Clinical trials: Postpartum Period
Postpartum Hemorrhage
Misoprostol for the Treatment of Postpartum Hemorrhage
The purpose of this study is to test whether misoprostol is as effective as oxytocin for treating primary postpartum hemorrhage (PPH) with uterine atony as the suspected cause in two circumstances: 1) where women have received…
- Trial name
- NCT00116350
- Testing
- Misoprostol, Oxytocin
- Where
- 6 sites in Burkina Faso, Ecuador and 3 more
- Volunteers
- 1,786 people
- Sponsor
- Gynuity Health Projects
Bloodloss in Pregnancy
Evaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini
Anaemia in pregnant women occurs at a haemoglobin (Hb) concentration <11 g/dL and treatment is essential to prevent increased maternal morbidity, fetal morbidity and mortality.
- Trial name
- NCT06201910
- Testing
- Observation of Blood loss
- Where
- 2 sites in Germany
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- Goethe University
Pregnancy, Postpartum
BUMPP: A Study to Better Understand Mood During the Perinatal Period
The overall goal of the BUMPP study is to improve our understanding of a range of moods, feelings, and thoughts that women can experience during pregnancy and soon after they give birth.
- Conditions
- Pregnancy, Postpartum, Mental Health Issue
- Trial name
- BUMPP (NCT05537259)
- Testing
- Observation Group
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of Minnesota
Postpartum Fever, Ileus
Comparison of Extraperitoneal and Intraperitoneal Cesarean Technique
Cesarean section will performed via intraperitoneally and extraperitoneally. During postoperative period pain, need for analgesia, respiratory function tests, ileus, bowel movement, discharged time will be compared.
- Conditions
- Postpartum Fever, Ileus, Hemorrhage, Pain
- Trial name
- NCT02760290
- Testing
- Extraperitoneal cesarean section, Intraperitoneal cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Prenatal Depression, Ketamine
Low-dose S-ketamine in Women With Prenatal Depression
Prenatal depression is an important risk factor of postpartum depression. Low-dose ketamine has been used for depression treatment. As a stereoisomer of ketamine, s-ketamine has similar effects to ketamine in anti-depression.
- Conditions
- Prenatal Depression, Ketamine, Postpartum Depression
- Trial name
- NCT04414943
- Testing
- S-ketamine
- Where
- 7 sites in China
- Volunteers
- 364 people
- Sponsor
- Peking University First Hospital
Puerperal Sepsis
Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women
Postpartum infections are among the leading causes of maternal mortality world-wide, particularly in under-resourced countries. Available data suggests that HIV infected women are at greater risk of postpartum complications than…
- Trial name
- NCT00343317
- Where
- South Africa
- Volunteers
- 1,372 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Smoking ( Cigarette), Breastfeeding
Prevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding Promotion
The objective of this randomized controlled trial is to examine the efficacy of a new intervention to prevent postpartum smoking relapse and related health consequences through breastfeeding promotion.
- Trial name
- NCT07661550
- Testing
- Breastfeeding promotion
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Depression, Pregnancy
Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development --- How is Paternal Psychopathology Involved?
This study aims at investigating the effects of maternal depressive symptomatology on pregnancy outcomes and newborn development. How paternal psychopathology is involved in the association will also be explored.
- Trial name
- NCT01280474
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Blood Loss, Surgical, Blood Loss, Postoperative
Tranexamic Acid Versus Misoprostol to Reduce Blood Loss During and After Cesarean Section
Brief Summary The goal of this clinical trial is to compare two medicines, intravenous tranexamic acid and rectal misoprostol, for reducing blood loss in women undergoing cesarean section.
- Conditions
- Blood Loss, Surgical, Blood Loss, Postoperative, Cesarean Section
- Trial name
- NCT07712510
- Testing
- Intravenous Tranexamic Acid, rectal misoprostol
- Where
- Pakistan
- Volunteers
- 214 people
- Sponsor
- Medicare Hospital (Pvt) Limited
Postoperative Analgesia
Quadratus Lumborum in Cesarean Section Trial
Postoperative pain of a caesarean section may be of high intensity, especially in the first 48 hours after the procedure, which affects the mother / newborn relationship, in addition to having the potential to progress to chronic…
- Trial name
- QUALICS (NCT03673280)
- Testing
- Quadratus Lumborum Block
- Where
- Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Diastasis, Diastasis Recti
Diastasis Recti Abdominis and a Combined Treatment With Abdominal Exercise and Radiofrequency
Diastasis recti abdominis is a pathology that appears in a high percentage of women during the postpartum period. However, there is little evidence about its treatment.
- Conditions
- Diastasis, Diastasis Recti, Diastasis Recti and Weakness of the Linea Alba, Diastasis Recti Abdominis
- Trial name
- NCT06214650
- Testing
- Radiofrequency, Control
- Volunteers
- 44 people
- Sponsor
- University of Castilla-La Mancha
Neonatal Care
Mobile Health Intervention to Improve Neonatal Care Practice
Effectiveness of interactive mobile health intervention (IMHI) to improve neonatal care practice among postpartum women in Dessie and Kombolcha town zones, north east Ethiopia: behavioral cluster randomized control trial.
- Trial name
- NCP (NCT05666050)
- Testing
- Mobile health intervention
- Where
- Ethiopia
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Wollo University
Childbirth-related PTSD, PTSD
International Survey of Childbirth-Related Trauma - Swedish Part
The goal of this cross-sectional observational study is to analyze childbirth-related PTSD, traumatic birth experiences and stress symptoms postpartum.
- Conditions
- Childbirth-related PTSD, PTSD, Postnatal Depression, Fear of Childbirth
- Trial name
- SwIntersect (NCT06207916)
- Where
- Sweden
- Volunteers
- 619 people
- Sponsor
- Region Östergötland
Opioid Use Disorder, Pregnancy Related
Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD
The primary objective of this study is to evaluate the ability of TOME to increase Medication for Opioid Use Disorder (MOUD) and opioid-overdose knowledge in pregnant and postpartum persons.
- Conditions
- Opioid Use Disorder, Pregnancy Related, Substance Use, Drug Abuse
- Trial name
- TOME (NCT06262347)
- Testing
- Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME), Control
- Where
- 6 sites in United States
- Volunteers
- 131 people
- Sponsor
- T. John Winhusen, PhD
Gestational Diabetes Mellitus
Barriers to Adherence to Recommended Follow-up in Women With a History of Gestational Diabetes
The purpose of this study is to find out whether women who have had gestational diabetes mellitus (GDM) will make healthier lifestyle choices, achieve weight goals, and complete postpartum care assessments after receiving two…
- Trial name
- NCT01681147
- Testing
- 2 online nutrition and exercise education classes, Self monitoring of blood glucose levels
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joslin Diabetes Center
Mood, Parents
The Acute Effects of Blueberries on Cognition and Mood in the Postpartum
Blueberries are an excellent source of natural substances (flavonoids) with well-documented health benefits. Previous research has shown that consuming a serving of blueberries can improve mood in children, healthy young adults…
- Conditions
- Mood, Parents, Healthy
- Trial name
- BLUCAMP (NCT06402916)
- Testing
- Blueberry drink
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hypertensive Disorder of Pregnancy
Remote Postpartum Intervention Targeting Movement Behaviors After Hypertensive Disorders of Pregnancy
The purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of a postpartum physical activity intervention after a pregnancy complicated by a Hypertensive Disorder of Pregnancy.
- Trial name
- NCT06019715
- Testing
- Postpartum Remote Physical Activity Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jackie Dziewior
Postnatal Depression, Depression, Postpartum
Randomised Control Trial of a Complex Intervention for Postnatal Depression
The study aims to: 1. Develop a culturally appropriate psychosocial intervention 2. Test feasibility and acceptability of psychosocial intervention in women suffering from postnatal depression.
- Trial name
- NCT01309516
- Testing
- Complex Intervention
- Where
- 2 sites in Pakistan
- Volunteers
- 107 people
- Sponsor
- Pakistan Institute of Living and Learning
Severe Postpartum Depression
A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression
This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the efficacy, safety, and pharmacokinetics of SAGE-547 Injection in adult female participants diagnosed with severe postpartum…
- Trial name
- NCT02614547
- Testing
- SAGE-547
- Where
- 4 sites in United States
- Volunteers
- 21 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Postpartum Hemorrhage, Uterine Atony
Balloon Tamponade Versus Gauze Packing for Postpartum Hemorrhage
Postpartum hemorrhage due to uterine atony is a major cause of maternal morbidity and mortality. This randomized controlled trial aims to compare the efficacy of uterine balloon tamponade and uterine gauze packing in controlling…
- Trial name
- NCT07609589
- Testing
- Uterine Balloon Tamponade, Uterine gauze packing
- Volunteers
- 216 people
- Sponsor
- Khyber Teaching Hospital