Clinical trials: Postprandial
Postprandial Glucose Response
Effect of Degree of Polymerization and Linkage of α-glucans on Post-prandial Glucose Response
The primary research project objective is to investigate whether a maltodextrin with high degree of polymerization (Roquette Glucidex 2) and a dextran with comparable degree of polymerization (Pharmacosmos Dextran 10) have lower…
- Trial name
- NCT05266690
- Testing
- Roquette Glucidex 2, Pharmacosmos Dextran 10, Roquette Glucidex 40
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy
Study of the Effect of Food Intake on the Bioavailability of XC8 10 mg Film-coated Tablets
Primary objective of the study: evaluation of the effect of food intake on the bioavailability of XC8, film-coated tablets, 10 mg after a single oral administration in fed or fasted condition at a dose of 20 mg (two tablets).
- Trial name
- NCT05294250
- Testing
- XC8
- Where
- Russia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Diabetes Mellitus, Type 2
A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects
An open-label, phase II study to assess the acute and chronic effects of empagliflozin (BI 10773)on fasting and postprandial glucose homeostasis in patients with IGT and type 2 diabetes mellitus and assess the acute effects of…
- Trial name
- NCT01248364
- Testing
- BI 10773
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Effect of Changes in Glucose Intake and Sweet Perception on Post Prandial Glycaemia
Sugar-sweetened beverages are the main source of added sugars in most Westernized countries, and for this reason constitute a primary target for sugar reduction by many companies, including Nestlé.
- Trial name
- NCT03613935
- Testing
- Product 1, Product 2, Product 3
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Prediabetic State, Dysglycemia
Mode of Action (MoA) Study of TOTUM-63 in Individuals at Increased Cardio-metabolic Risk
This clinical study aims to investigate the effects of TOTUM-63, a mix of 5 plant extracts, consumed at the daily regimen of three times per day, on cardiometabolic health and gut microbiota profile in overweight-obese…
- Conditions
- Prediabetic State, Dysglycemia, Overweight and Obesity
- Trial name
- NCT05369585
- Testing
- TOTUM-63
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Idiopathic Gastroparesis
A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adult Subjects With Idiopathic Gastroparesis.
The goal of this clinical trial is to evaluate if the study drug CIN-102 (deudomperidone) can help to decrease nausea severity associated with idiopathic gastroparesis severity in adult subjects.
- Trial name
- NCT06899217
- Testing
- CIN-102 Dose 15mg, CIN-102 Dose 10mg
- Where
- 85 sites in United States
- Volunteers
- 416 people
- Sponsor
- CinDome Pharma, Inc.
Diabetes Mellitus, Type 2
Plant-based Ingredient on Post Prandial Glucose in Type II Diabetes
Effects of a plant based ingredient on blood glucose in Type II diabetes patients.
- Trial name
- NCT02256332
- Testing
- Low dose plant based ingredient, High dose plant based ingredient, Reference food format
- Where
- 2 sites in India
- Volunteers
- 24 people
- Sponsor
- Unilever R&D
Postprandial Hyperglycemia
Determination of the GI and II Values of Soft Drink and Soft Drink With Sugardown™
This study was a partly controlled laboratory-based study comparing the glycemic and insulinemic indices of 3 test meals containing soft drink alone or with SUGARDOWN™ (Galactomannan) in overweight adults.
- Trial name
- NCT03374501
- Testing
- Sugardown™, Soft drink
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Therapeutics
Hyperglycemia, Postprandial
Efficacy of Glucosanol™ in Reducing Post-prandial Glucose Levels in Overweight Subjects
Glucosanol had previously been proven to be effective in aiding weight loss and weight loss maintenance. Studies have also shown that Glucosanol (also known as Phaseolamin), was effective in aiding weight loss and also has…
- Trial name
- NCT02930681
- Testing
- Glucosanol 500mg
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Drug-induced Weight Gain
Effect of RDX-002 on Postprandial Triglycerides in Subjects Treated With Olanzapine
This Phase 1b Study RDX-002-22-09 has been planned to evaluate the effect of RDX-002 on postprandial triglycerides and ApoB48 levels in normal healthy subjects treated with the atypical antipsychotic drug, olanzapine.
- Trial name
- NCT05857566
- Testing
- RDX-002 + Olanzipine, Olanzapine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Response Pharmaceuticals
Healthy Subjects
Post-prandial Glucose in Healthy Indian Subjects
The study is designed to determine the extent to which a plant-based ingredient on different food formats affect blood glucose responses in healthy subjects
- Trial name
- NCT01999543
- Testing
- plant-based dietary supplement
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Hyperprolactinemia
A Study on Bioequivalence of Cabergoline Tablets in Human Body
The purpose of this study is to evaluate the bioequivalence of the test formulation and reference formulation of cabergoline tablets in healthy Chinese subjects under fasting and postprandial conditions.
- Trial name
- NCT07008417
- Testing
- Cabergoline tablets test formulation, Cabergoline tablets reference formulation
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Overweight and Obesity
Metabolic Response to Beverages With Various Sweetening Systems Consumed During Meal in Overweight and Obese Subjects
The purpose of this clinical study is to investigate the effect of drinking a sugar-sweetened beverage along with a meal on insulin concentrations and, glucose and lipid metabolism, in overweight and obese subjects, during a…
- Trial name
- AQUAGLU-1 (NCT02932423)
- Testing
- Control product E, Test product A, Test product B
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Danone Global Research & Innovation Center
Gestational Diabetes Mellitus in Pregnancy
Meal Tolerance Trial in Pregnant Women Diagnosed With Gestational Diabetes Mellitus.
This study is initiated to investigate the effect of a nutritional product on the 3-hr postprandial glucose response compared to a control standard breakfast at baseline and after 4 weeks of intervention.
- Trial name
- GDM-MTT (NCT02225951)
- Testing
- Nutritional product, Standard breakfast according to ADA recommendations
- Where
- Singapore
- Volunteers
- 3 people
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Healthy Men
Study to Evaluate the Effects of Psyllium on Blood Glucose
This is an open label, single use, randomized, 4-period cross-over study. In each period, subjects will receive one of 4 test combinations.
- Trial name
- NCT00888602
- Testing
- 3.4 g psyllium, 6.8 g psyllium, Meal
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Glycemic Control
Glycemic Response in Adults With Type 2 Diabetes
This is a randomized, controlled, crossover study to compare the effects of two treatments on postprandial glucose in adults with type 2 diabetes.
- Trial name
- NCT05166200
- Testing
- Experimental Formula, Test Meal
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Abbott Nutrition
Dyslipidemia, Hypercholesterolemia
A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1)
This study will evaluate whether fasting/postprandial serum ApoB-48 levels are increased in diabetic participants compared to nondiabetic participants with the same range of serum LDL-C levels, and whether ApoB-48 levels can be…
- Trial name
- NCT01333436
- Testing
- Test Meal
- Where
- South Korea
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Diabetes Mellitus
Prevention of Postprandial Hyperglycemia by Acarbose May be a Promising Therapeutic Strategy for Reducing the Increased Risk for Cardiovascular Disease
The use of acarbose in impaired glucose tolerance (IGT) and type 2 diabetic subjects has been associated with a significant reduction of cardiovascular events.
- Trial name
- ABDOMEN (NCT01167231)
- Testing
- Acarbose (Glucobay, BAYG5421)
- Where
- Poland
- Volunteers
- 3,310 people
- Sponsor
- Bayer
Blood Glucose, Postprandial
Effect of Escalating Doses of a Novel Viscous Polysaccharide on Postprandial Glycemia
To determine palatability and extent to which escalating doses of a novel highly viscous polysaccharide [NVP] reduces postprandial glycemia when added to a liquid and a solid meal.
- Trial name
- NCT00801814
- Testing
- PolyGlycopleX (PGX), PolyGlycopleX (PG), PolyGlycopleX
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Diabetes Mellitus
BIOD-531 vs. Humalog Mix 75/25 vs. Humulin R U-500 Post-Meal Glucose Control in Patients With Severe Insulin Resistance
The study is designed to compare meal time glucose control associated with BIOD-531, a rapidly absorbed concentrated insulin to that associated with Humalog Mix 75/25 and Humulin R U-500 in patients with diabetes and severe…
- Trial name
- NCT02324309
- Testing
- BIOD-531, Humalog Mix 75/25, Humulin R U-500
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Biodel