Clinical trials: Postpartum Infection
Influenza, Vaccine
Influenza Vaccine Postpartum Questionnaire
The purpose of this trial is to assess the knowledge and attitudes of post-partum women regarding influenza and the use of the influenza vaccine in pregnancy.
- Conditions
- Influenza, Vaccine, Pregnancy
- Trial name
- NCT00401700
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pertussis/Whooping Cough, Influenza Viral Infections
Influenza and Pertussis Vaccination Status of Women in Immediate Postpartum and Caregivers
Pertussis is a bacterial respiratory infection caused by Bordetella pertussis. Highly contagious, it is potentially serious and even fatal in infants under 6 months of age.
- Trial name
- COVAGRIP (NCT05234229)
- Testing
- Survey
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Central Hospital, Nancy, France
Drug Pharmacokinetics in Healthy Volunteers
Postpartum 8-aminoquinoline Breast Milk Study
In Papua New Guinea, administration of primaquine (PQ) or tafenoquine (TQ) to breastfeeding mothers is contraindicated during the first six months postpartum, when infants are recommended to be exclusively breastfed, because of a…
- Trial name
- NCT07060404
- Testing
- Daily primaquine (0.5 mg/kg per day) for 14 days given with food food and water, Daily primaquine 1 mg/kg per day for 7 days given with food and water, Single-dose tafenoquine given with food and water to prevent gastrointestinal discomfort
- Where
- Papua New Guinea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Curtin University
Appendicitis Acute, Cesarean Wound Disruption With Postnatal Complication
Are Cesarean Section and Appendectomy in Pregnancy and Puerperium Interrelated?
It is not known whether appendectomy for acute appendicitis (AA) increases the Cesarean section (CS) rate and whether CS increases the likelihood of AA and appendectomy in the early puerperium.
- Trial name
- APPENDECTOMY (NCT04876547)
- Testing
- appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Amasya University
HIV Infection, Pregnancy
Evaluation of Barriers to Postpartum Care in HIV Infected Women
The purpose of this study is to evaluate why the majority of HIV infected women in the Harris County Health District system who are pregnant do not come to clinic for their HIV disease after they have a baby through questionaires…
- Trial name
- NCT01853917
- Testing
- questionaires and structured interviews
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- The University of Texas Health Science Center, Houston
Preeclampsia, Hypertensive Disorder of Pregnancy
Cardiovascular Protection After Preeclampsia With Enalapril
The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.
- Conditions
- Preeclampsia, Hypertensive Disorder of Pregnancy, Hypertension, Gestational Hypertension
- Trial name
- CAPP-E (NCT07222852)
- Testing
- Enalapril, Standard treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Women and Infants Hospital of Rhode Island
HIV Infections
Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy
IMPAACT P1026s is a Phase IV prospective clinical study to evaluate the pharmacokinetics (PKs) of antiretroviral (ARV) and tuberculosis (TB) medications in pregnant women and their infants.
- Trial name
- NCT00042289
- Testing
- atazanavir/cobicistat, darunavir/ritonavir dosage #1, darunavir/ritonavir dosage #2
- Where
- 62 sites in United States, Argentina and 6 more
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Tuberculosis
Evaluating PK, Tolerability, and Safety of Rifapentine and Isoniazid in Pregnant and Postpartum Women
The purpose of this study was to evaluate the pharmacokinetics (PK), tolerability, and safety of once-weekly doses of rifapentine (RPT) and isoniazid (INH) in HIV-1-infected and HIV-1-uninfected pregnant and postpartum women with…
- Trial name
- NCT02651259
- Testing
- Rifapentine (RPT), Isoniazid (INH), Pyridoxine (vitamin B6)
- Where
- 5 sites in Haiti, Kenya and 3 more
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gestational Diabetes Mellitus (GDM), Non-communicable Chronic Diseases
Long-term Evaluation of Gestational Endocrine & Metabolic Dynamics
Gestational diabetes mellitus (GDM) is the most common complication and metabolic disorder during pregnancy, with clear risks to both the mother and fetus.
- Trial name
- LEGEND (NCT07119177)
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Yang ZHANG
Pregnancy, Premature Birth
Development of a Nationally Scalable Model of Group Prenatal Care to Improve Birth Outcomes: "Expect With Me"
This study addresses the intractable challenges of adverse birth outcomes, including preterm delivery and low birthweight, by proposing the development, implementation and evaluation of a model of group prenatal care that could…
- Conditions
- Pregnancy, Premature Birth, Infant, Low Birth Weight, Postpartum Period
- Trial name
- NCT02169024
- Testing
- Expect With Me group prenatal care, Standard individual prenatal care
- Where
- 2 sites in United States
- Volunteers
- 2,402 people, healthy volunteers welcome
- Sponsor
- Yale University
Influenza
Post-Partum Immunization With Live Attenuated Influenza Vaccine (LAIV) or Trivalent Influenza Vaccine (TIV) in Post-Partum Breast Feeding Women
The purpose of this research study is to learn more about the safety of 2 licensed flu vaccines, nasal spray and flu vaccine shot, in mothers and their infants, when given to women who are breastfeeding and to compare the immune…
- Trial name
- NCT01181323
- Testing
- Cold-adapted live attenuated influenza virus vaccine, trivalent, Trivalent inactivated influenza vaccine
- Where
- 6 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Coccidioidomycosis
To Find Effectiveness of Stretching Versus Soft Tissue Mobilization in Coccydynia in Postpartum Females
This research is to determine the effectiveness of stretching versus soft tissue mobilization in coccydynia patients.The main purpose of the study is the the development of evidence based therapeutic protocols for postpartum…
- Trial name
- NCT06913803
- Testing
- Stretching, Soft Tissue Mobilization
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Superior University
Hiv
Stepped Care to Optimize PrEP Effectiveness in Pregnant and Postpartum Women
To reach HIV-uninfected pregnant and breastfeeding women in South Africa, who are at very high risk of HIV, researchers will test a new and innovative package of interventions: 1) pre-exposure prophylaxis (PrEP), which is a daily…
- Trial name
- SCOPE-PP (NCT05322629)
- Testing
- PrEP adherence biofeedback, Standard of care counseling
- Where
- South Africa
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chagas Disease, Lactation
Study of Benznidazole Transfer Into Breastmilk in Lactating Women With Chagas Disease
The investigators propose to study the transfer of benznidazole into breastmilk from the blood of lactating women who receive the drug for the treatment of Chagas disease.
- Trial name
- LACTBENZ (NCT01547533)
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Hospital de Niños R. Gutierrez de Buenos Aires
Uterine Leiomyoma
Postpartum Uterine Regression
Uterine leiomyomas are the leading cause of hysterectomy in the United States, accounting for over 200,000 procedures each year.
- Trial name
- NCT00341848
- Where
- United States
- Volunteers
- 374 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections
Postpartum infection if a major cause of maternal morbidity and mortality and surgical site infections are some of the common complications following cesarean section.
- Conditions
- Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
- Trial name
- NCT05392400
- Testing
- Steri3X, Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Hypertensive Disorder of Pregnancy, Pre-Eclampsia
Optimal Blood Pressure Treatment Thresholds Postpartum
The objective of this research project is to conduct a single-site pilot trial within our institution's clinical remote blood pressures (BP) management program to assess the feasibility and effect of tight blood pressure control…
- Conditions
- Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia
- Trial name
- NCT06069102
- Testing
- Usual care, Tight blood pressure control
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Alisse Hauspurg
Pregnancy
Matrix Metalloproteinases's in Oral Biofluids During Pregnancy and Postpartum
The aim of this study was to investigate salivary and gingival crevicular fluid (GCF) levels of MMP-8, MMP-9 and TIMP-1 during 2/3 trimester of pregnancy and after delivery
- Trial name
- NCT03516565
- Testing
- Saliva collection, GCF collection
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
HIV/AIDS
CareConekta: A Pilot Study of a Smartphone App in South Africa
Population mobility is frequent in South Africa and disrupts the continuity of HIV care. Postpartum, HIV-positive women are at elevated risk of dropping out of HIV care and are highly mobile.
- Trial name
- NCT03157908
- Testing
- CareConekta
- Where
- South Africa
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center