Clinical trials: Postpartum Haemorrhage
Postpartum Hemorrhage
Tranexamic Acid for the Prevention of Postpartum Haemorrhage
Use of tranexamic acid (TXA) for the prevention of postpartum haemorrhage (PPH) after cesarean section in high-risk patients ( a randomized control trial ).
- Trial name
- NCT04707950
- Testing
- Tranexamic Acid 100 milligram/Milliliter, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Placenta Accreta
Internal Iliac Artery Occlusion in Placenta Accreta
This is a randomized study to assess the efficacy of prophylactic bilateral internal iliac artery occlusion performed prior to planned surgical management for placenta accreta spectrum (PAS).
- Trial name
- NCT04423263
- Testing
- Bilateral internal iliac artery balloon occlusion, Control
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Voon Hian Yan
Postpartum Hemorrhage
Coagulation Factors and Postpartum Hemorrhage
Objective is to analyze a possible association of coagulation factors peripartal with the occurrence of postpartum hemorrhage.
- Trial name
- NCT02604602
- Testing
- blood exam
- Where
- Switzerland
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Postpartum Hemorrhage
Feasibility Trial of the Circumferential Abdominal Pelvic Pressure Device (CAPP)
A group of midwives and obstetric nurses have been trained to use circumferential abdominal pelvic pressure (CAPP) to treat postpartum hemorrhage.
- Trial name
- NCT01497756
- Testing
- CAPP use
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of New Mexico
Postpartum Hemorrhage
Uterine Massage After Vaginal Delivery
The participants will be randomized into an oxytocin plus uterine massage group and an oxytocin-only group in the third stage of the labor.
- Trial name
- NCT03858569
- Testing
- active management of third stage of labor
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Postpartum Haemorrhage
Towards Better Prognostic and Diagnostic Strategies for Haemostatic Changes During Major Obstetric Haemorrhage
Major obstetric haemorrhage (MOH) remains a cause of significant maternal morbidity and mortality worldwide. By identifying women with a higher a priori risk of major haemorrhage during their pregnancy or early during postpartum…
- Trial name
- TeMpOH-2 (NCT02149472)
- Where
- Netherlands
- Volunteers
- 1,649 people, healthy volunteers welcome
- Sponsor
- Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research
Postpartum Hemorrhage
Postpartum Hemorrhage and Alterations in Uterine Ecostructure
The goal of this observational study is to evaluate the presence of alterations in the ecostructure of the uterus in patients with a positive history of primary postpartum hemorrhage, in order to demonstrate a statistically…
- Trial name
- NCT06781528
- Testing
- Ultrasound evaluation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Blood Loss, Surgical
B-lynch Transverse Compression Suture
Is B-Lynch transverse compression suture safe and effective in controlling excessive blood loss during conservative management of women with placenta previa?
- Trial name
- NCT06359886
- Testing
- B-Lynch Transverse Compression Suture
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Alexandria University
Postpartum Hemorrhage
Amr's Maneuver and Postpartum Hemorrhage
The impacts of using Amr's manoeuvre (cervical traction) on atonic postpartum hemorrhage is a randomized controlled, multi-centre study that aims to compare the incidence of post partum hemorrhage (PPH> 500 ml blood loss) within…
- Trial name
- NCT02660567
- Testing
- Amr maneuver
- Where
- Egypt
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- ClinAmygate
Postpartum Hemorrhage
Comparison Between Rectal & Sublingual Misoprostol Before Caesarian Section To Reduce Intra & Post-Operative Blood Loss
The aim of the work is to evaluate \& compare the effectiveness of rectally administered PGE1 synthetic analogue (misoprostol) 400 microgram versus sublingually administered misoprostol before caesarean section to decrease blood…
- Trial name
- NCT02083107
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postpartum Hemorrhage \(PPH\)
Comparison of the Effect of Carbetocin Versus Oxytocin in the Prevention of Postpartum Hemorrhage After Emergency Caesarean Section in Antenatal Low-risk Patients
This study will be conducted to compare the effects of pabal and oxytocin administered to prevent postpartum hemorrhage in patients who were followed in the delivery room due to vaginal labor but underwent cesarean section due to…
- Trial name
- EMERGE-CS (NCT07380529)
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Postpartum Hemorrhage
Misoprostol and Oxytocin in Uniject® for Postpartum Hemorrhage Prevention in Communities
This community-based cluster Randomised Control Trial will assess the feasibility, cost, risks and benefits of use of oral Misoprostol and parenteral Oxytocin in Uniject® as prophylaxis for postpartum hemorrhage (PPH) in…
- Trial name
- NCT01710566
- Testing
- Misoprostol, Oxytocin
- Sponsor
- Gynuity Health Projects
Nurse Education, Nursing Students
The Effectiveness of Serious Game-Based Training for Nursing Students in Postpartum Haemorrhage Management
This randomized controlled trial evaluated the incremental effect of adding a web-based serious game to standard theoretical instruction on third-year nursing students' postpartum hemorrhage management knowledge, task-specific…
- Conditions
- Nurse Education, Nursing Students, Postpartum Hemorrhage, Nursing Care
- Trial name
- NCT07229573
- Testing
- Web-Based Serious Game
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Umbilical Cord
Timing of Umbilical Cord Clamping: One to Three Minutes vs. After Cessation of Cord Pulsation
The timing of umbilical cord clamping has been widely discussed in the scientific community. As part of the worldwide strategies to reduce childhood iron deficiency anemia, the incorporation of late clamping (at least one minute…
- Trial name
- CORD (NCT03844490)
- Testing
- CESSATION OF CORD PULSE, CONTROL
- Where
- Brazil
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Postpartum Hemorrhage
Spontaneous and Oxytocin-induced Contractility After Exposure to Intravenous Anesthetic Agents: an In-vitro Study in Human Myometrium
Poor uterine tone after the birth of a baby may cause serious bleeding (called postpartum hemorrhage or PPH). This is a major cause of maternal death worldwide. In the developed world the cesarean section rate is increasing.
- Trial name
- NCT03852797
- Testing
- Oxytocin, Ketamine, Propofol
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postpartum Hemorrhage
The Association Between Shock Index and Severity of Postpartum Blood Loss
The present study aims to determine the relationship between postpartum changes in the shock index and the severity of blood loss and other PPH results.
- Trial name
- NCT03135158
- Testing
- Exposure to vaginal delivery
- Where
- Colombia
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Placenta Previa With Hemorrhage - Delivered, Placenta Accreta
A.Chohan Continuous Squeezing Suture (ACCSS) for Placenta Previa / Accreta
Placenta praevia and accreta spectrum disorders are rising in incidence due to increased rate of repeat caesarean sections. Peripartum hysterectomy remains the only definitive treatment of massive postpartum haemorrhage related…
- Trial name
- ACCSS (NCT04660578)
- Testing
- ACCSS
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- King Edward Medical University
Postpartum Hemorrhage
The PPHgb Study: Non-Invasive Hemoglobin Measurement
This project is a prospective observational study aimed to assess the use of non-invasive hemoglobin measurement in anticipating postpartum hemorrhage and predicting estimated blood loss.
- Trial name
- NCT05046964
- Testing
- Masimo Radical-7 Pulse CO-Oximeter
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- George Washington University
Postpartum Hemorrhage
Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women At Higher Risk
Heavy bleeding after childbirth, known as a postpartum haemorrhage (PPH), causes about 70,000 maternal deaths every year. Tranexamic acid (TXA) is a lifesaving treatment for women with PPH.
- Trial name
- I'M-WOMAN (NCT05562609)
- Testing
- Tranexamic acid
- Where
- Tanzania
- Volunteers
- 30,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine