Clinical trials: Postpartum Period, open to volunteers
Gestational Diabetes
Pilot Study of Continuous Glucose Monitoring for Postpartum Glucose Screening
The oral glucose tolerance test (OGTT) is the standard of care in the postpartum period to screen patients with gestational diabetes mellitus (GDM) for persistent dysglycemia.
- Trial name
- NCT07332416
- Testing
- Continuous glucose monitoring for 14 days using the Freestyle LibrePro by Abbott
- Where
- United States
- Volunteers
- 1,300 people
- Sponsor
- Wake Forest University Health Sciences
Postpartum, Mothers
The Effect of Laughter Therapy on Marital Adjustment, Life Satisfaction and Maternal Attachment Level in Mothers
The postnatal period is a fragile period with physical and psychological changes as well as hormonal changes in the mother. Mind-body based complementary practices such as yoga, meditation, relaxation exercises can be used to…
- Trial name
- NCT06917417
- Testing
- Laughter Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Severe Pain, Cesarean Section Complications
Empowered Relief for Severe Pain After Cesarean Delivery During the Inpatient Period
This pilot feasibility study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain management intervention, to postpartum patients experiencing severe pain following cesarean…
- Conditions
- Severe Pain, Cesarean Section Complications, Postpartum, Chronic Pain
- Trial name
- NCT07832240
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Stanford University
Pain, Labor
Effect of Foot Reflexology on Postpartum Afterpains
This study will be conducted to determine the effect of foot reflexology on afterpains after normal labor.
- Trial name
- NCT06951750
- Testing
- Reflexology, general foot massage
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Gestational Hypertension, Hypertension in Pregnancy
A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)
This trial is a pilot-scale, single institution randomized, placebo-controlled trial to assess the feasibility, acceptability, and efficacy of administering dapagliflozin for cardiovascular risk reduction in the postpartum…
- Conditions
- Gestational Hypertension, Hypertension in Pregnancy, Pre-Eclampsia, Superimposed Pre-Eclampsia
- Trial name
- DAPA-HP (NCT06785116)
- Testing
- Dapagliflozin 10mg Tab
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Michigan
Post Partum Haemorrhage
Outcomes and Perceptions of the Implementation of the JADA Device in a Stage II Postpartum Hemorrhage Management Protocol in Referral Hospitals of the Colombian Pacific Region
This study focuses on postpartum hemorrhage (PPH), a condition that stands out as the leading cause of global maternal mortality. Annually, about 14 million women experience PPH, resulting in approximately 70,000 deaths.
- Trial name
- JADAValle (NCT06843265)
- Testing
- Vacuum- Induce Hemorrhage Control
- Volunteers
- 24 people
- Sponsor
- Fundacion Clinica Valle del Lili
Stress Urinary Incontinence
Impact of Virtual Reality Pelvic Floor Training on Postpartum Stress Urinary Incontinence
This study will be conducted to determine the effect of virtual reality (VR) on pelvic floor training on postpartum stress urinary incontinence (SUI) .
- Trial name
- NCT07455838
- Testing
- Pelvic floor muscle rehabilitation supported by an immersive VR, Medical treatment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postpartum Depression (PPD), Postpartum Anxiety
Investigation of TVNS Administration on Postpartum Mental Health
The aim of the study is to explore whether transcutaneous vagus nerve stimulation (tVNS) may be effective in preventing mood swings and depressive symptoms in the postpartum phase, as well as serving as a supplementary…
- Conditions
- Postpartum Depression (PPD), Postpartum Anxiety, Postpartum Sadness, Postpartum Blues
- Trial name
- NCT06682689
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Depression, Postpartum
Effect of Peripartum 40 Hz Audiovisual Stimulation on Postpartum Depression in Women Undergoing Elective Cesarean Section: A Randomized Clinical Trial
Postpartum depression (PPD) is a common mental health condition affecting 10%-30% of new mothers, with serious consequences for both mother and child.
- Trial name
- NCT07807462
- Testing
- 40 Hz Audiovisual Stimulation
- Where
- China
- Volunteers
- 204 people
- Sponsor
- The First People's Hospital of Lianyungang
Perinatal Depression, Post Partum Depression
Accelerated TMS for Perinatal Depression
We are studying a treatment for depression called accelerated Transcranial Magnetic Stimulation (TMS) among pregnant and postpartum individuals.
- Conditions
- Perinatal Depression, Post Partum Depression, Major Depressive Disorder
- Trial name
- PAiNT (NCT06968390)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brigham and Women's Hospital
Postpartum Hemorrhage, Uterine Atony
Exteriorization Versus In Situ Hysterotomy Repair During Cesarean: Effects on Uterine Tone
During standard cesarean deliveries, there are two ways that obstetricians repair the incision on the uterus (hysterotomy after delivery of the baby.
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Uterine Atony With Hemorrhage, Cesarean Section
- Trial name
- NCT07606846
- Testing
- Test Intervention: In Situ Repair, Comparator Intervention: Exteriorization
- Volunteers
- 60 people
- Sponsor
- Stanford University
Perineal Trauma, Postpartum Pain
RELIEVE Study- Platelet-Rich Plasma to Reduce Postpartum Pain After Perineal Tears or Episiotomy
Perineal tears and episiotomies are common after vaginal birth and may cause persistent pain, impaired wound healing, pain during sexual activity, and concerns about genital appearance.
- Conditions
- Perineal Trauma, Postpartum Pain, Episiotomy, Perineal Laceration
- Trial name
- RELIEVE (NCT07727213)
- Testing
- Autologous Non-Activated Platelet-Rich Plasma, Saline (0.9%, sterile, for infusion)
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University Hospital, Geneva
Postpartum Comfort, Postpartum Care
THE EFFECT OF REIKI ON BREASTFEEDING, PAIN AND COMFORT AFTER CESAREAN SECTION
EFFECT OF REİKİ APPLİED DURİNG THE POSTPARTUM PERİOD ON BREASTFEEDİNG, PAİN, AND COMFORT IN WOMEN WHO DELİVERED BY CESAREAN SECTİON The aim of this randomized controlled trial is to determine the effect of Reiki applied to…
- Conditions
- Postpartum Comfort, Postpartum Care, Cesarean Section Pain, Breastfeeding Self-Efficacy
- Trial name
- NCT07447609
- Testing
- reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Saglik Bilimleri Universitesi
Ultomiris-exposed Pregnant/ Postpartum, Pregnancy
Study of Ultomiris® (Ravulizumab) Safety in Pregnancy
The primary objective of this study is to describe the frequency and characteristics of pregnancy outcomes and maternal complications among participants exposed to Ultomiris and to describe the frequency and characteristics of…
- Conditions
- Ultomiris-exposed Pregnant/ Postpartum, Pregnancy, Paroxysmal Nocturnal Hemoglobinuria (PNH), Atypical Hemolytic Uremic Syndrome (aHUS)
- Trial name
- NCT06312644
- Testing
- Ultomiris
- Where
- 7 sites in United States, Australia and 5 more
- Volunteers
- 75 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Well-Being, Psychological
Evaluation of Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 for Postpartum Women
There is no widely used, statistically validated assessment for physical and mental health for the short- to medium-term in a postpartum population.
- Trial name
- NCT06002763
- Testing
- PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System), WHOQoLBREF (World Health Organization Quality of Life Brief Version), EQ-5D-3L1 (not an acronym)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postpartum Perineal Care, Peer Mentoring
THE EFFECT OF PEER MENTORING ON THE KNOWLEDGE, SKILLS, AND METACOGNITIVE THINKING SKILLS OF NURSING STUDENTS ON POSTPARTUM PERINEAL CARE: AN EXPERIMENTAL TRIAL WITH ONE-GROUP PRETEST-POSTTEST DESIGN
Postpartum perineal care (PPC) is one of the critical skills that should be acquired by students studying in Obstetrics and Gynaecology Nursing under nursing education.
- Trial name
- Perineal care (NCT06926309)
- Testing
- Peer mentoring
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Gestational Diabetes Mellitus (GDM), Diabetes Type 2
Pregnancy and Postpartum Breastfeeding Support for Patients With Gestational Diabetes
The investigators will use implementation methods to develop better breastfeeding support for patients with gestational diabetes as a way to prevent type 2 diabetes.
- Conditions
- Gestational Diabetes Mellitus (GDM), Diabetes Type 2, Breastfeeding Continuation, Breastfeeding Support
- Trial name
- NCT07176793
- Testing
- Implementation mapping to develop a multilevel health system strategy for prevention of type 2 diabetes through targeted breastfeeding support for patients with gestational diabetes
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Depression, Postpartum, Postpartum Depression (PPD)
Brexanolone Lifting Outcomes Of Moms
The purpose of this research study is to test the study drug, LPCN 1154A, as a possible treatment for postpartum depression (PPD).
- Conditions
- Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression
- Trial name
- BLOOM (NCT07822321)
- Testing
- LPCN 1154A
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Lipocine Inc.
Gestational Diabetes
Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes
The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in…
- Trial name
- NCT05917587
- Testing
- Metformin Hydrochloride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anna Stanhewicz, PhD