Clinical trials: Postpartum Gestational Diabetes Mellitus
Dietary Modification, Weight Loss
Feasibility of a Postpartum Lifestyle Intervention on the Cardiometabolic Risk Profile of GDM Women
The goal of the study is to investigate the effect of a lifestyle intervention program (adoption of exclusive breastfeeding, healthy diet and regular physical activity) on minimizing postpartum weight retention among women with…
- Conditions
- Dietary Modification, Weight Loss, Physical Activity, Breastfeeding
- Trial name
- DEPART (NCT02872402)
- Testing
- Lifestyle intervention, Active control lifestyle intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
Gestational Diabetes, Type 2 Diabetes Mellitus
Face-it: Health Promotion for Women With Prior Gestational Diabetes
This project focuses on evaluating a health promotion intervention among families where the mother has prior gestational diabetes mellitus (GDM) in the first year after delivery.
- Conditions
- Gestational Diabetes, Type 2 Diabetes Mellitus, Quality of Life
- Trial name
- Face-it (NCT03997773)
- Testing
- Face-it Intervention
- Where
- 3 sites in Denmark
- Volunteers
- 277 people
- Sponsor
- Steno Diabetes Center Copenhagen
Gestational Diabetes, PreDiabetes
mHealth Smartphone App and Postpartum Glucose Intolerance for Patients With GDM
Without intervention, approximately 70% of women diagnosed with GDM will develop type 2 diabetes mellitus in their lifetime. Abnormal results of a 2 hour oral glucose tolerance test (OGTT) performed as early as 2 days postpartum…
- Conditions
- Gestational Diabetes, PreDiabetes, Pregnancy Related, Pregnancy, High Risk
- Trial name
- NCT05597943
- Testing
- Malama App
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Diabetes, Gestational, PreDiabetes
A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes
This study is testing whether daily metformin for 1 year postpartum can reduce risk of diabetes in patients who had gestational diabetes.
- Conditions
- Diabetes, Gestational, PreDiabetes, Diabetes Mellitus, Type 2
- Trial name
- NCT05280496
- Testing
- Metformin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Tufts Medical Center
Gestational Diabetes
Effect of Extra Virgin Olive Oil Addition in the Diet of Women With Gestational Diabetes Mellitus (OLIDIAG)
Gestational diabetes mellitus (GDM) is associated to adverse maternal and neonatal outcomes. The aim of this study is to address whether the addition of extra virgin olive oil to the diet of women with GDM improves maternal…
- Trial name
- OLIDIAG (NCT05120388)
- Testing
- Extra Virgin Olive Oil Addition
- Where
- Argentina
- Volunteers
- 190 people
- Sponsor
- Center for Pharmacological and Botanical Research
Diabetes, Gestational
Text-message Reminders to Increase Rates of Postpartum Diabetes Screening in Women With Gestational Diabetes
Purpose: The purpose of this study is to see whether a text-message reminder system will increase the number of women who complete their diabetes screening after delivery.
- Trial name
- NCT02013557
- Testing
- Text-message reminder
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of South Florida
Glucose Intolerance After a Recent History of Gestational Diabetes
Semaglutide for the Treatment of Glucose Intolerance in Women With Prior Gestational Diabetes
Gestational diabetes (GDM) is an important contributor to the increasing prevalence of type 2 diabetes (T2DM). Women with glucose intolerance in early postpartum are a particularly high-risk group with about 50% who will develop…
- Trial name
- SERENA (NCT05569772)
- Testing
- Semaglutide Pen Injector
- Where
- 13 sites in Belgium
- Volunteers
- 252 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gestational Diabetes, Breast Feeding
Exclusive Breastfeeding Improves Puerperal Glucose Metabolism in Pregnant Women With Gestational Diabetes Mellitus and Links to Lipids Composition
Breastfeeding could effectively be associated with a lower risk of future type 2 diabetes (T2D) in women with gestational diabetes mellitus (GDM), but the short-term protective impact of puerperal breastfeeding on maternal…
- Conditions
- Gestational Diabetes, Breast Feeding, Lipid Metabolism Disorders
- Trial name
- NCT05629403
- Testing
- observe
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Nanjing Medical University
Gestational Diabetes, Vascular Endothelial Function
Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes
The purpose of this investigation is to examine the role of oxidative stress in aberrant microvascular function in otherwise healthy women with a history of GDM.
- Trial name
- NCT05946785
- Testing
- Acetylcholine, insulin aspart
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD
Gestational Diabetes Mellitus
The Impact of Vitamin D Supplementation on Glucose Metabolism in Chinese Women With Former Gestational Diabetes Mellitus
Vitamin D deficiency are related to insulin resistance and impaired beta-cell function.It is reported that the level of vitamin D is lower during pregnancy and postpartum in the women with Gestational Diabetes Mellitus.
- Trial name
- NCT03138616
- Testing
- vitamin D
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Gestational Diabetes
Postpartum Glycemia in Women At Risk for Persistent Hyperglycemia
GDM is characterized by decreased insulin sensitivity, decreased insulin secretion, or a combination of both. Women with GDM are at significant risk for overt T2DM later in life, and postpartum insulin sensitivity and secretion…
- Trial name
- NCT04521712
- Testing
- 2-hour 75-g oral glucose tolerance test and Dexcom G6 Pro continuous glucose monitor
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Gestational Diabetes, Preventive Care / Anticipatory Guidance
SWEET: Postpartum Navigation After GDM
This study is a pilot assessment of Sustaining Women's Engagement and Enabling Transitions after GDM (SWEET), a GDM-focused intervention that will apply barrier-reduction patient navigation strategies to improve health after a…
- Conditions
- Gestational Diabetes, Preventive Care / Anticipatory Guidance, Retention in Care, Postpartum Health
- Trial name
- SWEET (NCT04583839)
- Testing
- Patient Navigation Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Gestational Diabetes, Glucose Metabolism Disorders
Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)
This study aims to test the following hypotheses in a randomized controlled trial of post-partum women with a history of gestational diabetes mellitus (GDM) that will be followed up for up to 4 years: 1.
- Conditions
- Gestational Diabetes, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- I-HIPS (NCT05081037)
- Testing
- Wearable Care Group
- Where
- Singapore
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes
Is Fat in the Liver a Marker of Post-Pregnancy Glycaemic Deterioration in Women With Gestational Diabetes?
The aim of this study is to utilise ultrasound, using an established method for detecting NAFLD, to determine whether the presence of NAFLD in women with GDM, detected during routine scanning, is a marker of deterioration in…
- Trial name
- FLiP-GD2 (NCT04362540)
- Testing
- MRI scan
- Where
- United Kingdom
- Volunteers
- 189 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Diabetes, Gestational
Insulin Sensitivity and Secretion During Pregnancy and Post Partum in Women With Gestational Diabetes.
Aim of the study: To define insulin requirement during pregnancy and to identify the rapid changes in insulin sensitivity around parturition and the first 6 months post partum.
- Trial name
- NCT02770079
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Gestational Diabetes
Postpartum Continuous Glucose Monitoring (CGM) Study
This research study is being done to assess if using a glucose sensor (also known as a continuous glucose monitor) after childbirth can help identify women who are at risk of developing diabetes after having diabetes during…
- Trial name
- NCT05714761
- Testing
- Dexcom glucose sensor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gestational Diabetes, Glucose Intolerance
Postpartum Weight Loss and Exercise (PRIDE)
The overall objective of this pilot project is to test in 50 women with a history of gestational diabetes mellitus (GDM), the effectiveness and feasibility of an 8 month intensive lifestyle intervention to reduce the rate of…
- Trial name
- PRIDE (NCT01296516)
- Testing
- Non-intervention group, Face to face, Telehelath Group
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Pennington Biomedical Research Center
Gestational Diabetes
Immediate Postpartum Glucose Tolerance Testing
The objective of this study is to compare the accuracy of a 2hr glucose tolerance test administered during the postpartum hospitalization with the standard of care glucose tolerance testing (administered at 6 weeks postpartum).
- Trial name
- NCT04199676
- Testing
- Glucose tolerance test
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Diabetes Mellitus, Type 2
Comprehensive Postpartum Screening Strategies for Women With Gestational Diabetes Mellitus (GDM)
Previous gestational diabetes (GDM) predisposes affected women to diabetes. Pregnancy, in essence, serves as a metabolic stress test and uncovers underlying insulin resistance and ß-cell dysfunction.
- Trial name
- COPSS-GDM (NCT00849849)
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Woman's
Gestational Diabetes Mellitus, Pregnancy
GooDMoMS: A Multimodel Pregnancy and Postpartum Intervention for Gestational Diabetics
This study includes a behavioral educational intervention that focuses on healthy eating and physical activity during pregnancy and the postpartum among women newly diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- NCT01600534
- Testing
- lifestyle counseling
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill