Clinical trials: Postprandial Glucose
Hyperglycemia
The Effect of American Ginseng Root and Its Components on Glycemia in Healthy Individuals
To determine the effect of polysaccharides from American ginseng root on postprandial glycemia in healthy individuals.
- Trial name
- NCT00367926
- Testing
- American ginseng root / polysaccharides
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Risk Factor Modification Centre
Obesity, Diabetes
Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes
Quercetin is a compound naturally found in various foods. It may have some role in the treatment of obesity and diabetes. The purpose of this study is to investigate research volunteers with obesity or obesity with type 2…
- Trial name
- NCT00065676
- Testing
- Quercetin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gestational Diabetes Mellitus (GDM)
Determining the Effect of Food Ordering on Blood Glucose In Gestational Diabetes Mellitus (DEFI-GDM)
The goal of this clinical trial is to determine whether the sequence of macronutrient consumption affects post-prandial glycaemia in women with gestational diabetes mellitus.
- Trial name
- DEFI-GDM (NCT06896799)
- Testing
- Visit 1: Protein/fat then carbohydrate. Visit 2: Carbohydrate then protein/fat., Visit 1: Carbohydrate then protein/fat. Visit 2: Protein/fat then carbohydrate.
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Queen's University, Belfast
Type 1 Diabetes Mellitus, Glycemic Variability
Impact of Dietary Fat and Menstrual Cycle Phases in Type 1 Diabetes
This clinical trial aims to evaluate how variations in dietary fat content and hormonal status influence postprandial glycemic response in individuals with type 1 diabetes (T1D), with a special focus on women.
- Conditions
- Type 1 Diabetes Mellitus, Glycemic Variability, Sex Characteristics, Menstrual Cycle
- Trial name
- DIABETEXX/3 (NCT07278063)
- Testing
- Low Fat Mixed Meal, High Fat Mixed Meal
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Type 2 Diabetes
Effects of Pramlintide on Endogenous Production of Very-low-density-lipoprotein (VLDL)-Triglyceride and Glucose in the Post Prandial State in T2DM
Diabetes affects almost 21 million people in the United States. In this study we will test a drug called Pramlintide(Symlin), and see how it works to lower blood sugar and fat levels after a meal.
- Trial name
- NCT00732147
- Testing
- Pramlintide acetate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Blood Sugar (Glucose) Control, Blood Vessel (Vascular) Dysfunction
Whey Protein Effects on Gycemic Control and Vascular Function
Risk for heart and blood vessel diseases is increased when blood sugar rises. Blood vessel dysfunction is common to such diseases. Elevated blood sugar after eating promotes blood vessel dysfunction.
- Trial name
- NCT01814358
- Testing
- Whey protein powder, Control protein
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
The Focus of the Study is Healthy Volunteers
Appetite Regulation by a Breakfast Soft Bread
The aim of this study is to evaluate the appetite rating of a soft bread with a high content of fibre and protein (Puravita Breakfast®) as well as its capacity to modulate postprandial levels of glucose, insulin and…
- Trial name
- NCT02090049
- Testing
- Puravita Breakfast, Control
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Puratos
Postprandial Hypoglycemia
Glucose Response to a Formula for Patients at Risk of Hypoglycaemia
This study assesses the glycemic responses to several nutritional products.
- Trial name
- EFFECT (NCT05676385)
- Testing
- First concept product (containing 50 grams of carbohydrates), Second concept product (containing 50 grams of carbohydrates), Reference product (containing 50 grams of carbohydrates)
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Diabetes, Diabetes Mellitus, Type 1
A Comparison of Postprandial Glucose After a MMTT, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study in Subjects With Type 1 Diabetes
This is an inpatient treatment, double-blind, randomized, 3-way crossover study in T1DM subjects using insulin pump therapy.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Type1diabetes, Diabetes Mellitus
- Trial name
- NCT04956263
- Testing
- YG1699, Dapagliflozin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Youngene Therapeutics Inc., Ltd.
Obesity, Pre-Diabetes
Effect of Food Order on Postprandial Glucose Excursions in Pre-Diabetes
The natural history of type 2 diabetes commonly follows a pattern of postprandial dysregulation followed by fasting hyperglycemia leading to overt type 2 diabetes.
- Trial name
- NCT03536364
- Testing
- Food Order, Carbohydrate Last, Vegetables first
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Diabetes Mellitus, Type 2
A Repeatability Study of Fatty Acid Uptake Using PET/MR Imaging in Patients With T2DM and Non-diabetic Control Subjects
The main purpose of this study is to evaluate the overall variation in the assessment of fatty acid uptake and blood flow in adipose tissue and skeletal muscle in the fasted and postprandial states by evaluating the repeatability…
- Trial name
- AM05 (NCT05132335)
- Testing
- Imaging Biomarkers
- Where
- 2 sites in Finland
- Volunteers
- 19 people
- Sponsor
- Turku University Hospital
Glucose Metabolism Disorders
Relative Contribution of Brain Insulin Action for Postprandial Metabolism
The goal of this clinical trial is to clarify (i) the contribution of brain insulin action on regulation of systemic metabolism, (ii) sex-specific differences in the central regulation and (iii) the influence of the menstrual…
- Trial name
- BrainInsPPM (NCT06295640)
- Testing
- Oral glucose tolerance test with double-tracer dilution and intranasal insulin spray
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Type 2 Diabetes, Obese
Postprandial Metabolism After Bariatric Surgery in Type 2 Diabetes
Bariatric surgery procedures have now been firmly demonstrated to lead to significant improvement and even, in many cases, complete reversal of abnormal glucose homeostasis in type 2 diabetes (T2D).
- Trial name
- CB4 (NCT02815943)
- Testing
- biliopancreatic diversion with duodenal switch, sleeve gastrectomy, liquid meal
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Diabetes Mellitus, Type 1
Exercises on Children and Adolescents With Type 1 Diabetes Mellitus (T1DM)
This study aimed to assess the effect of aerobic and resistance exercise on postprandial blood glucose levels in children and adolescents aged 10 - 18 years, diagnosed with type 1 diabetes mellitus (T1DM) for at least 1 year…
- Trial name
- NCT06680557
- Testing
- Aerobic and resistance exercises
- Where
- Egypt
- Volunteers
- 49 people
- Sponsor
- Sohag University
Postprandial Hyperglycemia, Heart Rate Variability
Effect of Feet and Calf Heating on Glucose Tolerance
Determine the effect of feet and calf heating on glucose tolerance relative to thermoneutral control. Heat will be administered using hot water (40 degrees celsius).
- Trial name
- NCT04232098
- Testing
- Heat to ankle, Heat to calf
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Diabetes Mellitus, Type 2
A Study to Evaluate the Effect of JNJ-28431754 (Canagliflozin) on Post-Meal Glucose in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the effect of canagliflozin on post-meal glucose blood levels in patients with Type 2 Diabetes Mellitus.
- Trial name
- NCT01381887
- Testing
- Canagliflozin 300mg/Canagliflozin 150mg, Canagliflozin 300mg
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Type2 Diabetes
Triglyceride Rich Lipoproteins and Platelet Activation in Type 2 Diabetes
To investigate in vitro the effect of triglyceride rich lipoproteins (TGRL) obtained in type 2 diabetic women in the fasting state and following a randomized isocaloric lipid rich breakfast on control human platelets Randomized…
- Trial name
- COMPLETE (NCT03561571)
- Testing
- butter based breakfast, Chocolate spread based breakfast
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Hospices Civils de Lyon
Prediabetes, Normoglycemic
Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile, Gastric Emptying and GLP-1 Release in Normoglycemic and Prediabetic Subjects
Aim of the study is to investigate the postprandial response on blood glucose, insulin, C-peptide, incretin response and gastric emptying after intake of collagen hydrolysate compared to placebo in normoglycemic and in…
- Trial name
- NCT06789263
- Testing
- Collagen hydrolyzed peptides
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Nephrotic Syndrome, Lipodystrophy
Effects of Meal Macronutrients on Postprandial Lipids
Background: Abnormal fats in the blood can lead to many problems, including heart disease. Researchers want to learn more about how eating meals with different levels of nutrients affects fats in the blood.
- Conditions
- Nephrotic Syndrome, Lipodystrophy, Metabolic Syndrome, Healthy Volunteer
- Trial name
- NCT07313787
- Testing
- High carb then high fat breakfast, High fat then high carb breakfast
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 1 Diabetes Mellitus
Does Protein and Fat Content of Meal Increase Glucose Concentrations
The study investigated the effects of fat protein counting (CFP) in addition to carbohydrate (CARB) counting for calculating prandial insulin dosage on blood glucose profile in patients with type 1 diabetes (T1D) on basal-bolus…
- Trial name
- NCT03333525
- Testing
- Calculation of insulin dosages for different meals
- Volunteers
- 30 people
- Sponsor
- TC Erciyes University