Clinical trials: Postoperative Stress
Agitation, Pediatric Disorder
Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation.
Emergence agitation after sevoflurane anesthesia is still a problem needed to be solved.The aim of the study is to delineate the effect of caudal magnesium sulfate in children undergoing lower abdominal surgery to prevent…
- Trial name
- NCT02164773
- Testing
- Magnesium Sulfate, 0.9%normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Congenital Heart Disease
The Efficacy of Systematic Oral Feeding Education Program
After the intervention of Systematic Oral Feeding Education Program: 1. The feeding techniques scores of the main caregivers in the experimental group will be higher than those in the control group. 2.
- Trial name
- SOFEP (NCT06763497)
- Testing
- Systematic Oral Feeding Education Program
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Corneal Endothelial Cell Loss, Ozone Therapy
Effect of Systemic Ozone Therapy on Corneal Endothelium
This study evaluates the safety of systemic ozone therapy on the corneal endothelium, a vital non-renewable tissue that maintains corneal transparency.
- Trial name
- OZON-CORNEA (NCT07718100)
- Testing
- Systemic Ozone Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Colorectal Neoplasm, Liver Neoplasm
A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver
Patients with unresectable metastatic colorectal cancer confined to the liver will undergo a 1 hour hyperthermic isolated hepatic perfusion (IHP) with escalating dose melphalan.
- Conditions
- Colorectal Neoplasm, Liver Neoplasm, Neoplasm Metastasis
- Trial name
- NCT00001576
- Testing
- Melphalan, Floxuridine, Leucovorin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Cancer Institute (NCI)
Colorectal Cancer
Cytokine Changes After Colorectal Cancer Resection
Based on our previous research, this study aims to determine reliable surgical stress response markers in patients undergoing radical resection of colorectal cancer.
- Trial name
- NCT01244022
- Testing
- colorectal cancer resection
- Where
- Croatia
- Volunteers
- 28 people
- Sponsor
- University Hospital Dubrava
Postoperative Complications, Liver Diseases
Physical Recovery After Laparoscopic vs. Open Liver Resection
The role of laparoscopic liver surgery with respect to clinical outcome remains unclear.
- Conditions
- Postoperative Complications, Liver Diseases, Physical Stress, Surgery
- Trial name
- NCT04067349
- Testing
- Ergometry
- Where
- Austria
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Anesthesia, General, Airway Management
Effect of Laryngeal Mask Cuff Shape on Pharyngeal Stress
Laryngeal masks are widely used supraglottic airway devices, but their cuffs differ considerably in shape and design. The cuff exerts pressure on the pharyngeal structures, which may provoke a physiological stress response and…
- Conditions
- Anesthesia, General, Airway Management, Postoperative Sore Throat
- Trial name
- CUFFSTRESS (NCT07868848)
- Testing
- SaCoVLM video laryngeal mask, LMA Supreme, Ambu AuraGain
- Where
- 2 sites in Czechia
- Volunteers
- 162 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Heart Surgery
Effect of Oral Zinc and Vitamin E Supplementation on Short-term Postoperative Outcomes in Cardiac Surgery Patients.
Cardiac surgery can cause oxidative stress due to ischemia-reperfusion. Using antioxidants during perioperative period may help improve this condition. Vitamin E and zinc have antioxidant effects.
- Trial name
- NCT05402826
- Testing
- Oral zinc + vitamin E
- Where
- Iran
- Volunteers
- 78 people
- Sponsor
- Shahid Beheshti University
Post-traumatic Stress Symptoms, Anxiety
Psychological Prehabilitation for Complex Gastrointestinal Surgery
The goal of this clinical trial is to learn if a psychological program before surgery can help adults who have lasting stress from past medical experiences. The program is called PREPARE-GI.
- Conditions
- Post-traumatic Stress Symptoms, Anxiety, Depression Disorder, Gastrointestinal Disease
- Trial name
- PREPARE-GI (NCT07865052)
- Testing
- PREPARE-GI
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Post-operative Voiding
Assessment of Voiding After Sling
The purpose of this study is to compare the incidence of catheterization from discharge to 6 weeks postoperatively when using two methods of post-operative voiding evaluation after a mid-urethral sling procedure.
- Trial name
- AVAS (NCT01343784)
- Testing
- Urinary voiding assessment after midurethral sling
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- The Cleveland Clinic
Stress Urinary Incontinence, Urinary Retention Postoperative
Incidence of Short-term Urinary Retention After Fascial Retropubic Sling: Prospective and Randomized Analysis.
The aim of this study is to evaluate the incidence of short-term urinary retention and the cure rate in patients with stress urinary incontinence undergoing surgical treatment with fascial pubovaginal sling with two tension…
- Conditions
- Stress Urinary Incontinence, Urinary Retention Postoperative, Urinary Retention After Procedure
- Trial name
- NCT04465578
- Testing
- Sling tension adjustment by classic technique, Sling tension adjustment by height of 4 cm
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cardiac Arrest
Reoxygenation After Cardiac Arrest II (REOX II Study)
The broad objective of this study is to test the association between hyperoxia exposure after resuscitation from cardiac arrest and outcome.
- Trial name
- REOX II (NCT02698826)
- Testing
- Protocol for rapid FiO2 optimization
- Where
- 5 sites in United States
- Volunteers
- 16 people
- Sponsor
- The Cooper Health System
Uterine Fibroids (UF)
Ultrasound-Guided Stellate Ganglion Block Plus Propofol for Perimenopausal Insomnia With Anxiety
Laparoscopic myomectomy is a commonly performed minimally invasive gynecologic procedure. However, surgical trauma, tracheal intubation, and pneumoperitoneum may induce pronounced perioperative stress responses, resulting in…
- Trial name
- SGB-PROP-PIA (NCT07384468)
- Testing
- Ultrasound-Guided Stellate Ganglion Block
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Xiaochen Ji
Pain Management
The Effect of Mindfulness-Based Stress Reduction Training Before Mastectomy on Postoperative Pain in Early Period
This research aims to investigate the effect of mindfulness-based stress reduction training given before mastectomy on postoperative early period pain and the fear of movement caused by pain.
- Trial name
- NCT06349395
- Testing
- MBSR surgical nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Infertility, Anesthesia
The Effect of Music Therapy on Glutathione Peroxidase, Malondialdehyde and Pain in Oocyt Pick Up Patients.
It is used by music therapists to help the social, physical, emotional, psychological and psychological needs of patients. In a study, music has a positive effect on pain, anxiety, depression, shortness of breath, mood, facial…
- Conditions
- Infertility, Anesthesia, Oxidative Stress, Pain, Postoperative
- Trial name
- NCT04175873
- Testing
- music
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Oophorectomy, Oxidative Stress
Role of Oxidative Stress in Ovarian Tissue After CO2-pneumoperitoneum Application-induced I/R
Because of cellular changes in response to ischemia and a following period of reperfusion, damages to organs and different tissues occur.
- Conditions
- Oophorectomy, Oxidative Stress, Ischemia Reperfusion Injury
- Trial name
- NCT04493983
- Testing
- laparoscopic salpingo-oophorectomy, Laparoscopic bilateral salpingo-oophorectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ismet Hortu
Post-operative Breast Cancer
The Effect of Inspiratory Muscle Training on Breast Cancer Patients Undergoing Surgery
This study will address the female patients who are exposed to surgery after breast cancer. strength training for the inspiratory muscles will be applied in addition to the traditional care including physical therapy that will be…
- Trial name
- NCT06091696
- Testing
- inspiratory muscle training, Aerobic exercises
- Where
- Saudi Arabia
- Volunteers
- 47 people
- Sponsor
- University of Hail
Ischemic Heart Disease
Exploration of Cerebral Pathophysiology During and After CABG Using CPB
Purpose: The purpose of this study is to examine cerebral oxidative and inflammatory stress and cerebral hemodynamics during and after coronary artery bypass grafting and correlate with postoperative cognitive function.
- Trial name
- NCT02941380
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Preoperative Anxiety, Postoperative Pain
Recovery With Virtual Reality for Stress and Pain
This randomized controlled trial will evaluate whether a brief preoperative virtual reality intervention reduces anxiety and improves early recovery in adults undergoing elective gynecological surgery.
- Conditions
- Preoperative Anxiety, Postoperative Pain, Postoperative Recovery
- Trial name
- ReVRS (NCT07679022)
- Testing
- Preoperative Virtual Reality, Usual Perioperative Care
- Volunteers
- 140 people
- Sponsor
- Region Skane
Postoperative Fatigue, Postoperative Sleep Disturbances
The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study
In the aftermath of major surgery, many patients suffer from pain, fatigue, reduced general well-being, and cognitive dysfunction.
- Conditions
- Postoperative Fatigue, Postoperative Sleep Disturbances, Surgical Stress Response
- Trial name
- DEXSLEEP (NCT06480539)
- Testing
- Dexmedetomidine
- Where
- Belgium
- Volunteers
- 102 people
- Sponsor
- Ziekenhuis Oost-Limburg