Clinical trials: Postprandial
Diabetes
Effects of an Amino Acid and Chromium-picolinate Containing Drink on Glucose Metabolism on Healthy Subjects
It has previously been shown in healthy overweight subjects, that table water including a defined amount of amino acids and chromium can decrease the postprandial glucose.
- Trial name
- NCT02487680
- Testing
- Amino Acids and chromium-picolinate containing drink
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DoubleGood AB
Glycaemia
Glycaemic Responses to Carbohydrate-rich Meals (GlyCarb)
Carbohydrate-rich foods such as potatoes, bread, rice, pasta, breakfast cereals, biscuits and other snacks are a major component of the human diet.
- Trial name
- GlyCarb (NCT05317429)
- Testing
- A meal delivering 75 g of carbohydrate
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Healthy
Conditioning Effect of Previous Symptoms on the Responses to Meal Ingestion
Meal ingestion induces sensations that are influenced by a series of conditioning factors. Aim: to determine the conditioning effect of previous digestive symptoms to a standardized probe meal.
- Trial name
- NCT04938934
- Testing
- Lipids infusion
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Obesity, Pre Diabetes
Personalized Nutrition Based on the Glycemic Response: Effect of Diet and Intestinal Microbiota
This study will investigate whether changes in the intestinal microbiota generated through a nutritional strategy based on functional foods, modifies postprandial glycemic responses in subjects with prediabetes and obesity, which…
- Trial name
- NCT05230342
- Testing
- A package containing a mix of functional foods
- Where
- 2 sites in Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Type 1 Diabetes
Use of Mobile-based Technologies to Improve Diabetes Self-management and Postprandial Glucose Control
The project involve evaluation of a web-based nutrition education program and pilot-testing of a new smartphone app for real-time data logging to identify factors causing glycemic variability.
- Trial name
- NCT02556398
- Testing
- Sugar Sleuth
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Joslin Diabetes Center
Time Restricted Feeding
Prolonged Overnight Fast, Energy Metabolism and Skeletal Muscle Anabolic Sensitivity
Recent research shows that timing of nutritional intake and daily periods of fasting may have important health effects. In humans, limiting daily food intake to a narrow window (typically ~8 hours) can bring about some beneficial…
- Trial name
- NCT05420181
- Testing
- Short 10hr fast, Long 16h fast
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Postprandial Lipemia, Type 2 Diabetes
Differential Effects of Milk Proteins on Postprandial Lipemia in Response to a Fat-Rich Meal in Type 2 Diabetes
Enhanced and prolonged postprandial triglyceride responses involve increased cardiovascular risk in type 2 diabetes. It has been demonstrated that dietary fat and carbohydrates profoundly influence postprandial…
- Trial name
- NCT00819975
- Testing
- Casein, Whey Isolate, Whey Hydrolysate
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Aarhus University Hospital
Postprandial Hyperglycemia, Overweight and Obesity
A Study of Biochemical Response to Alternative Proteins
The overall objective of this research is to determine the digestive faith and health impact of protein and fiber rich foods in different food matrices in type 2 diabetes risk population.
- Conditions
- Postprandial Hyperglycemia, Overweight and Obesity, Type2diabetes
- Trial name
- COBRA (NCT06253728)
- Testing
- High fiber and protein meal, Control
- Where
- Finland
- Volunteers
- 24 people
- Sponsor
- University of Eastern Finland
Blood Flow
The Role of GIP and GLP-2 in Postprandial Splanchnic Blood Flow Distribution and Metabolism
This project will describe the mechanisms of action and the relative contributions of GIP and GLP-2 to changes in gastrointestinal blood flow induced by oral glucose, exogenous GIP and GLP-2 infusions, and endogenous GIP and…
- Trial name
- GA-17 (NCT05391581)
- Testing
- GIPR antagonist / study tool, GLP-2R antagonist / study tool
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Gestational Diabetes, Pregnancy Complications
Timing of Ambulation and Infant Birth Weight in Gestational Diabetes
This is a randomized controlled trial to assess the effect of routine exercise counseling compared to the recommendation for postprandial ambulation on infant birthweight among pregnant people with gestational diabetes mellitus.
- Conditions
- Gestational Diabetes, Pregnancy Complications, Pregnancy in Diabetic, Fetal Macrosomia
- Trial name
- NCT06157684
- Testing
- Postprandial ambulation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Post-Prandial Hyperglycemia, Post-Prandial Hypoglycemia
Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop Therapy
The study will be conducted in two phases; an in-patient meal study phase (Phase I) and an outpatient home study (Phase II). The two phase study design is chosen to enhance safety by testing the Afrezza Closed-Loop (CL) system in…
- Trial name
- NCT03234491
- Testing
- DiAS, Afrezza low dose, Afrezza high dose
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Type 2 Diabetes, Atherosclerosis
The Copenhagen Insulin and Metformin Therapy Trial
Type 2 Diabetes Mellitus patients (T2DM) have an increased mortality rate due to macrovascular disease. The primary objective of the study is to evaluate the effect of an 18-month treatment with metformin versus placebo in…
- Conditions
- Type 2 Diabetes, Atherosclerosis, Arteriosclerosis
- Trial name
- CIMT (NCT00657943)
- Testing
- metformin, insulin detemir, insulin aspart + insulin aspart protamin
- Where
- 9 sites in Denmark
- Volunteers
- 415 people
- Sponsor
- Steno Diabetes Center Copenhagen
Abdominal Obesity, Postprandial Lipemia
Alternating Energy Intake and Blood Fat Content After a Meal
Increasing evidence suggests that meal timing affects metabolic health. For example, intermittent fasting (IF) may have positive effects on plasma glucose and lipid levels, insulin sensitivity, and blood pressure.
- Conditions
- Abdominal Obesity, Postprandial Lipemia, Lipid Metabolism, Glucose Metabolism
- Trial name
- NCT04894526
- Testing
- Alternating Energy Intake, Regular Energy Intake
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Gastroparesis
Indiana University Gastric Electrical Stimulation Registry
The purpose of this study is to develop a clinical registry in patients with Gastric Electrical Stimulation (GES) therapy for gastroparesis to support future gastrointestinal therapies, medical procedures and diagnostics.
- Trial name
- NCT05047289
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Indiana University
Healthy
Pharmacokinetics Study of Zolpidem Hemitartarate Orodispersible Tablet 3.5 mg Formulation
The purpose of this study is to evaluate the pharmacokinetics of the new formulation of zolpidem hemitartarate orodispersible tablet 3.5 mg in male and female healthy volunteers.
- Trial name
- NCT02817750
- Testing
- zolpidem hemitartarate tablet 3.5 mg (fasting + post-prandial), zolpidem hemitartarate tablet 3.5 mg (post-prandial + fasting)
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Diabetes, Heart Diseases
PREDICT 2: Personalized Responses to Dietary Composition Trial 2
Foods in the human diet can affect the development of diseases over time, such as diabetes or heart disease. This is because the amount and types of foods in the diet eat can affect a person's weight, and because different foods…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT03983733
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Overweight, Obesity
Diet, Insulin Sensitivity, and Postprandial Metabolism
This randomized, controlled trial aims to elucidate the mechanisms by which a plant-based dietary intervention causes weight loss.
- Conditions
- Overweight, Obesity, Insulin Resistance
- Trial name
- TEF (NCT02939638)
- Testing
- Plant-based diet, Control Diet
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Physicians Committee for Responsible Medicine
Normal Weight, Overweight
Roasted Pulse Snacks, Post-prandial Food Intake, Appetite, and Glycemia
An investigation on the effects of roasted pulse snacks on post-prandial glycemic and satiety response in healthy young adults.
- Conditions
- Normal Weight, Overweight, Normoglycemic
- Trial name
- NCT03223935
- Testing
- Corn nuts, Chickpeas, Yellow peas
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Diabetes Mellitus, Ketosis
The Effect of a Ketone Drink on Liver Glucose Production in People With Type 2 Diabetes
What is the effect of a ketone drink on liver glucose production, and postprandial glycemia, in people with type 2 diabetes.
- Trial name
- KES2 (NCT05518448)
- Testing
- Ketone - beta-hydroxybutyrate (β-OHB)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Exeter
Glucose, Insulin
Does Passive Movement Increase Glucose Uptake Into Muscle?
This study aims to examine the blood sugar response after a meal, and how three different movement protocols may impact the blood sugar level. Participants will visit the lab on three different occasions.
- Conditions
- Glucose, Insulin, Blood Flow Restriction Therapy, Blood Flow Velocity
- Trial name
- NCT06704126
- Testing
- Passive movement, Passive movement with blood flow restriction
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Lancaster University
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