Clinical trials: Postpartum Haemorrhage (PPH)
PPH - Postpartum Hemorrhage, Eclampsia
Comparing Simulated Patients and Manikin Based Simulation in Obstetrics
The aim of this randomized study is to compare a live, trained simulated patient with a high-fidelity manikin in obstetric emergency team training using two standardized scenarios.
- Trial name
- NCT07857551
- Testing
- Trained, standardized patient, MamaAnne Patient Simulator
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Postpartum Hemorrhage, Carbetocin
Timing of Carbetocin Administration in Postpartum Hemorrhage
Postpartum haemorrhage (PPH) is one of the major contributors to maternal mortality and morbidity worldwide. Active management of the third stage of labour has been proven to be effective in the prevention of PPH.
- Trial name
- NCT06776926
- Testing
- Carbetocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mehmet Mete Kırlangıç
Postpartum Hemorrhage
Misoprostol for Treatment of Postpartum Hemorrhage at Community-level Births in Egypt
This randomized controlled community-based trial will assess the effectiveness of administration of 800 mcg sublingual misoprostol with standard of care vs.
- Trial name
- NCT01619072
- Testing
- Misoprostol + referral
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Post Partum Haemorrhage
Clinical Study to Assess the Equivalence of Tranexamic Acid vs Oxytocin in Reducing the PPH
The purpose of this study was to evaluate that the tranexamic acid (TXA)Intravenous and oral, is equivalent oxytocin (OXY),intramuscularly, in reducing the blood loss in post partum period (mL) in patients at the end of pregnancy…
- Trial name
- TRANOXY2016 (NCT02775773)
- Testing
- Tranexamic Acid, Oxytocin
- Where
- Italy
- Volunteers
- 256 people
- Sponsor
- Azienda U.S.L. 1 di Massa e Carrara
Postpartum Haemorrhage (PPH)
The Postpartum Haemorrhage (PPH) Butterfly Work Package 3
The Postpartum Haemorrhage (PPH) Butterfly is a simple, low-cost device which has been developed as a treatment method for PPH. It will be used to stop the bleeding through compression of the uterus of women having a PPH.
- Trial name
- NCT02692287
- Testing
- The PPH Butterfly
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Andrew Weeks MD MRCOG
Delivery
Carbetocin Versus Oxytocin in the Prevention of Post Partum Haemorrhage (PPH) in Women Delivered Vaginally With at Least 2 Risk Factors for Atonic PPH: A Randomised Controlled Trial
250 women will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Carbetocin 100 µgm (Pabal® Ferring, UK) and group 2 will receive oxytocin 5IU (Syntocinon®, Novartis…
- Trial name
- PPH (NCT02304042)
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Post Partum Hemorrhage
Carbetocin in the Prevention of Primary Postpartum Haemorrhage
Postpartum haemorrhage (PPH) ranks as the first cause of maternal mortality in developing countries and it is the cause of 25% of maternal deaths worldwide.
- Trial name
- NCT06159959
- Testing
- Carbetocin
- Where
- Egypt
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Ministry of Health and Population, Egypt
Postpartum Hemorrhage
Carbetocin Versus Misoprostol in High Risk Patients for Postpartum Hemorrhage After C.S.
We will compare between Carbitocin and Misoprostol in prevention of postpartum hemorrhage in high risk patients after C.S.
- Trial name
- PPH (NCT02277067)
- Testing
- Carbetocin, Misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Postpartum Hemorrhage
Celox™ PPH for Reaching Haemostasis in Patients With Postpartum Hemorrhage
This is a post market prospective, single arm clinical investigation to continuously assess the safety performance and effectiveness of the Celox™ PPH as a uterine haemostatic tamponade treatment for uterine postpartum hemorrhage…
- Trial name
- NCT06033170
- Testing
- CELOX™ PPH
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Medtrade
Postpartum Hemorrhage
Fever After Misoprostol Administration for the Treatment of Primary Postpartum Hemorrhage
This study will evaluate side effects after sublingual misoprostol (600 mcg) as a first-line treatment for primary postpartum hemorrhage (PPH) due to suspected uterine atony.
- Trial name
- NCT01080846
- Testing
- Misoprostol
- Where
- Ecuador
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Post Partum Hemorrhage
Carbetocin Versus Ergometrine in the Management of Atonic Post Partum Haemorrhage (PPH) in Women Delivered Vaginally
200 women will be randomly divided into 2 equal groups using computer generated random numbers. Group 1 will receive Carbetocin 100 µgm (Pabal® Ferring, UK) and group 2 will receive ergometrine 0.5mg (methergin®, Novartis…
- Trial name
- NCT02410759
- Testing
- Carbetocin, Ergometrine
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Postpartum Hemorrhage, Cesarean Section
Carbetocin Versus Oxytocin for Prevention of Postcesarean Hemorrhage in Pregnancy With High Risk for PPH
Objective: study efficacy of carbtocin versus oxytocin for prevention postpartum hemorrhage in high risk pregnancy who undergo cesarean section
- Conditions
- Postpartum Hemorrhage, Cesarean Section, High Risk Pregnancy
- Trial name
- NCT04089176
- Testing
- Carbetocin, oxytocin
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Post Partum Haemorrhage
Carbetocin Versus Oxytocin in the Prevention of Post Partum Haemorrhage (PPH) in Women Undergoing Caesarean Sections for Placenta Previa: A Randomised Controlled Trial
The study aims at comparing the roles of carbetocin and oxytocin in the prevention of atonic PPH in women undergoing CS for placenta previa.
- Trial name
- NCT02303418
- Testing
- Carbetocin, Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Hemorrhage
Double Blind Placebo Controlled Bellis Perenis and Arnica Montana as a Drug for PPH
To look at the antihemmorhagic effect of 2 homeopathic drugs in women post delivery Bellis Perenis and Arnica montana
- Trial name
- NCT00405626
- Testing
- Bellis Perenis ,Arnica montana
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Postpartum Hemorrhage (PPH)
Misoprostol for Treatment of Postpartum Haemorrhage (PPH) in Home Births
Misoprostol, a prostaglandin E1 that induces uterine contractions, has been proposed as a low cost, easy-to-use option for prevention and treatment of Postpartum Haemorrhage (PPH), especially in settings where injectable…
- Trial name
- NCT01508429
- Testing
- Misoprostol
- Where
- Afghanistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Hemorrhage, Immediate Postpartum Hemorrhage
Safety and Effectiveness of the KOKO Device to Treat Primary Abnormal Postpartum Uterine Bleeding or Hemorrhage
The purpose of this study is to evaluate the safety and effectiveness of the KOKO™ device in the control and reduction of primary abnormal postpartum uterine bleeding or hemorrhage.
- Conditions
- Postpartum Hemorrhage, Immediate Postpartum Hemorrhage, Hemorrhage, Postpartum
- Trial name
- SERENE (NCT06452355)
- Testing
- KOKO Device
- Where
- 17 sites in United States
- Volunteers
- 73 people
- Sponsor
- KOKO Medical Inc.
Postpartum Hemorrhage
A Program to Evaluate Riastap® and FIBTEM® for the Early Control and Treatment of Postpartum Hemorrhage (PERFECT PPH)
In this prospective, single-center, randomized, placebo-controlled, double-blind clinical trial, parturients with primary PPH are eligible for treatment with fibrinogen concentrate following both vaginal delivery and cesarean…
- Trial name
- PERFECT PPH (NCT02528708)
- Testing
- fibrinogen concentrate
- Sponsor
- Yale University
Post-partum Hemorrhage (PPH)
Accurate Display of Postpartum Hemorrhage Using Triton (ADOPT)
A comparison of reported estimated blood loss with quantified blood loss in all patients whose medical records indicate Triton was used during their vaginal delivery.
- Trial name
- ADOPT (NCT02981758)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Hackensack Meridian Health
Postpartum Hemorrhage
Carbetocin Versus Misoprostol in Cases With Placenta Previa After C.S.
We will compare efficacy and safety of Carbetocin with Misoprostol in prevention of postpartum hemorrhage in Placenta previa women after C.S.
- Trial name
- PPH (NCT02277041)
- Testing
- Carbetocin, Misoprostol
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Postpartum Hemorrhage
Carbetocin Versus Oxytocin Plus Sublingual Misoprostol in the Management of Atonic Postpartum Hemorrhage
The objective of this study is to compare the effectiveness and safety of carbetocin vs. oxytocin plus sublingual misoprostol in the management of atonic postpartum hemorrhage (PPH)after vaginal delivery.
- Trial name
- NCT03870503
- Testing
- oxytocin, oxytocin plus misoprostol, Carbetocin
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Aswan University Hospital