Clinical trials: Postprandial
Functional Dyspepsia
DLBS2411 Treatment For Functional Dyspepsia
This is a 2-arm, prospective, double-blind, randomized and placebo-controlled study using DLBS2411 at a dose of 250 mg twice daily (before morning and evening meals), for a 4-week course of therapy, for the treatment of patients…
- Trial name
- NCT05248802
- Testing
- DLBS2411
- Where
- 8 sites in Indonesia
- Volunteers
- 106 people
- Sponsor
- Dexa Medica Group
Diabetes Mellitus, Type 2
A Clinical Study to Assess the Effect of Vildagliptin on Postprandial Lipid Parameters in Patients With Type 2 Diabetes
This study was not conducted in the United States. Many people with type 2 diabetes also have high cholesterol levels. The purpose of this study was to evaluate the effects of vildagliptin, an unapproved drug, on blood lipid…
- Trial name
- NCT00099957
- Testing
- vildagliptin
- Where
- Switzerland
- Volunteers
- 38 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus, Type 2
Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients
The purpose of this phase IV clinical trial is to investigate the effect of Insulin glargine + metformin treatment vs. sulfonylurea + metformin treatment vs. DPP-4 + metformin treatment vs.
- Trial name
- NCT01206712
- Where
- Germany
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- ikfe-CRO GmbH
Type 2 Diabetes
A Study to Evaluate P-Glucose, Safety and Tolerability After Oral Single Dosing of AZD6370 in Type 2 Diabetic Patients
The purpose of this study is to assess the effect of AZD6370 on blood sugar and to study safety and tolerability in patients with type 2 diabetes.
- Trial name
- NCT00690287
- Testing
- AZD6370
- Where
- 3 sites in Sweden
- Volunteers
- 24 people
- Sponsor
- AstraZeneca
Healthy Volunteers, Recovery
Effects of Carnipure® Tartrate on Postprandial Endothelial Function and Recovery
Investigation of 4 weeks supplementation with Carnipure® tartrate on endothelial function and parameters of recovery after physical exertion.
- Conditions
- Healthy Volunteers, Recovery, Endothelial Function
- Trial name
- NCT02635594
- Testing
- L-Carnitine
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lonza Ltd.
Diabetes Mellitus, Type 2
Acute Study of Effect of Ultrasound Vagus Nerve Stimulation on Glycemia
This is an early feasibility study to evaluate the proof of concept of modulation of glycemia by non-invasive ultrasound vagus nerve stimulation.
- Trial name
- NCT04094649
- Testing
- Ultrasound Vagus Nerve Stimulation (DECIMA)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Aucta Technologies, Inc.
Diabetes
Evaluation of the Effects of Heating or Massaging or Vibrating at the Vicinity of the Insulin Delivery Site
The aim of this study is to test the pharmacodynamics of insulin analogs and their dependence on external and physiological alterations.
- Trial name
- NCT00767741
- Testing
- with heat and massage
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Insuline Medical Ltd.
Reduction of Post-prandial Glycaemic Response
Effects of Added D-fagomine on Glycaemic Responses to Sucrose
The purpose of this study is to determine whether D-fagomine affects glycaemic responses to sucrose (commercial white sugar)and quantify the response
- Trial name
- NCT01811303
- Testing
- D-fagomine
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bioglane
Multiple Sclerosis, Muscle Spasticity
Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.
This study is being conducted to compare the impact of somnolence (sleepiness) on cognition (awareness) as well as the safety and effectiveness of tizanidine hydrochloride capsules versus Zanaflex® (tizanidine hydrochloride…
- Conditions
- Multiple Sclerosis, Muscle Spasticity, Spinal Cord Injury, Stroke
- Trial name
- NCT00047580
- Testing
- tizanidine hydrochloride capsule
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- Elan Pharmaceuticals
Healthy
Identification of Biometric Marker(s) Capable of Detecting Early Prediabetes: Clinical Trial 1
The proposed clinical trial is a controlled study of n=24 healthy adult individuals tested in both the Meal-Induced Insulin Sensitization (MIS) state and, following atropine blockade, Absence of Meal-Induced Insulin Sensitization…
- Trial name
- NCT04625088
- Testing
- Standardized liquid test meal, Atropine + Standardized liquid test meal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- SciMar Ltd.
Healthy
Evaluation of the Pharmacokinetic Interaction Between Candesartan and Felodipine After Ingestion of a Specific Meal
The purpose of this study is to evaluate the pharmacokinetic interaction of test formulations of candesartan and felodipine in a combination package comparing with the fasting intake of commercial formulations of both Atacand ®…
- Trial name
- NCT00905333
- Testing
- Candesartan (test), Felodipine (test), Candesartan Cilexetil
- Where
- 2 sites in Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Functional Dyspepsia
Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia
The study is conducted in patients with functional dyspepsia or chronic gastritis. The purpose of this study is to: assess whether the dose of Itopride Hydrochloride 150 mg extended release tablets, taken once daily has a similar…
- Trial name
- NCT06217393
- Testing
- Itopride Hydrochloride 150 mg extended release tablets, Itopride Hydrochloride 50 mg film coated tablets
- Where
- 19 sites in Armenia, Malaysia and 3 more
- Volunteers
- 564 people
- Sponsor
- Abbott
Type 2 Diabetes
Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone
This study will assess the safety and efficacy of adding nateglinide to treatment with basal insulin glargine, metformin and/or thiazolidinedione (pioglitazone or rosiglitazone), for patients with type 2 diabetes who are not…
- Trial name
- NCT00402909
- Testing
- Nateglinide
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Novartis Pharmaceuticals
Amino Acid Plasma Profile
Dairy and Plant Amino Acid Uptake. An Explorative Study
To optimize the environmental sustainability, a protein transition to more plant-based protein sources is required. However, the protein quality of plant-based sources is lower than that of the dairy proteins casein and whey…
- Trial name
- DaPa (NCT05813769)
- Testing
- Dairy protein, Plant protein
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Healthy
Effect of Tea Extract on Post Prandial Blood Glucose
This study is designed as a randomized, single blind (data evaluation), placebo controlled, full cross-over study and conducted in 166 (including 10% drop out) males and females, aged ≥ 18 and ≤ 65 and waist circumference of >80…
- Trial name
- NCT03066323
- Testing
- Rice with tea extract, Rice without tea extract
- Where
- Ireland
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Diabetes Mellitus Type 2
Effect of Linagliptin in Comparison With Glimepiride as Add on to Metformin on Postprandial Beta Cell Function, Postprandial Metabolism and Oxidative Stress in Patients With Type 2 Diabetes Mellitus
The goal of this mechanistic study is to investigate the effect of Linagliptin in comparison to Glimepiride as add on therapy on several parameters characterizing postprandial metabolism and oxidative stress in type 2 diabetic…
- Trial name
- NCT01547104
- Testing
- Linagliptin, Glimepiride
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Marcus Borchert
Diabetes Mellitus, Upper Respiratory Infection
Effects of URI on Diabetic Subjects Utilizing Technosphere Insulin After a Meal Challenge
Effect of upper respiratory infection (URI) on diabetic subjects with a meal challenge
- Trial name
- NCT00642681
- Testing
- Technosphere Insulin
- Where
- 24 sites in United States, Canada and 1 more
- Volunteers
- 20 people
- Sponsor
- Mannkind Corporation
Postprandial Hyperglycemia, Metabolic Syndrome
Effects of a Carbonated Water Enriched With Amino Acids and Chromium Picolinate (Good Idea®) on Glucose Homeostasis.
It has previously been shown in healthy subjects, that a carbonated water containing a mix of amino acids and chromium picolinate can decrease postprandial blood glucose.
- Conditions
- Postprandial Hyperglycemia, Metabolic Syndrome, Type 2 Diabetes Mellitus
- Trial name
- NCT03552315
- Testing
- Carbonated water with amino acids and chromium
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- DoubleGood AB
Healthy Volunteers
A Study in Healthy Participants Investigating Biomarkers After Exposure to Heparin When Heparin is Administered in the Fasted State or After a High-fat Meal. Heparin, a Registered Drug, is an Anticoagulant (Blood Thinner) That Prevents the Formation of Blood Clots.
In this study biomarkers in the blood after exposure to heparin in the fasted state or after a high-fat meal will be investigated.
- Trial name
- NCT05178550
- Testing
- Heparin
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy Subjects
Post-prandial Glucose in Healthy Subjects
The study is designed to determine the extent to which foods containing different levels of plant-based ingredients affect blood glucose responses in healthy subjects.
- Trial name
- NCT01955447
- Testing
- no added plant-based ingredients to starchy meal, Low level plant-based ingredients added to starchy meal, Medium level plant-based ingredients added to starchy meal
- Where
- India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Unilever R&D