Clinical trials: Postprandial Lipids Metabolism
Hypertriglyceridemia
Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)
Postprandial lipid metabolism will be evaluated in patients with hypertriglyceridemia and normo-lipidemic controls; different fats will be used (saturated fatty acids, mon-unsaturated fatty acids and medium chain fatty acids) for…
- Trial name
- NCT03846908
- Testing
- MCT, SFA, MUFA
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Inflammation, Metabolic Disorder
Impact of Aronia Berry Consumption on Inflammation, Metabolites, and the Gut Microbiome
The goal of this project is to elucidate interactions between the gut microbiome, anti-inflammatory/anti-oxidant food metabolomic signatures, and human inflammation phenotypes.
- Conditions
- Inflammation, Metabolic Disorder, Hypertriglyceridemia
- Trial name
- NCT05255718
- Testing
- Aronia juice
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Montana State University
Hypertriglyceridemia
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
The primary objective of the study is to determine the effect of MAR001 as compared to placebo on levels of the triglycerides (TG) in the postprandial state in adults with elevated TG.
- Trial name
- NCT07199309
- Testing
- MAR001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marea Therapeutics
Healthy, Overweight
Postprandial Effects of High-fat Meals With Different Dairy Products on Lipid Metabolism and Inflammation
The aim of this project is to elucidate how high-fat meals with different kinds of dairy products affect postprandial responses of lipid metabolism and inflammatory markers in healthy and obese subjects.
- Conditions
- Healthy, Overweight, Obesity
- Trial name
- NCT02836106
- Testing
- Butter, Cheese, Whipped cream
- Where
- Norway
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Type 2 Diabetes Mellitus
Postprandial Dysmetabolism
Type 2 diabetes (T2D) is a common disease associated with multiple complications and an increased risk of cardiovascular morbidity and mortality. Also, it is a heavy economical burden on society.
- Trial name
- PPDysMet (NCT00813215)
- Testing
- Meal challenge
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Metabolic Syndrome
Effects of Dietary Polyphenols and ω-3 Fatty Acids on Cardiovascular Risk Factors in High Risk Subjects
The aim of this study is to explore if a 8-weeks dietary intervention with polyphenols and omega 3 fatty acids (alone or combined) may be effective on postprandial lipids metabolism and other cardiovascular risk factors in people…
- Trial name
- Etherpaths (NCT01154478)
- Testing
- Diet rich in omega-3 fatty acids, Diet rich in polyphenols, Control diet
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- Federico II University
Healthy, Familial Hypercholesterolemia
Postprandial Response After Intake of Meals With Different Fatty Acid Composition
The aim of the study is to understand more about how different fatty acids modulate postprandial lipid metabolism and inflammatory response.
- Trial name
- NCT02729857
- Testing
- SFA muffin, PUFA muffin
- Where
- Norway
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Postprandial Effect of Carbohydrate Beverage Consumption
Fat Burning After a Meal
The purpose of the study is to determine how adding a carbohydrate beverage to a meal with different protein levels affects the rate at which one's body burns fats, sugars, and proteins.
- Trial name
- NCT02211599
- Testing
- 15% protein, 30% protein, Sweetened beverage
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Sedentary Lifestyle, Dyslipidemias
Effects of Exercise on Fructose-induced Postprandial Lipemia
Cardiovascular Diseases (CVDs) are the leading causes of death in the world and in Brazil. In 2001, 12.45 million deaths on the globe (21% of the total) were caused by some CVD.
- Conditions
- Sedentary Lifestyle, Dyslipidemias, Lipid Metabolism Disorders, Carbohydrate Inducible Hyperlipemia
- Trial name
- NCT03173495
- Testing
- FRUCTOSE, DEXTROSE, EXERCISE
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Hypertriglyceridemia, Metabolic Syndrome
Intestines and Liver Contribution to Fasting Postprandial Hypertriglyceridemia
Fasting and postprandial hypertriglyceridemia (HTG) depends on increased production of intestinal triglyceride rich lipoproteins in patients with isolated fasting hypertriglyceridemia.
- Trial name
- TRIGPP (NCT02898142)
- Testing
- Postprandial test
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postprandial Lipaemia
Optimizing Dietary Fatty Acids to Lower Metabolic Risk Factors Among Canadians
Scientists believe that what happens to dietary fats after they are eaten, especially how they cleared from the blood, affects risks of heart disease and diabetes is more important than measuring blood fats after an overnight…
- Trial name
- NCT01067911
- Testing
- Butter and Vegetable oils from soy, flaxseed, high oleic safflower and canola, In this study subjects will consume test meals containing vegetable oils (soy, flaxseed, high oleic safflower and canola) and butter
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Type 2 Diabetes Mellitus
Lipid, Glycemic, and Insulin Responses to Meals Rich in Different Fatty Acids
A meal rich in very-long chain omega-3 fatty acids or oleic acid may lower postprandial insulin levels in comparison to a meal rich in linoleic acid or palmitic acid.
- Trial name
- NCT00479791
- Testing
- Test meals rich in different fatty acids
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Glucose Metabolism, Lipid Metabolism
Effects of a Potato-based Food Pattern vs a Rice / Pasta-based Food Pattern on Cardiometabolic Health
The researchers investigate the effect of long-term (12-weeks) consumption of diets rich in boiled potatoes versus those rich in rice or pasta on established cardiovascular risk parameters.
- Trial name
- LoPoCardio (NCT04851041)
- Testing
- Potato, Pasta/rice
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Healthy Nutrition
Sex Differences in Metabolism Following a High-fat Meal
Long-term consumption (i.e., several weeks to months) of a diet that is high in fat (>35% daily calories from fat) is associated with the development of insulin resistance, a condition that can lead to a diagnosis of type 2…
- Trial name
- HFM (NCT05332301)
- Testing
- High-fat test meal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kirsten Bell
Healthy, Nutrition, Healthy
Postprandial Metabolic and Appetite Responses to Different Food Intake Sequences in Athletes
Emerging evidence suggests that following a 'carbohydrate-last meal pattern', wherein foods rich in protein, fat, fiber, and/or polyphenols are consumed before sources of simple carbohydrate (CHO) in a meal, results in reduced…
- Conditions
- Healthy, Nutrition, Healthy, Postprandial Hyperglycemia, Hunger
- Trial name
- NCT06365385
- Testing
- Carbohydrate-last meal pattern, Carbohydrate-first meal pattern
- Where
- Portugal
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Cardiovascular Risk Factor, Lipaemia
Effect of Lactose on Blood Lipids
This study aims to determine to what extent ingestion of free sugars influence postprandial triglyceridaemia in men and women.
- Conditions
- Cardiovascular Risk Factor, Lipaemia, Metabolic Disease
- Trial name
- NCT04924530
- Testing
- Maltodextrin, Sucrose, Lactose
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bath
Spinal Cord Injuries
Postprandial Lipid Tracer and Exercise in Spinal Cord Injury
This study investigates the effect of upper extremity exercise on postprandial lipemia (PPL) in persons with spinal cord injury (SCI).
- Trial name
- PPLT (NCT03691532)
- Testing
- Seated control (CON), Arm cycle exercise (ACE), Liquid meal
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Miami
Diabetes Mellitus
Efficacy of Alogliptin and With Pioglitazone in Patients With Type 2 Diabetes.
The purpose of this study is to compare the efficacy of Alogliptin, once daily (QD), taken by itself and with pioglitazone on postprandial lipid measures in type 2 diabetes.
- Trial name
- NCT00655863
- Testing
- Alogliptin and Pioglitazone, Alogliptin
- Where
- 2 sites in Netherlands, Sweden
- Volunteers
- 71 people
- Sponsor
- Takeda
Familial Dysbetalipoproteinemia, Hyperlipoproteinemia Type III
Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Patients With Familial Dysbetalipoproteinemia
Patients with familial dysbetalipoproteinemia (FD) have increased triglycerides, non-high-density lipoprotein cholesterol (non-HDL-C), beta VLDL, premature atherosclerosis and cardiovascular disease.
- Trial name
- EVOLVE-FD (NCT03811223)
- Testing
- Evolocumab Auto-Injector [Repatha]
- Volunteers
- 30 people
- Sponsor
- UMC Utrecht
Postprandial Period, Lipemia
Vascular Effects of Triglyceride-rich Lipoproteins
Many types of cardiovascular disease begin when the layer of cells lining blood vessels (endothelial cells) start to function abnormally.
- Conditions
- Postprandial Period, Lipemia, Vasodilation, Vascular Resistance
- Trial name
- NCT01618071
- Testing
- High-fat meals varying in their fatty acid composition
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- King's College London