Clinical trials: Postprandial Lipids Metabolism
Type 2 Diabetes, Postprandial Oxidative Stress
Postprandial Insulin Secretion, Oxidative Stress and Gastrointestinal Peptides in Patients With Type 2 Diabetes Versus Healthy Subjects
Insulin secretion, plasma lipids, oxidative stress markers and gastrointestinal peptides will be measured in patients with type 2 diabetes versus healthy subjects in a fasting status and in response to standard meals (at times…
- Trial name
- NCT01572402
- Testing
- Bagueutte Cheese Gourmet (Crocodille), Cous-cous sandwich, McCountry sandwich (McDonald's)
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Functional Immune Response, Postprandial Bioavailability DHA
The Effect of Algae Oil Supplements on Functional Immune Response and Bioavailability of Lipids in Blood, a Pilot Study
In this explorative study we will investigate whether two sustainable oil supplements yield equivalent results to fish oil supplements in terms of postprandial immune response, among elderly adults, after standardization of the…
- Conditions
- Functional Immune Response, Postprandial Bioavailability DHA, Fatty Acid Metabolism
- Trial name
- ALG (NCT07086573)
- Testing
- Algae oil 1, Algae oil 2, Fish oil (control)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maartje van den Belt
Hyperlipidemias, Triglycerides High
Effects of MCDG Oil on Postprandial Lipid Metabolism
It is well known that medium chain triglycerides (MCTs) and diacylglycerols (DGs) have effects on lowering circulating triglycerides (TGs).
- Trial name
- NCT03415568
- Testing
- LCT oil, MCDG oil
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Diabetes, Liver
Foxtail Millet Based Dietary Intervention for Postprandial Glycemic Management Among Obese Diabetic Patients
This randomized controlled trial evaluated the effectiveness of foxtail millet (Setaria italica (L.) P. Beauv.) muffin supplementation on postprandial glycemic management among obese patients with type 2 diabetes mellitus.
- Conditions
- Diabetes, Liver, Lipid Profiles
- Trial name
- NCT07699250
- Testing
- T0, T1, T2
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Type 2 Diabetes Mellitus
Effects of PCSK9 Inhibition by Evolocumab on Postprandial Lipid Metabolism in Type 2 Diabetes
Postprandial lipemia is highly prevalent in type 2 diabetes subjects even with normal fasting triglyceride values. Humans are mostly in a postprandial rather than in a fasting state and therefore non-fasting triglyceride values…
- Trial name
- NCT02948777
- Testing
- Evolocumab
- Where
- Finland
- Volunteers
- 14 people
- Sponsor
- Marja-Riitta Taskinen
Acromegaly
Growth Hormone, IGF-1 and Medical Treatment in Acromegaly: Are There Effects on Gut Hormone Physiology and Postprandial Substrate Metabolism?
Acromegaly is a rare hormonal disorder leading to increased morbidity and mortality. In the vast majority of cases, a pituitary somatotroph cell adenoma causes excess growth hormone (GH) secretion, leading to hepatic…
- Trial name
- NCT02152124
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Hyperlipemia, Carbohydrate Inducible
Milk as a Recovery Beverage After Exercise for Improving Metabolic Health
Fasting blood fat levels (triglycerides) are often used to assess risk of heart disease but the level of fats in the blood after a meal is actually a stronger risk factor.
- Trial name
- NCT03154216
- Testing
- Exercise, Drink
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Hypoglycemia, Hyperglycemia
Influence of Dietary Fiber-rich Meals on Gene Expression and Postprandial Glucose and Lipid Response
The aim of this study is to Measure the effect on gene expression in leukocytes from a meal rich in oat bran Investigate the postprandial glucose, insulin and triglyceride responses after intake of meals containing fiber from…
- Trial name
- NCT01005342
- Testing
- Oat bran, Spray-dried oat drink, Rye bran
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Abdominal Obesity, Postprandial Lipemia
Alternating Energy Intake and Blood Fat Content After a Meal
Increasing evidence suggests that meal timing affects metabolic health. For example, intermittent fasting (IF) may have positive effects on plasma glucose and lipid levels, insulin sensitivity, and blood pressure.
- Conditions
- Abdominal Obesity, Postprandial Lipemia, Lipid Metabolism, Glucose Metabolism
- Trial name
- NCT04894526
- Testing
- Alternating Energy Intake, Regular Energy Intake
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hypertriglyceridemia
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
The primary objective of the study is to determine the effect of MAR001 as compared to placebo on levels of the triglycerides (TG) in the postprandial state in adults with elevated TG.
- Trial name
- NCT07199309
- Testing
- MAR001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marea Therapeutics
Post-prandial Glycaemic Response, Postprandial Lipids Metabolism
Postprandial Responses to Fish Intake
Fish consumption has been increasing in recent decades due to consumer interest in the positive health effects of regular food intake, among other factors.
- Conditions
- Post-prandial Glycaemic Response, Postprandial Lipids Metabolism, Postprandial Metabolism
- Trial name
- PREFish (NCT06757608)
- Testing
- Assessment of postprandial metabolism after intake of different meat
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postprandial Period, Lipemia
Vascular Effects of Triglyceride-rich Lipoproteins
Many types of cardiovascular disease begin when the layer of cells lining blood vessels (endothelial cells) start to function abnormally.
- Conditions
- Postprandial Period, Lipemia, Vasodilation, Vascular Resistance
- Trial name
- NCT01618071
- Testing
- High-fat meals varying in their fatty acid composition
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy Subjects
Nutrigenomics Investigation of the Body's Metabolic Response to 2 Different Meal Challenges
The purpose of this study is to investigate the biological response to a metabolic stress, given in the form of a high carbohydrate or fat meal in normal weight, overweight and obese individuals and to further explore these…
- Trial name
- MECHE (NCT01172951)
- Testing
- Oral glucose tolerance test, Oral lipid tolerance test
- Where
- 2 sites in Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Hyperlipidemias, Nutritional and Metabolic Diseases
Lean Seafood Intake and Postprandial Metabolism
Despite numerous studies of meal components in humans, little is still known about how different meals influence on metabolism. The purpose of this study is to a gain knowledge of how a balanced test meal with either lean seafood…
- Conditions
- Hyperlipidemias, Nutritional and Metabolic Diseases, Nutrition Disorders, Metabolic Diseases
- Trial name
- LeSIP (NCT01708681)
- Testing
- Lean seafood, Meat, egg, milk
- Where
- Norway
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Institute of Nutrition and Seafood Research, Norway
Type II Diabetes Mellitus
Effects of a Spiced Meat Patty on Inflammation in Men With Type 2 Diabetes
Polyphenols belong to the largest group of secondary metabolites produced by plants, mainly, in response to biotic or abiotic stresses such as infections, wounding, UV irradiation, exposure to ozone, pollutants, and other hostile…
- Trial name
- NCT01076829
- Testing
- Spice polyphenols
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Triglycerides, Weight Gain Trajectory
Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists
The goal of this clinical trial is to learn if drug RDX-002 works to treat high levels of fat (known as triglycerides, or TGs) in the blood in adults. It will also learn about the safety of drug RDX-002.
- Conditions
- Triglycerides, Weight Gain Trajectory, Cholesterol, Elevated
- Trial name
- NCT06640972
- Testing
- RDX-002
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Response Pharmaceuticals
Hypertriglyceridemia
Effects Of Consumption Of A Highly Mineralized Sodium Bicarbonated Water On Blood Lipid Profile
The aim of the study is to assess the beneficial effect of the short term consumption of the highly mineralized bicarbonated sodium water on blood lipid parameters compared to a low mineralized water.
- Trial name
- NCT01819636
- Testing
- sparkling highly mineral bicarbonated sodium water
- Where
- 3 sites in France
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Neptune
Healthy, Overweight
Postprandial Effects of High-fat Meals With Different Dairy Products on Lipid Metabolism and Inflammation
The aim of this project is to elucidate how high-fat meals with different kinds of dairy products affect postprandial responses of lipid metabolism and inflammatory markers in healthy and obese subjects.
- Conditions
- Healthy, Overweight, Obesity
- Trial name
- NCT02836106
- Testing
- Butter, Cheese, Whipped cream
- Where
- Norway
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Hypertriglyceridemia
Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)
Postprandial lipid metabolism will be evaluated in patients with hypertriglyceridemia and normo-lipidemic controls; different fats will be used (saturated fatty acids, mon-unsaturated fatty acids and medium chain fatty acids) for…
- Trial name
- NCT03846908
- Testing
- MCT, SFA, MUFA
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Hyperlipemia
Effect of Consumption of Bagel Without Palm Oil on Postprandial Lipidemia
Postprandial lipemia produced by fat intake is a major risk factor for the development of cardiovascular diseases (CVD), the most important cause of disease and death in the Western world.
- Trial name
- PALMFREE (NCT03950752)
- Testing
- Optimized Bagel, Conventional Bagel
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain