Clinical trials: Postpartum Depressive Symptoms
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Postpartum Depression
Translating Research Into Practice for Postpartum Depression
This is a study to assess the impact of introducing screening and planned follow up for postpartum depression. All women ages 18 to 45 who speak English or Spanish who come to the enrolled community family medicine offices will…
- Trial name
- TRIPPD (NCT00548743)
- Testing
- Screening and follow up, Usual care
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Olmsted Medical Center
Depression, Postpartum
The Impact of Creative Interventions on Symptoms of Postnatal Depression (Cohort Study)
Post-natal depression (PND) is anticipated to affect 12.9% of new mothers with at least 75,000 cases per year in the UK alone. However, despite this, there is currently a worrying lack of support for new mothers, with data…
- Trial name
- NCT02526433
- Where
- United Kingdom
- Volunteers
- 2,558 people, healthy volunteers welcome
- Sponsor
- Royal College of Music
Pain, Postoperative, Depression, Postpartum
Ketamine Tolerated Dose for Postpartum Depression and Pain After Cesarean Delivery (PREPARE 1)
The purpose of this study is to identify a tolerable dose for postpartum ketamine infusion using a maximum tolerated dose (MTD) 3+3 design.
- Trial name
- NCT05907213
- Testing
- Ketamine (Ketalar) Dose Level 1, Ketamine (Ketalar) Dose Level 2, Ketamine (Ketalar) Dose Level 3
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Substance Abuse, Post-partum Depression
Cradling Our Future Through Family Strengthening Study
The purpose of this study is to determine whether an in-home, paraprofessional-delivered family strengthening curriculum entitled Family Spirit is effective at increasing parental competence, improving maternal outcomes and…
- Conditions
- Substance Abuse, Post-partum Depression, Depression
- Trial name
- NCT00373750
- Testing
- Family Spirit Intervention
- Where
- 5 sites in United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pregnancy, Depression
The Staying Well Study: An Open Trial of Mindfulness-Based Cognitive Therapy for the Prevention of Perinatal Depression
Pregnant women with histories of depression are at high risk of depressive relapse during the perinatal period, and options for relapse prevention are limited.
- Conditions
- Pregnancy, Depression, Postpartum Depression
- Trial name
- NCT02391870
- Testing
- MBCT-PD
- Where
- 4 sites in United States
- Volunteers
- 49 people
- Sponsor
- University of Colorado, Boulder
Depression During Pregnancy, Depression, Postpartum
IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression
The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations.
- Trial name
- NCT06746337
- Testing
- IMAGINE
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Postpartum Depression, Infant Development
Social Circumstances, Parenting Techniques, and Infant Development
1. Investigators aim to assess a novel behavioral intervention (currently approved in Protocol #6285) behavioral intervention that promotes maternally-mediated behavioral changes in young infants to reduce the risk of postpartum…
- Conditions
- Postpartum Depression, Infant Development, Rhythm; Sleep
- Trial name
- NCT02121496
- Testing
- Resources for Postpartum Parenting
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Depression
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers
This study will aim to prevent postpartum depression in pregnant teenagers through an interpersonal therapy-based program.
- Trial name
- NCT00436150
- Testing
- Interpersonal therapy-based treatment, Standard care
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Postpartum Depression (PPD)
Evaluating the Effectiveness of an Internet-based Therapy (iCARE) to Treat Symptoms of Postpartum Depression
Postpartum depression (PPD) is a common and serious condition affecting 9.5% of women in high-income countries, and around 8% in Denmark.
- Trial name
- iCARE (NCT07384273)
- Testing
- Internet-based therapy (iCARE) and treatment as usual, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 352 people
- Sponsor
- University of Southern Denmark