Clinical trials: Postpartum Hemorrhage
Postpartum Hemorrhage, Blood Loss
Carbetocin Versus Syntometrine for Prevention of Postpartum Hemorrhage After Cesarean Section
to compare effectiveness and tolerability of carbetocin versus syntometrine in prevention of Postpartum hemorrhage after cesarean section
- Trial name
- NCT02044549
- Testing
- carbetocin, Syntometrine
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postpartum Hemorrhage
Tranexamic Acid to Prevent Heavy Bleeding After Childbirth in Women At Higher Risk
Heavy bleeding after childbirth, known as a postpartum haemorrhage (PPH), causes about 70,000 maternal deaths every year. Tranexamic acid (TXA) is a lifesaving treatment for women with PPH.
- Trial name
- I'M-WOMAN (NCT05562609)
- Testing
- Tranexamic acid
- Where
- Tanzania
- Volunteers
- 30,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Cerebral Vein Thrombosis
Rivaroxaban vs. Warfarin in CVT Treatment
Cerebral venous thrombosis (CVT) is an uncommon venous-type of stroke tends to affect younger patients with somewhat different risk factors and much better outcome compared to arterial strokes.
- Trial name
- RWCVT (NCT04569279)
- Testing
- Rivaroxaban, Warfarin
- Where
- Syria
- Volunteers
- 71 people
- Sponsor
- Damascus University
Hemorrhage
RCT of Zhi Byed 11 (ZB11) Versus Misoprostol in Tibet
Previous research has confirmed that hemorrhage is among the most commonly encountered pregnancy complications in the Tibet Autonomous Region (TAR).
- Trial name
- NCT00147420
- Testing
- Zhi Byed 11
- Where
- 3 sites in China
- Volunteers
- 848 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Postpartum Hemorrhage
TRAnexamic Acid for Preventing Postpartum Hemorrhage Following a Cesarean Delivery
The aim is to assess the impact of tranexamic acid (TXA) for preventing postpartum hemorrhage (PPH) following a cesarean section (CS).
- Trial name
- TRAAP2 (NCT03431805)
- Testing
- Tranexamic Acid Injectable Solution, Sodium Chloride 0.9%
- Where
- 26 sites in France
- Volunteers
- 4,574 people
- Sponsor
- University Hospital, Bordeaux
Post Partum Hemorrhage
Amr Maneuver for Prevention of Postpartum Hemorrhage
The patients were divided randomly in to 2 GROUPS: control group: 153 patients received Oxytocin 10 IU I.V shot administered at the time of delivery of the anterior shoulder of the baby according to the WHO recommendation for…
- Trial name
- NCT04401839
- Testing
- Oxytocin IV shot, Oxytocin IV drip, Amr maneuver
- Where
- Egypt
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postpartum Haemorrhage
Bimanual Uterine Compression to Reduce Blood Loss and Prevent Postpartum Haemorrhage After Vaginal Delivery
the investigators aim to compare bimanual uterine compression immediately after delivery of the placenta for 5 minutes versus no intervention for the prevention of postpartum hemorrhage in Women at high risk for primary atonic…
- Trial name
- NCT02136719
- Testing
- bimanual uterine compression
- Where
- Egypt
- Volunteers
- 520 people
- Sponsor
- Benha University
Postpartum Hemorrhage
Carbetocin Versus Oxytocin Plus Sublingual Misoprostol in the Management of Atonic Postpartum Hemorrhage
The objective of this study is to compare the effectiveness and safety of carbetocin vs. oxytocin plus sublingual misoprostol in the management of atonic postpartum hemorrhage (PPH)after vaginal delivery.
- Trial name
- NCT03870503
- Testing
- oxytocin, oxytocin plus misoprostol, Carbetocin
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Aswan University Hospital
Post Partum Hemorrhage, Asphyxia; Fetal
Evaluation of Maternal & Newborn Health Simulation Lab Centers of Excellence in Nepal
Postpartum hemorrhage and birth asphyxia are the leading causes of maternal and neonatal mortalities worldwide. Prevention and adequate treatment are, therefore crucial.
- Conditions
- Post Partum Hemorrhage, Asphyxia; Fetal, Maternal-Fetal Relations
- Trial name
- SLAB (NCT06577922)
- Testing
- Establishment of a simulation lab and provision of simulation based trainings
- Where
- Nepal
- Volunteers
- 1,464 people, healthy volunteers welcome
- Sponsor
- One Heart Worldwide
Postpartum Hemorrhage
Management of Postpartum Haemorrhage and Effect of Geographic Region
Background: Maternal deaths occur universally and are largely avoidable. Postpartum haemorrhage accounts for a disproportionate amount of maternal deaths.
- Trial name
- NCT03166839
- Testing
- Experiencing PPH
- Volunteers
- 20,060 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Health Care Cost, Post Partum Haemorrhage
Health Economics Evaluation of the Management of Severe Postpartum Hemorrhage: Comparison of Recombinant Activated Factor VII Strategy to the Reference Strategy
The main objective of this project is to assess the average cost of the treatment of bleeding postpartum with recombinant activated factor VII (NovoSeven®) and compare it to the reference strategy.
- Trial name
- NCT02900690
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Postpartum Hemorrhage
Carbetocin at Elective Cesarean Delivery
Post-partum hemorrhage (PPH) is a major cause of maternal death worldwide. Oxytocin is the most commonly uterotonic drug used to prevent and treat PPH in North America, however, there are some limitations to its use.
- Trial name
- NCT01262742
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Bleeding, Anemia
Carbetocin Versus Oxytocin and Ergometrine for the Prevention of Postpartum Haemorrhage Following Caesarean Section
The investigators compare the effectiveness and adverse effects of I.V carbetocin versus oxytocin \& ergometrine I.V for prevention of postpartum haemorrhage following cesarean section.
- Trial name
- NCT02101567
- Testing
- Pabal 100 mcg iv infusion over 1 minute given after delivery of fetal head, Oxytocin 5 IU iv infusion and Methtergine 0.2 mg iv
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Postpartum Hemorrhage, Systemic Autoimmune Diseases
Risk Factors for Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the most significant leading cause of pregnancy-related mortality in high-risk cesarean delivery women.
- Trial name
- NCT06730919
- Testing
- Estimated Blood Loss after cesarean delivery within 24 h
- Where
- 5 sites in China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Postpartum Hemorrhage
Tranexamic Acid and Ethamsylate For Preventing PPH in Patient Undergoing LSCS at High Risk For PPH
The aim of this study is to compare the effect of low dose of Tranexamic acid (1gm) and Ethamsylate (1gm) after prophylactic oxytocin administration versus placebo with prophylactic oxytocin given in the 2 minutes after child…
- Trial name
- NCT02604719
- Testing
- Tranexamic Acid and Ethamsylate
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ahmed Alanwar
Postpartum Hemorrhage
Safety and Effectiveness of the Jada System in Treating Primary Postpartum Hemorrhage
The purpose of this study is to evaluate the safety and effectiveness of the Jada System in the control and reduction of primary postpartum hemorrhage.
- Trial name
- PEARLE (NCT02883673)
- Testing
- Jada System
- Where
- 15 sites in United States
- Volunteers
- 107 people
- Sponsor
- Alydia Health
Postpartum Haemorrhage
The Influence of Placental Drainage of Management of the Third Stage of Labor:a Randomized Controlled Study
To determine whether early placental drainage plus cord traction reduces the incidences of manual removal and blood loss, and to determine the risk factors associated with blood loss after delivery.
- Trial name
- NCT01931423
- Testing
- Placental cord drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 485 people
- Sponsor
- Istanbul Bakirkoy Maternity and Children Diseases Hospital
Postpartum Hemorrhage,
Does Mednav, a Medical Navigation System, Aid Non-technical and Technical Skills in the Simulated Obstetric Emergency?
It is well known that medical errors account for a large amount of patient harm within the hospital setting. This is a significant problem within the emergency context.
- Trial name
- NCT02783131
- Testing
- MedNav
- Volunteers
- 266 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Postpartum Hemorrhage
Misoprostol for Treatment of Postpartum Hemorrhage at Community-level Births in Egypt
This randomized controlled community-based trial will assess the effectiveness of administration of 800 mcg sublingual misoprostol with standard of care vs.
- Trial name
- NCT01619072
- Testing
- Misoprostol + referral
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects