Clinical trials: Postprandial
Prediabetic State
Restoring 24-hour Substrate Rhythmicity to Improve Glycemic Control by Timing of Lifestyle Factors
Exercise is well-known to improve skeletal muscle energy metabolism and is an established intervention to improve muscle insulin sensitivity and to counter the development of type 2 diabetes (T2D).
- Trial name
- TIMED (NCT05123963)
- Testing
- High-intensity interval training
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke
Prediabetes, Hyperglycemia
Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - Main Study
Sweetch is a personalized mobile-health platform coaching system (mobile phone app) designed to promote adherence to physical activity guidelines for people with prediabetes.
- Conditions
- Prediabetes, Hyperglycemia, Postprandial Hyperglycemia, Impaired Glucose Tolerance
- Trial name
- NCT03315663
- Testing
- Sweetch App & DBWS, Sweetch App Alone
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Atherosclerosis, Cardiovascular Diseases
Postprandial Lipoproteins and Atherosclerosis
To determine whether postprandial lipoproteins were associated with atherosclerosis, and if so, whether the association was statistically independent of that between fasting lipoproteins and atherosclerosis.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Carotid Artery Diseases
- Trial name
- NCT00005263
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Columbia University
Postprandial Glycemic Responses
Glycemic Responses of an Innovative Oat Porridge
The aim of this study is to investigate whether enzymatic modification of starch in a food product using amylomaltase induces a lower glycemic response in healthy subjects compared to its unmodified counterpart.
- Trial name
- GREAT (NCT05537649)
- Testing
- Oatmeal porridge
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cardiovascular Diseases
Lipid Challenge in Adults
Participants in this study will have one visit to the Emory University Hospital Clinical Research Unit. Participants will consume, over 5 minutes, a single standardized fat challenge (100 grams), using a commercially available…
- Trial name
- NCT03948295
- Testing
- Lipid Challenge
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Emory University
Energy Expenditure, Metabolic Syndrome
The Impact of Daily Intake of Short-chain Fatty Acids on Cardiometabolic Risk Factors in Individuals at Risk for Metabolic Syndrome
During this study, the effect of short-chain fatty acids on blood lipaedemia, glycemia, anthropometrics, blood pressure and energy expenditure will be investigated.
- Conditions
- Energy Expenditure, Metabolic Syndrome, Anthropometry, Body Composition
- Trial name
- 12OATS (NCT06951386)
- Testing
- with short-chain fatty acids enriched drink, unenriched oat drink
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- KU Leuven
Cardiovascular Diseases, Vasodilation
Effects of n-3 Polyunsaturated Fatty Acids and Antioxidants on Postprandial Hyperlipidemia and Vascular Function in Men
Diet has long been used as a way to provide enough nutrients to an individual in order to meet metabolic requirements. However, recent scientific advancements have suggested that beyond meeting nutrition needs, diet may also be…
- Trial name
- NCT00296595
- Testing
- Nutrition
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Laval University
Type 2 Diabetes, Atherosclerosis
The Copenhagen Insulin and Metformin Therapy Trial
Type 2 Diabetes Mellitus patients (T2DM) have an increased mortality rate due to macrovascular disease. The primary objective of the study is to evaluate the effect of an 18-month treatment with metformin versus placebo in…
- Conditions
- Type 2 Diabetes, Atherosclerosis, Arteriosclerosis
- Trial name
- CIMT (NCT00657943)
- Testing
- metformin, insulin detemir, insulin aspart + insulin aspart protamin
- Where
- 9 sites in Denmark
- Volunteers
- 415 people
- Sponsor
- Steno Diabetes Center Copenhagen
Adiposity
Role of Interleukin (IL)-1 in Postprandial Fatigue - The Chäschüechli 2 Study
Role of IL-1 in postprandial fatigue - The Chäschüechli 2 Study It is a randomized, single dose, placebo-controlled, double blind, cross-over, proof-of-concept study. 16 healthy young men will be included in this study.
- Trial name
- Chäs2 (NCT02916355)
- Testing
- Anakinra, NaCl
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Functional Dyspepsia
Ghrelin and Gastric Emptying in Children With Functional Dyspepsia
The purpose of this research is to see if there are differences between children who have FD and children without FD in the ability of the stomach to empty food and/or in ghrelin hormone levels before and after eating.
- Trial name
- GHR (NCT01591174)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Premature, Necrotizing Enterocolitis
Intestinal Perfusion After Feeding in Preterm and Term Infants
This is a pilot exploratory observational prospective cohort phase I study. In this study, we will gather preliminary data to evaluate (i) the magnitude of changes in blood flow in the bowel before and after feeding and (ii) the…
- Trial name
- NCT06319326
- Testing
- Evaluation of intestinal perfusion with color Doppler abdominal ultrasound before and after feeding.
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Glycemic Response
Avocado Fruit on Postprandial Markers of the Glycemic Response, Satiety/Appetite and Cardiometabolic Risk
The primary goal is to characterize the acute effects of avocado intake on glycemic and satiety/ appetite responses in relatively healthy overweight / obese adults.
- Trial name
- AVOC1 (NCT02479048)
- Testing
- Test meal 1, Test meal 2, Control Meal (CM)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Diabetes Mellitus
Effect of Insulin Glulisine vs Regular Human Insulin on Postprandial Endothelial Function in Type 2 Diabetes
The primary objective of the study is to evaluate the postprandial time course of nitrotyrosine after injection of insulin glulisine compared with regular human insulin.
- Trial name
- NCT00562133
- Testing
- Insulin Glulisine, Insulin
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- IKFE Institute for Clinical Research and Development
Glycemic Response
Assessment of the Glycemic Responses to Nutritional Products (v2.0)
This study assesses the glycemic responses to nutritional products. During a study visit fasted subjects will consume one serving of the reference product or the test product.
- Trial name
- GLIN#2 (NCT05308147)
- Testing
- First Reference product, Second Reference product, Third Reference product
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Postprandial Period, Biomarkers
Postprandial Metabolism in Healthy Young Subjects
This study aims to describe the dynamic changes in nutritional biomarkers in the blood during the postprandial period, i.e. the time period from the last meal and into the fasting state.
- Conditions
- Postprandial Period, Biomarkers, Fasting
- Trial name
- PoMet (NCT04989478)
- Testing
- Fasting
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Type 1 Diabetes (T1D)
Mealtime or Post-meal Dosing of URLi in Medtronic 780G Hybrid Closed Loop System
This is a pilot study to compare premeal to postmeal dosing of ultra rapid lispro insulin (URLi) used in a MiniMed 780G system hybrid closed loop system.
- Trial name
- NCT06600776
- Testing
- Ultra Rapid Lispro (URLi), Insulin pump with continuous glucose monitoring (CGM)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Spinal Cord Injury
Coronary Artery Calcification Score and Risk Factors for Coronary Artery Disease in Persons With Spinal Cord Injury
Although conventional risk factors for coronary heart disease (CHD) have been identified and routinely used to determine risk for CHD in the general population, a systematic approach to determine population-specific risk for CHD…
- Trial name
- CAC (NCT02007226)
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Postprandial Glycemic Response, Postprandial Hyperglycemia
Short, Simple, Exercise to Improve Circadian Dependent Postprandial Glycemic Responses
The goal of this clinical trial is to test whether one minute of stair stepping at a comfortable pace can reduce blood sugar after meals.
- Conditions
- Postprandial Glycemic Response, Postprandial Hyperglycemia, Postprandial Insulin
- Trial name
- NCT05783752
- Testing
- Stair Stepping, No exercise control
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Oxidative Stress, Antioxidants
Effect of Acute Red Raspberry Consumption on Post-prandial Oxidative Stress
Eight healthy adult subjects will be given a meal of one, two or four cups red raspberries, or two slices white bread with or without 200 mg vitamin C, after an overnight fast and consumption of a low polyphenol diet for two…
- Trial name
- NCT01242033
- Testing
- red raspberries, bread controls
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Postprandial Glycemic Response
A Study to Investigate the Effect of SFF on Glucose and Insulin Responses
This goal of this clinical study is to investigate the postprandial glycemic and insulinemic response in healthy adults after the consumption of: 1. Sugars from Fiber in comparison with dextrose 2.
- Trial name
- NCT05587426
- Testing
- SFF, Glucose, SFF chocolate chips
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge Glycoscience
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