Clinical trials: Postpartum Depression (PPD)
Postpartum Depression
1-Day CBT Workshops for PPD
Postpartum depression (PPD) affects up to 20% of women and has profound effects on women and their families. Clinical practice guidelines recommend that the majority of women with PPD receive psychotherapy.
- Trial name
- NCT03654261
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 461 people
- Sponsor
- McMaster University
Postpartum Depression (PPD), Postpartum Anxiety
Online Transdiagnostic Group CBT for Postpartum Depression and Anxiety
The purpose of this pilot study is to test the feasibility of an online 10-Week group cognitive behavioural therapy (CBT; a type of talking therapy) intervention for postpartum depression and anxiety that is led by…
- Trial name
- NCT07162129
- Testing
- Cognitive Behavioral Therapy for Postpartum Depression (PPD) and Anxiety
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McMaster University
Postpartum Depression (PPD)
Positive Psychology-Based Intervention Program for Postpartum Depression Within Primary Healthcare System
This study is a prospective, two-arm parallel cluster randomized controlled trial that will compare the intervention effects of a positive psychology-based intervention package with usual care for postpartum depression.
- Trial name
- NCT06770244
- Testing
- positive psychology-based intervention package
- Where
- China
- Volunteers
- 1,438 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Postpartum Depression
Public Health Nurse-Peer Co-Led Group Cognitive Behavioral Therapy for Postpartum Depression
The purpose of this study is to determine the effectiveness of an online 9-week group Cognitive Behavioural Therapy (CBT; a type of talking therapy) intervention that is co-led by public health nurses (PHNs) and individuals who…
- Trial name
- NCT06597448
- Testing
- Cognitive Behavioral Therapy for Postpartum Depression (PPD)
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McMaster University
Postpartum Depression
Online 1-Day CBT-Based Workshops for PPD
Postpartum depression (PPD) already affects up to 1 in 5 women and left untreated costs $150,000 per case over the lifespan. Under normal conditions, just 10% of women with PPD get evidence-based treatment, a situation that has…
- Trial name
- NCT04485000
- Testing
- Online 1-Day Cognitive Behavioural Therapy (CBT)-Based Workshop
- Where
- Canada
- Volunteers
- 403 people
- Sponsor
- McMaster University
Postpartum Depression
Peer Administered Online CBT for PPD
Postpartum depression (PPD) affects up to one in five of women and has profound effects on mothers and their infants. Unfortunately, fewer than 15% of women with PPD receive evidence-based care.
- Trial name
- PL-OCBT (NCT04913584)
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- McMaster University
Postpartum Depression, Depression
Screening Evaluation for Women With Postpartum Depression
This study evaluates the relationship between mood changes and hormones in women with postpartum depression (PPD). This is an observational study; volunteers who participate will not receive any new or experimental therapies.
- Trial name
- NCT00056901
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Postnatal Depression, Postpartum Depression (PPD)
Qualitative Study on the Experiences of Mothers 6 to 12 Months After Their Participation in the Mother-baby Groups of the HUGS Study
The HUGS-QUALI study is a qualitative investigation that explores the experiences of mothers who participated in HUGS mother-baby therapy groups.
- Trial name
- HUGSquali (NCT07017621)
- Where
- 4 sites in France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Toulouse
Depression, Postpartum
A Study to Learn More About How Zuranolone Affects Postpartum Depression Symptoms in Participants Who Took it Within 1 Year After The End of Their Pregnancy
In this study, researchers will learn more about how zuranolone affects the symptoms of postpartum depression, also known as PPD. Zuranolone is a drug that healthcare professionals can prescribe for adults with PPD.
- Trial name
- NCT07047820
- Testing
- Zuranolone
- Where
- United States
- Volunteers
- 305 people
- Sponsor
- Biogen
Postpartum Depression (PPD)
Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression
The proposed study is an open-label trial of Re-Timer® wearable morning bright light therapy for postpartum depression. The study is focused on evaluating the feasibility, acceptability, and implementation context of morning…
- Trial name
- NCT07766161
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Postpartum Depression
[Study Evaluating the Efficacy and Safety of a Digital Therapeutic as an Adjunct to TAU in Postpartum Depression]
This study evaluates the efficacy of two digital therapeutics, WB001 and ED001, on depressive symptoms among women diagnosed with postpartum depression.
- Trial name
- NCT05551195
- Testing
- WB001, ED001
- Where
- 8 sites in United States
- Volunteers
- 7 people
- Sponsor
- Woebot Health
Postpartum Depression (PPD)
Intranasal Dexmedetomidine for Postpartum Depression Prevention
Brief Title: Intranasal Dexmedetomidine for Postpartum Depression Prevention: A Randomized Trial This study aims to evaluate the effect of intranasal dexmedetomidine (Dex) administered before combined spinal-epidural labor…
- Trial name
- NCT07501728
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Postpartum Depression
Public Health Nurse-Delivered 1-Day CBT Workshops for PPD
Public Health Nurses (PHN) received training to deliver a day-long Cognitive Behavioural Therapy (CBT)-based workshop for treating postpartum depression (PPD).
- Trial name
- NCT05622305
- Testing
- 1-Day Cognitive Behavioural Therapy-Based Workshop
- Where
- Canada
- Volunteers
- 451 people
- Sponsor
- McMaster University
Depression, Postpartum
CHS Nurses Clinical Competence in Detecting Signs of PPD in Non-Native Speaking Immigrant Mothers'
The aim is to develop, test and evaluate an educational intervention with the purpose to strengthen Child Health Services (CHS) Nurses clinical competence in detecting signs of postpartum depression in non-native-speaking…
- Trial name
- NCT04167709
- Testing
- Education in clinical competence in detecting signs of postpartum depression in immigrant mothers
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Lund University
Postpartum Depression
Early Diagnosis of PPD Through Self-portraits
the target of the research is development of a predictive tool for early identification of women which are at higher risk for development of postpartum depression.
- Trial name
- ppd (NCT03791021)
- Testing
- draw a person (DAP), Edinburgh Postnatal Depression Scale (EPDS), Beck Depression Inventory- II (BDI-II)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Postpartum Depression (PPD), Postpartum Anxiety
Investigation of TVNS Administration on Postpartum Mental Health
The aim of the study is to explore whether transcutaneous vagus nerve stimulation (tVNS) may be effective in preventing mood swings and depressive symptoms in the postpartum phase, as well as serving as a supplementary…
- Conditions
- Postpartum Depression (PPD), Postpartum Anxiety, Postpartum Sadness, Postpartum Blues
- Trial name
- NCT06682689
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Postpartum Depression
Online PHN CBT for PPD
The primary objective of this study is to determine if online group CBT for PPD delivered by public health nurses is superior to postnatal care as usual in: a) acutely treating PPD, b) reducing relapse and recurrence, c)…
- Trial name
- NCT04928742
- Testing
- Group Cognitive Behavioural Therapy (CBT)
- Where
- Canada
- Volunteers
- 159 people
- Sponsor
- McMaster University
Severe Postpartum Depression
A Study of BRII-296 in Adults With Severe Postpartum Depression (PPD)
The primary purpose of this study is to evaluate the safety and tolerability of BRII-296 administered by 2 intramuscular injections, administered with Depo Medrol as assessed by the incidence of adverse events, changes from…
- Trial name
- NCT06057012
- Testing
- BRII-296, Depo Medrol
- Where
- 11 sites in United States
- Volunteers
- 11 people
- Sponsor
- Brii Biosciences Limited
PostPartum Depression
Curio Digital Therapy for the Treatment of Post-partum Depression
Primary Objective: Evaluate the clinical effectiveness of the MamaLift Plus app compared to control (digital sham plus treatment as usual) for the management of PPD in the observed population for a period of 9 calendar weeks.
- Trial name
- SuMMER (NCT05958095)
- Testing
- MamaLift Plus
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Healthcare Innovation Technology Lab
Virtual Reality, Postpartum Depression (PPD)
Virtual Reality-Assisted Intraoperative Sensory Modulation on Postpartum Depression and the Kynurenine Pathway
The research will be conducted as a prospective, observational, and comparative study with 98 pregnant volunteers aged 18-45 at Düzce University Faculty of Medicine.
- Conditions
- Virtual Reality, Postpartum Depression (PPD), Kynurenine Pathway and Its Metabolites, Pregnancy
- Trial name
- VR effect (NCT07300176)
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Duzce University