Clinical trials: Postpartum Mood Disorder
Depression, Depression, Postpartum
Randomized Controlled Trial of the Alma Peer Mentoring Program for Pregnant Women Experiencing Depression
Women have double the odds of getting depressed as men and commonly experience depression during the childbearing and early parenting years. Many new and expectant mothers who experience depression never receive help.
- Trial name
- NCT02883686
- Testing
- Alma
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Colorado, Boulder
Depression, Pregnancy Related
How Does Mindful Mood Balance for Moms Work?
The purpose of this investigation is to conduct a randomized trial comparing a web-based Mindful Mood Balance for Moms course without coaching support to waitlist control among pregnant or early parenting women with depression…
- Conditions
- Depression, Pregnancy Related, Antenatal Depression, Depression, Postpartum
- Trial name
- NCT05000879
- Testing
- MMB for Moms
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Boulder
Postpartum Depression
Escitalopram (Lexapro) for the Treatment of Postpartum Depression
The purpose of this study is to determine whether women with postpartum major depressive disorder (MDD) will experience a significant decrease in depressive symptoms from baseline over an eight-week treatment intervention with…
- Trial name
- LexaproPPD (NCT00833469)
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Depression, Postpartum
The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience
Magnesium is sometimes used to prevent seizures in the setting of hypertensive disorders of pregnancy. The primary aim of this study is to determine if women who receive magnesium are less likely to experience postpartum…
- Trial name
- NCT02454322
- Testing
- Magnesium Sulfate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Perinatal Problems, Post Traumatic Stress Disorder
Initial Intervention Efficacy for an Online PTSD Intervention for Pregnant Women
The current study aims to test a brief computer-assisted intervention (psychoeducation + skills) for pregnant women with elevated PTSD symptoms.
- Conditions
- Perinatal Problems, Post Traumatic Stress Disorder, Post Partum Depression
- Trial name
- NCT04264520
- Testing
- PTSD Psychoeducation + Skills Intervention
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Postpartum Depression (PPD), Postpartum Anxiety
Online Transdiagnostic Group CBT for Postpartum Depression and Anxiety
The purpose of this pilot study is to test the feasibility of an online 10-Week group cognitive behavioural therapy (CBT; a type of talking therapy) intervention for postpartum depression and anxiety that is led by…
- Trial name
- NCT07162129
- Testing
- Cognitive Behavioral Therapy for Postpartum Depression (PPD) and Anxiety
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McMaster University
Postoperative Pain, Postpartum Depression
Dose Low Dose Ketamine in Casesarian
The results of ketamine, ketamine and midazolom can be copied after birth in cesareans subjected to spinal anesthesia.
- Trial name
- ketamine (NCT06237569)
- Testing
- Application of ketamine and midazolam or ketamine alone to patients undergoing cesarean section under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Inonu University
Postnatal Depression
Studies of Mothers With Postnatal Depression
This study investigates the effects of a single dose of oxytocin (OT) delivered via a nasal spray in women with and without traits of postnatal depression (PND).
- Trial name
- NCT04745494
- Testing
- OT administration
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University College, London
Depression, Anxiety Disorders
Effects of Interpersonal Psychotherapy on Depression During and After Pregnancy
This study will evaluate the impact of interpersonal psychotherapy on the course of depression during and after pregnancy, as well as its effect on infant birth outcomes.
- Trial name
- NCT00380419
- Testing
- Interpersonal Psychotherapy (IPT)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Post Partum Depression, Perinatal Depression
mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression
Postpartum depression (PPD) is associated with significant health consequences for mothers and children, and the current COVID-19 pandemic has had a major impact on the mental health of particularly vulnerable populations…
- Trial name
- NCT05186272
- Testing
- Stress reduction program 'A', Stress reduction program 'B'
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Kaiser Permanente
Breastfeeding Self-efficacy, Maternal Attachment
The Effect Of Postpartum Therapeutıc Touch On Breastfeedıng Self-Effıcacy, Maternal Attachment, And Postpartum Depressıon In Prımıparous Women: A Randomızed Controlled Study
The postpartum period, also known as the fourth trimester, begins with the birth of the baby and lasts approximately 6-8 weeks, varying from person to person.
- Trial name
- NCT07693010
- Testing
- therapeutic touch, terapötik dokunma
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Depression, Postpartum
Estimating the Prevalence of Postpartum Anxiety and Depression in the Context of the Coronavirus Disease (COVID-19) Pandemic
In December 2019, infection with a new coronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in China and has since spread throughout the world.
- Trial name
- PsyCOVIDUM (NCT04852757)
- Where
- France
- Volunteers
- 2,580 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Parenting Self-efficacy, Postpartum Anxiety
Essential Coaching Postpartum: Evaluating a Parent-focused Postpartum Text Message Program in Nova Scotia
The transition to parenthood is often an exciting yet hard period for parents. In the first year after a new baby, many parents feel less confident, have more anxiety and depression, and feel more isolated and alone.
- Conditions
- Parenting Self-efficacy, Postpartum Anxiety, Postpartum Depression (PPD), Postpartum Stress
- Trial name
- NCT06996067
- Testing
- Essential Coaching Postpartum
- Where
- Canada
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Pregnancy
Nutritional Status and Mental Health During Pregnancy and Postpartum: a Cohort Study in Rio de Janeiro, Brazil
There is increasing evidence that psychosocial factors may affect health by means of biological effects and changes in behavioral health.
- Trial name
- NCT01660165
- Where
- Brazil
- Volunteers
- 299 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Perinatal Depression, Post Partum Depression
Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model
The proposed study involves experimentally manipulating reproductive hormones in nonpregnant, euthymic women to create a scaled down version of the changes that occur during pregnancy and the postpartum period.
- Conditions
- Perinatal Depression, Post Partum Depression, Depression, Postpartum, Depression
- Trial name
- NCT04051320
- Testing
- Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infant, Newborn, Maternal Outcome
The Half Swaddling Application on Infant Sleep Routine, Maternal Sleep Quality, Depression
In this prospective controlled study, it was aimed to examine the effects of half swaddling in term infants on infant sleep routine, maternal sleep quality and postpartum depression.
- Trial name
- Half swaddling (NCT06750796)
- Testing
- The Half Swaddling Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tanta University
Lactation Suppressed, Cabergoline Adverse Reaction
Factors and Outcomes Associated With Postpartum Cabergoline Use
Cabergoline is frequently being requested by many postpartum women with a live newborn to suppress lactation. The aim of the study is to investigate which women desire such an intervention, and what side effects they are…
- Conditions
- Lactation Suppressed, Cabergoline Adverse Reaction, Postpartum DVT, Postpartum Depression
- Trial name
- NCT03965572
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laniado Hospital
Postpartum Depression, Postpartum Anxiety
The Maternal Well-Being Study
This project aims to understand the local feasibility and acceptability of MamaMeals (a home-delivered nutritious, postpartum meal delivery program) and MamaMatters (a moderated social media-based peer support group) among…
- Conditions
- Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
- Trial name
- MWB (NCT05484999)
- Testing
- Meals, Meals + Social Support, Control
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center