Clinical trials: Postpartum Haemorrhage (PPH), active
Post-partum Hemorrhage
REBOA in Life-threatening Postpartum Hemorrhage (PPH) in Uganda
Background Maternal mortality rates in many low-income countries (LMICs) remain high. The most prominent cause is bleeding after birth, called postpartum haemorrhage (PPH).
- Trial name
- REBOA-PPH (NCT05598502)
- Testing
- REBOA, Resuscitative Endovascular Occlusion of the Aorta, National guidelines
- Where
- Uganda
- Volunteers
- 95 people
- Sponsor
- Centre For International Health
Pre-eclampsia, Oocyte Donation
PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)
The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation.
- Conditions
- Pre-eclampsia, Oocyte Donation, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia; Mild
- Trial name
- PRIOR (NCT07263490)
- Where
- 6 sites in Denmark
- Volunteers
- 462 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Postpartum Haemorrhage (PPH), PPH
EVE TRIAL , ALMA SYSTAM
abnormal bleeding after childbirth. This condition is called abnormal bleeding and becomes a condition known as postpartum hemorrhage (PPH) when worsens.
- Conditions
- Postpartum Haemorrhage (PPH), PPH, Postpartum Hemorrhage (Primary)
- Trial name
- EVE (NCT06646653)
- Testing
- Alma System
- Where
- 2 sites in United States, Israel
- Volunteers
- 50 people
- Sponsor
- ResQ Medical Ltd
Postpartum Hemorrhage
Intrauterine Balloon (Bakri©) Versus Uterine Tamponade With Chitosan Gauze (Celox PPH©) in the Management of Postpartum Hemorrhage Refractory to Medical Treatmen
Postpartum hemorrhage (PPH) remains one of the leading causes of maternal morbidity and mortality worldwide, particularly in low- and middle-income countries.
- Trial name
- NCT06996808
- Testing
- Bakri Baloon, Celox gauze
- Volunteers
- 196 people
- Sponsor
- University of Roma La Sapienza
Intact Cord Placental Delivery, Delayed Cord Clamping
Intact Cord Placental Delivery vs Delayed Cord Clamping
The management of the third stage of labour plays a critical role in neonatal transition. Uninterrupted Intact Cord Clamping (UICC), is a clinical approach where the umbilical cord remains unclamped until the placenta is…
- Conditions
- Intact Cord Placental Delivery, Delayed Cord Clamping, Standard Delayed Cord Clamping, Timing of Cord Clamping
- Trial name
- TTC (NCT07713277)
- Where
- Italy
- Volunteers
- 1,979 people, healthy volunteers welcome
- Sponsor
- Azienda ULSS 8 Berica
Teaching Innovation, Midwifery Students Education
Flipped Learning in PPH Education: Impact on Midwifery Students' Knowledge, Skills, Self-Efficacy, and Satisfaction
Maternal death refers to a woman's death due to direct or indirect causes during pregnancy, childbirth, or within 42 days postpartum.
- Conditions
- Teaching Innovation, Midwifery Students Education, Postpartum Hemorrhage, Flipped Classroom Model in Teaching
- Trial name
- NCT06861296
- Testing
- Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Postpartum Hemorrhage, Coagulation Disorder
SWIFT - SWIss Factor XIII Trial in PPH
The goal of this trial is to determine if postpartum blood loss can be reduced by replenishing coagulation factor XIII (FXIII) at an early stage of postpartum hemorrhage (PPH).
- Conditions
- Postpartum Hemorrhage, Coagulation Disorder, Coagulation Factor Deficiency, Hemorrhage
- Trial name
- SWIFT (NCT06481995)
- Testing
- Fibrogammin
- Where
- 9 sites in Switzerland
- Volunteers
- 988 people
- Sponsor
- Christian Haslinger
Thrombocytopenia, Postpartum Haemorrhage (PPH)
Prediction of Platelet Function Using Viscoelastic Test (ROTEM® Sigma) in Obstetric Anesthesia.
This prospective observational, non-interventional, single-center study aims to evaluate whether the viscoelastic parameter PLTEM, derived from ROTEM® sigma testing (EXTEM-A5 minus FIBTEM-A5), can accurately estimate platelet…
- Trial name
- NCT07616349
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Nicolas Brogly
PPH - Postpartum Hemorrhage, Eclampsia
Comparing Simulated Patients and Manikin Based Simulation in Obstetrics
The aim of this randomized study is to compare a live, trained simulated patient with a high-fidelity manikin in obstetric emergency team training using two standardized scenarios.
- Trial name
- NCT07857551
- Testing
- Trained, standardized patient, MamaAnne Patient Simulator
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Postpartum Hemorrhage, Treatment Outcome
Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum Hemorrhage
This study will investigate all women treated with vacuum-induced tamponade (VIT) for PPH at a tertiary center, namely at the University Hospital Zurich (USZ), over a nine-year period (2017-2025).
- Conditions
- Postpartum Hemorrhage, Treatment Outcome, Pregnancy Outcome
- Trial name
- LOVIT (NCT07885072)
- Where
- Switzerland
- Volunteers
- 380 people
- Sponsor
- University of Zurich