Clinical trials: Postprandial
Endothelial Dysfunction, Type 2 Diabetes Mellitus
Effects of Benfotiamine and AGE on Endothelial Function in People With Diabetes
The purpose of the study is to determine whether there are differences in postprandial endothelial function following a high-AGE(Advanced Glycation End-products) meal vs. a low-AGE meal.
- Trial name
- AGE-Benfo (NCT00437008)
- Testing
- Benfotiamine 1050mg, 3 days, high-AGE vs. low-AGE meal
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- Ruhr University of Bochum
Type 2 Diabetes, Obesity
Effect of Discontinuation of Sugar Sweetened Beverages
Purpose The purpose of this study is to investigate the effects of discontinuation of sugar sweetened beverages on hemoglobin A1c (HbA1c) and plasma fasting and post-prandial blood glucose in a population with type 2 diabetes.
- Trial name
- NCT00585897
- Testing
- discontinuation of sugar sweetened beverages
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Type 1 Diabetes
Extended Bolus for Meals in a Closed-loop System
This study aims to evaluate whether the use of an extended bolus will improve glucose control with high-fat high protein meals using a closed-loop system.
- Trial name
- NCT05454891
- Testing
- Tandem t:slim X2 insulin pump: Extended bolus of insulin then standard bolus of insulin, Tandem t:slim X2 insulin pump: Standard bolus of insulin then extended bolus of insulin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Type 2 Diabetes Mellitus
Lipid, Glycemic, and Insulin Responses to Meals Rich in Different Fatty Acids
A meal rich in very-long chain omega-3 fatty acids or oleic acid may lower postprandial insulin levels in comparison to a meal rich in linoleic acid or palmitic acid.
- Trial name
- NCT00479791
- Testing
- Test meals rich in different fatty acids
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Type 2 Diabetes
Effect of Bile Acid Sequestration on Postprandial GLP-1 Secretion, Glucose Homeostasis and Gut Microbiota
Accumulating evidence suggests that bile acids and bacteria in our intestines may constitute essential components in the complex mechanisms regulating gut hormone secretion and glucose homeostasis.
- Trial name
- NCT02061124
- Testing
- Sevelamer 1600 mg TID for 7 days
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Healthy
Emulsion Lipid Digestion & Satiety Study - Effect of Physical State and Acid Stability
The purpose of this study is to compare the changes in blood lipids and feelings of satiety after consumption of acid stable or acid unstable oil-in-water emulsions in which the droplets are in either the liquid or partially…
- Trial name
- NCT03990246
- Testing
- Acid stable emulsion with solid droplets, Acid stable emulsion with liquid droplets, Acid unstable emulsion with solid droplets
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Cardiovascular Diseases, Metabolic Syndrome
Effects of Canola Oil and Coconut Oil on Postprandial Metabolism in Older Adults With Increased Cardiometabolic Risk
The aim of this study is to investigate the postprandial effects of fat content and fatty acid composition of mixed meals on parameters associated with cardiometabolic diseases.
- Trial name
- NCT05208346
- Testing
- Mixed meals
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Bonn
Cardiovascular Risk Factor
The Acute Effects of Meals Rich in Saturated or Unsaturated Fatty Acids on Postprandial Lipaemia in Healthy Men
Current dietary recommendations suggest that lowering intake of saturated fats or replacing it with unsaturated fats will decrease the risk of developing cardiovascular disease.
- Trial name
- CocoHeart (NCT05264233)
- Testing
- Coconut oil, Butter, Vegetable oil
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hunger
Eating Disinhibition and Vagal Tone and the Postprandial Response to Glycaemic Load
Reducing the glycaemic load (GL) of the diet may benefit appetite control but its utility is complicated by psychological influences on eating.
- Trial name
- NCT02827318
- Testing
- Isomaltulose, Glucose, Sweetened water
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Swansea University
Healthy, Adult
Understanding Effects of Calcium on the Gut-Bone Axis
The study team is inviting 13 healthy people to complete a study to explore how calcium affects hormones and bones after eating. Participants will be asked to complete two study visits within eight weeks.
- Conditions
- Healthy, Adult, Calcium, Bone Resorption
- Trial name
- NCT06383117
- Testing
- Calcium carbonate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Digestive Health, Gastrointestinal Health
Microbial Enzyme Impact on Postprandial Nutrient Levels and Gastrointestinal Symptoms in Healthy Adults
The primary objective of this study is to investigate the acute effects of a microbial multi-enzyme mixture ("BC-006") on postprandial nutrient levels in healthy, middle-aged to older adults during a mixed meal tolerance test.
- Trial name
- BIO-3003 (NCT05211440)
- Testing
- BC-006 + Meal
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Hyperglycemia, Cardiovascular Disease
Green Tea Confections For Managing Postprandial Hyperglycemia-Induced Vascular Endothelial Dysfunction
The objective of this study is to formulate and validate a green tea confection (i.e. "gummy" candy) as a strategy to attenuate postprandial hyperglycemia-induced impairments in vascular function.
- Trial name
- NCT01857258
- Testing
- Green Tea Concentrate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy, Obesity
Validation of the Quark RMR Calorimeter (Cosmed) Versus Deltatrac II (GE Health Care Clinical Systems)
Measurement of energy expenditure at rest (12 hours fasting) and in dynamic phase after a meal (600kcal) to compare the results of the two calorimeters in standardized conditions for the validation of quark RMR versus Deltatrac II
- Trial name
- Protocol Quark (NCT00848471)
- Testing
- Quark RMR, Deltatrac II
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Metabolic Diseases
Intensity Training and Cardiovascular Health in Colombian Adults
Several studies have shown relationship between exercise intensity and improvement cardiometabolic health. It has been suggested that high intensity interval training and also moderate training generate positive effects on…
- Trial name
- HIIT-Heart (NCT02738385)
- Testing
- High Intensity Interval Training, Moderate Intensity Interval Training
- Where
- Colombia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Pregnancy
The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy
This study plans to learn more about how triglyceride levels in pregnancy affect newborn fat mass. Obesity in pregnancy, in the absence of gestational diabetes, is now the most common cause of large-for-gestational-age infants…
- Trial name
- NCT04394806
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cardiovascular Risk Factor, Cardiovascular Diseases
Effects of Breaking up Prolonged Sitting on Postprandial Cardiometabolic Disease Risk Markers in South Asian Adults
The purpose of this study is to examine whether breaking up prolonged sitting with short regular bouts of walking can reduce blood sugar and cholesterol levels after eating, which are risk markers for Type 2 diabetes and heart…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Diabetes, Physical Activity
- Trial name
- NCT03898206
- Testing
- Breaking up sitting with walking breaks (INT-SIT), Prolonged sitting (SIT)
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Inflammation
The Effects of Antioxidants in Blueberry Powder on Inflammation Induced by a Single High Fat Meal.
The goal of the study is to find out whether a high fat meal increases blood lipids and causes monocyte (white blood cell) activation, and whether blueberry intake at the same meal lessens monocyte activation in healthy people.
- Trial name
- FL89 (NCT01594008)
- Testing
- Breakfast meal with 2 serving equivalents of blueberries, Breakfast meal with 4 serving equivalents of blueberries
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Healthy
Effect of Previous Diet
Meal ingestion induces digestive responses associated to homeostatic and hedonic sensations. The responses to meal ingestion are modulated by conditioning factors.
- Trial name
- NCT03783221
- Testing
- High-fat diet, High-residue diet
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Nutrition, Healthy
Effects of the Consumption of SEAweed Biomass Versus PROtein Isolates on Postprandial Satiety and Metabolism
There is a need to identify alternative sources of protein that can be introduced into diets to effectively meet the protein requirements of the population. Seaweed presents a potential source of sustainable, alternative protein.
- Trial name
- SEAPRO (NCT05765448)
- Testing
- Soy control, Intervention (Laver/nori (Porphyra umbillicus) macroalgae whole biomass), Intervention (Laver/nori macroalgae (Porphyra umbillicus) protein isolates)
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Nutrition
Postprandial Responses to Typical UK Meal Nutrient Profiles
The aim of the current study is to investigate the postprandial metabolic response to typically consumed fat and carbohydrate doses in single meals.
- Trial name
- Pre-PREDICT (NCT03531398)
- Testing
- Metabolic test meal challenge
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- King's College London
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