by changes in attention and cognitive functions and fluctuations in consciousness; postoperative cognitive dysfunction is a common central nervous…
- Trial name
- NCT04800653
- Testing
- Stellate ganglion block
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Yangzhou University
Sleep Disturbance
Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery
This study aims to evaluate the effect of intraoperative dexamethasone on early postoperative sleep quality in adult patients undergoing nasal surgery under general anesthesia.
- Trial name
- NCT07550803
- Testing
- Dexamethasone, Normal Saline
- Volunteers
- 102 people
- Sponsor
- Seoul National University Hospital
Delirium
Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium
The investigators are performing this research study to understand the role of sleep disturbance on the incidence/severity of delirium after surgery.
- Trial name
- NCT03498560
- Testing
- PSG
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postoperative Pain, Postoperative Nausea
Outcomes of Carbohydrate Loading Paediatric Patients Preoperatively for Tonsillectomy and Adenoidectomy
Randomised control trial of 150 paediatric patients aged between 3-8years. One group will receive a preoperative carbohydrate oral drink and the other group will receive current standard care (no drink) prior to undergoing…
- Conditions
- Postoperative Pain, Postoperative Nausea, Satisfaction, Sleep
- Trial name
- NCT03639012
- Testing
- Carbohydrate drink
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jessica Gray
Recovery of Function, Postoperative Period
Early Heart Rate Variability and Sleep and Quality of Recovery After Cesarean Delivery
This prospective single-center observational cohort study investigates whether objectively measured early postoperative heart rate variability (HRV) and sleep parameters are associated with patient-reported quality of recovery…
- Conditions
- Recovery of Function, Postoperative Period, Cesarean Section
- Trial name
- Otonom-CS (NCT07897331)
- Testing
- Wearable-derived heart rate variability and sleep monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Buca Seyfi Demirsoy State Hospital
Obstructive Sleep Apnea, Sleep Disordered Breathing
Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea
In this study the investigators will determine whether using high flow oxygen in moderate-to-severe Obstructive Sleep Apnea patients following a major non cardiac surgery is more efficacious than usual care in preventing decrease…
- Trial name
- POSAII (NCT03964376)
- Testing
- Nasal High Flow, Usual Care
- Where
- 8 sites in Canada, Hong Kong and 2 more
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Breast Cancer, Postoperative Pain
Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery
Brief Summary: This prospective, single-center observational study examined the association between preoperative sleep quality and postoperative outcomes in women undergoing elective breast cancer surgery.
- Conditions
- Breast Cancer, Postoperative Pain, Inflammation
- Trial name
- NCT07547774
- Testing
- Preoperative Sleep Quality Assessment (PSQI)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Pain, Agitation, Emergence
Management of PADIS in Emergency Intensive Care Unit
Investigate the prevalence of PADIS in EICU, as well as the awareness and clinical implementation status of medical staff towards PADIS.
- Conditions
- Pain, Agitation, Emergence, Delirium, Critical Illness
- Trial name
- NCT06339385
- Testing
- PADIS assessment
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Capital Medical University
Delirium, Postoperative, Cognitive Decline
Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium
The goal of this prospective cohort study is to assess potential differences in sleep biomarkers in older adult patients undergoing major orthopedic surgery. The main questions it aims to answer are: 1.
- Conditions
- Delirium, Postoperative, Cognitive Decline, Dementia
- Trial name
- SLEEP-POD (NCT06052397)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Recurrent Tonsillitis, Obstructive Sleep Apnea
Post-operative Pain Control After Pediatric Adenotonsillectomy
Adenotonsillectomy is one of the most common surgical procedures performed in the pediatric population in the United States. It is generally a well-tolerated procedure with post-operative bleeding risk ranging from 3-5% in…
- Conditions
- Recurrent Tonsillitis, Obstructive Sleep Apnea, Sleep Disordered Breathing, Adverse Reaction to Drug
- Trial name
- NCT02296840
- Testing
- Ibuprofen, Hydrocodone-Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Postoperative Pain
The Effect of Esketamine on Postoperative Pain Relief in Patients Undergoing Laparoscopic Surgery
The purpose of this study is to investigate whether continuous intraoperative infusion of esketamine combined with the addition of esketamine to postoperative PCIA can improve postoperative pain and sleep quality in patients…
- Trial name
- NCT06300944
- Testing
- saline, Esketamine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- General Hospital of Ningxia Medical University
Postoperative Sleep Disturbance, Orthopedic Surgery Patients
Effect of ASMR and White Noise on Sleep Quality in Patients Undergoing Elective Lower Extremity Surgery
This randomized controlled trial aims to evaluate the effects of Autonomous Sensory Meridian Response (ASMR) and white noise on postoperative sleep quality in patients undergoing elective lower extremity surgery.
- Conditions
- Postoperative Sleep Disturbance, Orthopedic Surgery Patients, Sleep Quality
- Trial name
- SLEEP-ASMR (NCT07651228)
- Testing
- ASMR Audio Intervention, White Noise Audio Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- muzeyyen ataseven
Sleep, Atrial Fibrillation
Impact of Sleep Quality on Outcomes After Cardiac Surgery
Sleep is a basic human need and is essential for good quality of life, good health. In fact, humans spend one third of their life time in sleeping or attempting to do so.
- Conditions
- Sleep, Atrial Fibrillation, Delirium, Postoperative, Complications, Postoperative
- Trial name
- NCT06527105
- Testing
- Eye masks and ear plugs
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amrita Institute of Medical Sciences & Research Center
Preoperative Sleep Disorder, Preoperative Anxiety
Relationship Between Perioperative Related Factors and Inflammatory Markers and Postoperative Delirium in Elderly Patients With Non-cardiac Major Surgery
Perioperative neurocognitive impairment, including postoperative delirium (POD), is common in older patients after anesthesia and surgery and is associated with poorer short- and long-term outcomes, including worsening cognitive…
- Conditions
- Preoperative Sleep Disorder, Preoperative Anxiety, Inflammatory Reaction, Postoperative Delirium
- Trial name
- NCT05341531
- Testing
- elderly patients undergoing non-cardiac surgery
- Volunteers
- 400 people
- Sponsor
- Beijing Friendship Hospital
Tonsillitis, Obstructive Sleep Apnea
Study of Efficacy and Adverse Effects: Vessel Sealing System Tonsillectomy Versus Cold Knife Tonsillectomy
This study was planned to compare vessel sealing system tonsillectomy (VSST) to the traditional cold knife tonsillectomy (CKT) with special regard to intraoperative bleeding, operative time, postoperative pain and hemorrhage.
- Trial name
- NCT00636402
- Testing
- Cold Knife Tonsillectomy, Vessel Sealing System Tonsillectomy
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Chulalongkorn University
Rotator Cuff Tears
Effect of Gabapentin on Sleep and Opioid Use Following Rotator Cuff Repair
The goal of this clinical trial is to compare the effects of gabapentin in patients undergoing rotator cuff repair surgery. The main question it aims to answer is whether gabapentin can improve postoperative pain and sleep…
- Trial name
- NCT05800847
- Testing
- Gabapentin
- Volunteers
- 130 people
- Sponsor
- Hughston Clinic