Clinical trials: Postprandial
Postprandial Hyperglycemia, Type2 Diabetes
The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans
The main objective of the current study is to investigate whether consumption of soluble fibers (isomaltodextrin [IMD], partially digestible maltodextrin) and RS4 starch will lower postprandial glycemia as well as postprandial…
- Conditions
- Postprandial Hyperglycemia, Type2 Diabetes, Blood Sugar; High
- Trial name
- NCT05349916
- Testing
- Control, Isomaltodextrin Low Dose, Isomaltodextrin High Dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue University
Polycystic Ovary Syndrome
Effect of Meal Composition on Postprandial Testosterone Concentration in Women With Polycystic Ovary Syndrome
The primary objective is to determine if meals of different fat and fiber content affect postprandial plasma testosterone concentration in women with polycystic ovary syndrome.
- Trial name
- NCT00455338
- Testing
- Meal Composition
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Overweight and Obesity
Evaluation of Libramed in Obesity Treatment
Randomized, double-blind, placebo-controlled study aimed at evaluating the effects of a 3-months treatment with Policaptil Gel Retard on postprandial incretin hormones release and satiety in obese women
- Trial name
- ELOT (NCT03537235)
- Testing
- Libramed
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Aboca Spa Societa' Agricola
Advanced Malignant Solid Tumors
Bioequivalency Study of CM082 Tablet in Healthy Volunteers
The main objective of this study is to evaluate the bioequivalency of two preparations of CM082 tablet in Chinese healthy volunteers.
- Trial name
- NCT04328506
- Testing
- CM082 tablet (test product), CM082 tablet (reference product)
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- AnewPharma
Hypertriglyceridemia
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
The primary objective of the study is to determine the effect of MAR001 as compared to placebo on levels of the triglycerides (TG) in the postprandial state in adults with elevated TG.
- Trial name
- NCT07199309
- Testing
- MAR001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marea Therapeutics
Diabetes Mellitus, Type 2
Post Prandial Glucose (PPG) Study of Empagliflozin in Japanese Patients With Type 2 Diabetes Mellitus
To evaluate the efficacy of empagliflozin administered orally once daily in postprandial glucose and 24-hour glycaemic variability compared to placebo given for 4 weeks as mono-therapy in Japanese patients with type 2 diabetes…
- Trial name
- NCT01947855
- Testing
- Empagliflozin
- Where
- 2 sites in Japan
- Volunteers
- 60 people
- Sponsor
- Boehringer Ingelheim
Hyperlipidemia
Effect of Different Types of Carbohydrates Consumed After Exercise on Blood Fat Levels
The increase in fat (i.e. triglyceride) in the blood after a meal is a well-established risk factor for heart disease (Nordestgaard et al. 2007).
- Trial name
- NCT02012855
- Testing
- Exercise, Diet (meal type)
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Liver Fibrosis/NASH
Stimulating Fat Tissue Storage With Niacin to Reduce Fat Accumulation in the Liver.
Metabolic dysfunction-associated steatotic liver disease (MASLD) (aka non-alcoholic fatty liver disease), commonly occurring in individuals with obesity and type 2 diabetes can lead to liver inflammation/ fibrosis.
- Conditions
- Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Liver Fibrosis/NASH, Non-Alcoholic Steato-Hepatitis (NASH)
- Trial name
- AGL13 (NCT06843148)
- Testing
- Niacin (250mg)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Université de Sherbrooke
Obesity, Skeletal Muscle
Anti-Inflammatory Milk Matrix
Obesity is pro-inflammatory, impairs metabolism, and physically limiting. Specifically, muscle in obese persons does not synthesize proteins normally. This further increases metabolic and physical dysfunction.
- Conditions
- Obesity, Skeletal Muscle, Inflammation
- Trial name
- AIMM (NCT04216004)
- Testing
- Controlled-Feeding Intervention, Non-dairy beverage, Full-fat milk
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Inflammatory Response, Inflammation
Fat Quality and Postprandial Inflammation
This aim of this randomized controlled postprandial study is to compare the effects of four different far sources (butter, coconut, corn oil and flax seed oil) on postprandial inflammation and metabolic response.
- Trial name
- PI:fat (NCT05674708)
- Testing
- Fat intake
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Hyperglycemia, Diabetes, and Obesity
Effects of Resistant Starch in a Beverage on Post-prandial Glycemic and Insulinemic Responses
Hypothesis: A beverage with a resistant starch will blunt and sustain the post-prandial rise in blood glucose and insulin concentrations compared to beverage with maltodextrin (an easily digested carbohydrate).
- Trial name
- NCT02161250
- Testing
- Resistant Starch, Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Nitric Oxide, Vascular Function
Nutritional Supplements and Nitric Oxide Bioactivity
Obese people have a disturbed postprandial metabolism and thereby a decreased postprandial vascular function. Nitric oxide plays an important role in the postprandial vascular function.
- Conditions
- Nitric Oxide, Vascular Function, L-Arginine, Nitrate / Nitrite
- Trial name
- NCT03625596
- Testing
- L-Arginine, Nitrate / Nitrite
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Nonalcoholic Fatty Liver Disease (NAFLD)
Postprandial Lipotoxicity and Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is mainly considered a nutrition-related disease and life-style/diet interventions showed some promising results.
- Trial name
- LITONAS (NCT03836443)
- Testing
- western diet" meal
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
Effect of Changes in Glucose Intake and Sweet Perception on Post Prandial Glycaemia
Sugar-sweetened beverages are the main source of added sugars in most Westernized countries, and for this reason constitute a primary target for sugar reduction by many companies, including Nestlé.
- Trial name
- NCT03613935
- Testing
- Product 1, Product 2, Product 3
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Osteoporosis
The Postprandial Calcium Absorption of a Milk Derived Calcium Permeate - RENEW Acute Study
This is a randomized controlled cross-over meal study with the overall aim to investigate the postprandial calcium absorption from calcium permeate compared with calcium carbonate.
- Trial name
- NCT04550078
- Testing
- Calcium Carbonate, Calcium Permeate
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Inge Tetens
Diabetes, Gestational, Pregnancy Complications
Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes
Pregnant women aged 18-45 with gestational diabetes (GDM) will take part in this study. We want to see how two different insulin treatments affect their blood sugar after they eat.
- Conditions
- Diabetes, Gestational, Pregnancy Complications, Glucose Metabolism Disorders, Glucose Intolerance During Pregnancy
- Trial name
- INHALE-GDM (NCT06535789)
- Testing
- Inhaled Technosphere Insulin
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Jaeb Center for Health Research
Diabetes Type 2, Obesity
Does Green Tea Affect Postprandial Glucose, Insulin and Satiety in Healthy Subjects
Green tea consumption could lower the risk of type II diabetes, as suggested by epidemiological studies. There is also evidence from intervention studies that green tea can decrease blood glucose levels and contribute to weight…
- Trial name
- NCT01086189
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Demonstrate That the Postprandial Glucose Response of FiberSMART is Consistent With the Response Expected From a Dietary Fiber
Effect of Tapioca-based FiberSMART® Compared to a Glucose Challenge or Water Control on Postprandial Glycemia in Healthy Subjects: An Acute Randomized Controlled Trial
The goal of this clinical trial is to learn whether a novel tapioca-based soluble fiber, FiberSMART®, affects blood glucose levels after consumption in healthy adult volunteers.
- Trial name
- NCT07075822
- Testing
- 20g of FiberSMART®, 20g of Dextose, Water Control
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- INQUIS Clinical Research
Diabetes, Diabetes Mellitus, Type 2
Glycemic Control of Biphasic Insulin Aspart 30 in Type 2 Diabetes
This this trial is conducted in Europe. The aim of this trial is to compare glycaemic control of biphasic insulin aspart 30 (BIAsp 30) alone or combined with insulin aspart(IAsp) in patients previously treated with conventional…
- Trial name
- NCT01697631
- Testing
- biphasic insulin aspart 30, insulin aspart
- Where
- 12 sites in Poland
- Volunteers
- 131 people
- Sponsor
- Novo Nordisk A/S
Blood Flow
The Role of GIP and GLP-2 in Postprandial Splanchnic Blood Flow Distribution and Metabolism
This project will describe the mechanisms of action and the relative contributions of GIP and GLP-2 to changes in gastrointestinal blood flow induced by oral glucose, exogenous GIP and GLP-2 infusions, and endogenous GIP and…
- Trial name
- GA-17 (NCT05391581)
- Testing
- GIPR antagonist / study tool, GLP-2R antagonist / study tool
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
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