Clinical trials: Postprandial Inflammation
Inflammation
A Study of Tomato Products and Disease Risk
The purpose of this research study is to test whether certain compounds in tomatoes will help reduce factors in the subject's blood associated with disease risk.
- Trial name
- TOM (NCT00966550)
- Testing
- Tomato, Non-tomato
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Metabolic Syndrome, Inflammation
Impacts of Aronia on Inflammation and the Gut Microbiome
The overall goal of this project is to determine the inflammation lowering impact of anthocyanin-rich Aronia berries. Inflammation is an underlying mechanism driving the development of several diseases.
- Conditions
- Metabolic Syndrome, Inflammation, Hypertriglyceridemia, Obesity
- Trial name
- NCT04128839
- Testing
- Aronia berry juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Montana State University
Hypertriglyceridemia, Inflammation
Impacts of Lentils on Metabolism and Inflammation
The overall goal of this investigation is to determine gut microbiome dependent and independent impacts of pulse consumption on metabolic resilience and metabolic risk profiles for type 2 diabetes (T2D) and cardiovascular disease…
- Conditions
- Hypertriglyceridemia, Inflammation, Waist, Hypertriglyceridemic
- Trial name
- NCT04283448
- Testing
- Dietary Lentil, Control
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Montana State University
Metabolic Syndrome
Olive Oil and Nampt on Postprandial Inflammation and Atherosclerosis in the Setting of Metabolic Syndrome
The metabolic syndrome may be defined as the constellation of cardiovascular disease (CVD) risk factors that comprises obesity, type 2 diabetes, dyslipidemia, and hypertension.
- Trial name
- OLNAMS (NCT02061267)
- Testing
- Niacin, Saturated meal, Monounsaturated meal
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Inflammation, Obesity
Impact of High-fat Meals Varying in Fatty Acid Composition on Adipose and Systemic Metabolic-inflammatory Responses
Cardiometabolic disorders are a leading cause of death worldwide. Replacing saturated fatty acids (SFA) with unsaturated fatty acids is recommended as a way of lowering cardiometabolic disease risk.
- Conditions
- Inflammation, Obesity, Inflammatory Response, Cardiovascular Diseases
- Trial name
- NCT03712579
- Testing
- SFA-Rich Meal, MUFA-Rich Meal
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy, Overweight
Postprandial Effects of High-fat Meals With Different Dairy Products on Lipid Metabolism and Inflammation
The aim of this project is to elucidate how high-fat meals with different kinds of dairy products affect postprandial responses of lipid metabolism and inflammatory markers in healthy and obese subjects.
- Conditions
- Healthy, Overweight, Obesity
- Trial name
- NCT02836106
- Testing
- Butter, Cheese, Whipped cream
- Where
- Norway
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Heart Diseases, Diabetes
Fast Food Study: Assessment of the Effects of Fast-Food on Inflammatory Markers
The purpose of this research study is to determine whether eating a fast food meal (high in saturated fat) will result in greater increases in inflammatory markers than eating a meal with low levels of saturated fat and higher…
- Conditions
- Heart Diseases, Diabetes, Obesity
- Trial name
- NCT00233311
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Obesity
Effect of an Antiinflammatory Diet on Postprandial Gene Expression of Mononuclear Cells of Adult Obese Women
Obesity is one of the major health problems worldwide. The consumption of healthy-dietary patterns can be difficult in some countries due to the availability of certain foods. Suggestion of alternative foods could be a necessity.
- Trial name
- NCT04920409
- Testing
- FAWGT diet, Usual diet (UD)
- Where
- Colombia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universidad de Caldas
Inflammation
The Effects of Antioxidants in Blueberry Powder on Inflammation Induced by a Single High Fat Meal.
The goal of the study is to find out whether a high fat meal increases blood lipids and causes monocyte (white blood cell) activation, and whether blueberry intake at the same meal lessens monocyte activation in healthy people.
- Trial name
- FL89 (NCT01594008)
- Testing
- Breakfast meal with 2 serving equivalents of blueberries, Breakfast meal with 4 serving equivalents of blueberries
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Type 2 Diabetes Mellitus
Postprandial Dysmetabolism
Type 2 diabetes (T2D) is a common disease associated with multiple complications and an increased risk of cardiovascular morbidity and mortality. Also, it is a heavy economical burden on society.
- Trial name
- PPDysMet (NCT00813215)
- Testing
- Meal challenge
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Oxidative Stress, Endothelial Function
Tahini, Antioxidant Status and Endothelial Function
Cardiovascular disease (CVD), a cluster of disorders that affect heart and blood vessels, is the leading cause of morbidity and mortality around the world and is responsible for 17.9 million deaths annually worldwide.
- Conditions
- Oxidative Stress, Endothelial Function, Blood Pressure, Arterial Stiffness
- Trial name
- NCT04608747
- Testing
- Tahini
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Inflammation, Obesity
Impact of Dairy Products on Postprandial Inflammation
The study will quantitatively evaluate the systemic, postprandial inflammatory and metabolic response to the ingestion of three different meals in obese subjects.
- Conditions
- Inflammation, Obesity, Nutritional Intervention
- Trial name
- NCT01885416
- Testing
- consumption of test meal based on dairy products, consumption of high fat test meal without dairy products, consumption of high fat test meal with dairy products
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Agroscope Liebefeld-Posieux Research Station ALP
Metabolic Syndrome
Grape Seed Extract and Postprandial Oxidation and Inflammation
The purpose of this study is to determine whether taking grape seed extract prior to eating a high fat meal will reduce the inflammatory response in people with the metabolic syndrome.
- Trial name
- GSEMetS (NCT01190358)
- Testing
- Grape seed extract
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of California, Davis
Obesity, Postprandial Lipemia
Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects
The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.
- Conditions
- Obesity, Postprandial Lipemia, Atherosclerosis, Inflammation
- Trial name
- NCT00863564
- Testing
- Caseine, Cod, Gluten
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Cardiometabolic Risk
Investigation of the Acute Effect of Novel Olive Oil on Postprandial Oxidative Stress Biomarkers (BioliveCT)
The purpose of this study was the investigation of the hypothesis that the enhancement of a refined olive oil with orange peel extract, may improve the postprandial lipidemic, glycemic profile and blood oxidative status, of…
- Trial name
- BioliveCT (NCT05771571)
- Testing
- Functional olive oil, enhanced with orange peel extract, Control
- Where
- Greece
- Volunteers
- 21 people
- Sponsor
- University of the Aegean
Metabolic Syndrome, Obesity
Determine How Consumption of Dairy Fat as Cheese Influences Inflammation-Phase 2
Phase 2 of this study involves determining how consumption of cheese compared with a non-dairy cheese substitute influences inflammation over a six hour period.
- Trial name
- NCT01803633
- Testing
- Cheddar cheese, Vegan cheese
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hyperglycemia, Inflammation
Acute Effects of Postabsorptive and Postprandial Physical Activity
Physical activity performed in the postprandial state has the ability to blunt postprandial glycemia acutely, even as a result of very light or small amounts of postprandial physical activity.
- Trial name
- NCT02554669
- Testing
- postprandial and postabsorptive physical activity on treadmill
- Volunteers
- 12 people
- Sponsor
- Inland Norway University of Applied Sciences
Effect of Resveratrol and Curcumin on Inflammation
Effect of Antioxidant Intake on Cardiovascular Risk
The general objective of this project is to investigate the acute effect of consuming a dietary supplement combining resveratrol and curcumin on the inflammatory response following the consumption of a high-fat meal in healthy…
- Trial name
- NCT01964846
- Testing
- Resveratrol, curcumin
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Laval University
Oxidative Stress, Inflammation Biomarkers
Postprandial Effect of Olive Leaf Biscuits and Tea Consumption on Blood Biomarkers in Healthy Individuals
This randomized controlled nutritional intervention study aims to investigate the bioactivity of dried olive leaves in biscuit and tea preparations, focusing on their postprandial effects on selected biomarkers and plasma…
- Trial name
- OliherbCT (NCT06983145)
- Testing
- Olive Leaf tea
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the Aegean
Cardiovascular Diseases
Effectiveness of Sacha Inchi Supplementation on Postprandial Inflammation
The postprandial state increases triglyceride-rich lipoproteins and lipopolysaccharide (LPS) levels, promoting cellular lipids accumulation, insulin resistance, increased inflammatory markers and the formation of foam cells, a…
- Trial name
- ESISOPI (NCT02886169)
- Testing
- High fat meal with Sacha Inchi, high saturated fat meal
- Where
- Colombia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Icesi