Clinical trials: Postprandial Period
Healthy
A Pilot Cross-over Bioequivalence Study of E3810 for Healthy Japanese Male (Under Postprandial Condition)
The purpose of this study is to assess pharmacokinetics of rabeprazole under postprandial condition.
- Trial name
- NCT01085708
- Testing
- rabeprazole
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eisai Co., Ltd.
Diabetes, Diabetes Mellitus, Type 2
A Trial to Assess the Effect of Liraglutide on Blood Triglyceride (Fat) Levels After a Meal in Type 2 Diabetics
This trial is conducted in Europe. The aim of this trial is to investigate whether a new compound, liraglutide, reduces the level of lipids (fat), including cholesterol, in the blood of type 2 diabetics, following a meal with…
- Trial name
- NCT00993304
- Testing
- liraglutide
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Novo Nordisk A/S
Healthy
Effect of Extruded Cereals Enriched With β-glucan on Postprandial Plasma Glucose and Serum Insulin Responses
β-glucan (BG) is a viscous dietary fiber present in barley and oats that, when added to carbohydrate containing foods, reduces the postprandial glycemic response (PPGR), which is considered to be beneficial to health.
- Trial name
- NCT05556837
- Testing
- Control Cereal, OBG Cereal, BBG Cereal
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Psychological Phenomena and Processes, Nutrition Physiological Phenomena
The Effects of Fiber on Appetite and Digestion Hormones
In this research study, investigators are interested in how certain dietary fibers in the diet affect certain hormones released from your intestine after eating and how these influence your appetite.
- Trial name
- FS (NCT01050101)
- Testing
- No fiber, Low GI high fiber viscous meal, Low GI high fiber non-viscous
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Complement-mediated Hemolytic Diseases
Effect of Food of NTQ5082 in Healthy Subjects
NTQ5082 capsule is a small molecule CFB factor inhibitor. The study is a randomized, open label, two sequence, two period, double crossover-design phase 1 clinical trial to evaluate the food effect on PK after a single oral…
- Trial name
- NCT06558656
- Testing
- NTQ5082 capsule
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
Type 2 Diabetes Mellitus
An Investigational Drug Study in Adults With Type 2 Diabetes on Basal Insulin (MK-0941-006)
A study to assess safety, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-0941 in Type 2 diabetics being treated with basal insulin.
- Trial name
- NCT00511472
- Testing
- MK-0941, LANTUS insulin
- Volunteers
- 70 people
- Sponsor
- Merck Sharp & Dohme LLC
Triglycerides, Weight Gain Trajectory
Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists
The goal of this clinical trial is to learn if drug RDX-002 works to treat high levels of fat (known as triglycerides, or TGs) in the blood in adults. It will also learn about the safety of drug RDX-002.
- Conditions
- Triglycerides, Weight Gain Trajectory, Cholesterol, Elevated
- Trial name
- NCT06640972
- Testing
- RDX-002
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Response Pharmaceuticals
Nutrition
Impact of Protein Formulations on the Stimulation of Muscle Protein Synthesis
The overall objective of this study is to determine the effects of ingesting protein that slowly releases amino acids into the blood vs.
- Trial name
- NCT07501403
- Testing
- Control Protein then Extended Release Nutritional Protein, Extended Release Protein then Control Nutritional Protein
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VitaKey Inc.
Post Prandial Distress Syndrome
A Dose-Ranging Study of ATI 7505 in Patients With Postprandial Distress Syndrome
To assess the efficacy of 3 oral dosing regimens of ATI 7505 compared to placebo in patients with PDS by comparing at the end of Day 42 the percentage of patients in each treatment group who have had adequate relief of…
- Trial name
- NCT00630370
- Testing
- 20 mg ATI 7505, 40 mg ATI 7505, 80 mg ATI 7505
- Where
- 64 sites in United States, Canada and 1 more
- Volunteers
- 6 people
- Sponsor
- Procter and Gamble
Blood Glucose, Postprandial
Effect of Escalating Doses of a Novel Viscous Polysaccharide on Postprandial Glycemia
To determine palatability and extent to which escalating doses of a novel highly viscous polysaccharide [NVP] reduces postprandial glycemia when added to a liquid and a solid meal.
- Trial name
- NCT00801814
- Testing
- PolyGlycopleX (PGX), PolyGlycopleX (PG), PolyGlycopleX
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Type 2 Diabetes
A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED)
This study will determine the effect of concomitant administration of sitagliptin and metformin on post-meal incretin hormone concentrations in healthy adults.
- Trial name
- NCT00975052
- Testing
- sitagliptin phosphate, Comparator: metformin, Comparator: sitagliptin and metformin
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy
Bed and Breakfast (B&B) Study
The primary objective is to determine which among high vs low Glycemic Index (GI) / Glycemic Responses (GR) interventions at breakfast or at dinner is the most effective for lowering glycemic response of the subsequent standard…
- Trial name
- NCT02927600
- Testing
- Low GI Breakfast, High GI Breakfast, Low GI Dinner
- Where
- Singapore
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Dyspepsia
Phase III, Long-term, Open-label Safety Study of Z-338
The primary objective of this study is to evaluate the long-term safety of 100 mg Z-338 TID in European subjects with FD.
- Trial name
- NCT01973790
- Testing
- Z-338
- Where
- 36 sites in Belgium, Bulgaria and 8 more
- Volunteers
- 207 people
- Sponsor
- Zeria Pharmaceutical
Type 1 Diabetes Mellitus
A Study of LY900014 in Participants With Type 1 Diabetes
The main purpose of this study is to evaluate the efficacy of the study drug LY900014 compared to insulin lispro, both in combination with insulin glargine or insulin degludec, in adults with type 1 diabetes (T1D).
- Trial name
- PRONTO-T1D (NCT03214367)
- Testing
- LY900014, Insulin Lispro, Insulin Glargine
- Where
- 172 sites in United States, Argentina and 18 more
- Volunteers
- 1,392 people
- Sponsor
- Eli Lilly and Company
Blood Glucose, Blood Insulin
Monitoring Postprandial Blood Glucose and Insulin in Fruit Snacks
The goal of this clinical trial is to compare the postprandial glucose and insulin responses after different fruit snacks compared to confection control in a healthy population
- Trial name
- NCT06458946
- Testing
- Fruit snack 1, Fruit snack 2, Fruit snack 3
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ocean Spray Cranberries, Inc.
Type 1 Diabetes Mellitus
Intranasal Insulin and Its Effect on Postprandial Metabolism in Comparison to Subcutaneous Insulin
The purpose of this study is to determine if glucose peaks higher and earlier after a meal when a patient is given intranasal insulin instead of conventional insulin treatment.
- Trial name
- NCT00850161
- Testing
- aspart, Nasulin™
- Sponsor
- CPEX Pharmaceuticals Inc.
Functional Dyspepsia
Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia
The study is conducted in patients with functional dyspepsia or chronic gastritis. The purpose of this study is to: assess whether the dose of Itopride Hydrochloride 150 mg extended release tablets, taken once daily has a similar…
- Trial name
- NCT06217393
- Testing
- Itopride Hydrochloride 150 mg extended release tablets, Itopride Hydrochloride 50 mg film coated tablets
- Where
- 19 sites in Armenia, Malaysia and 3 more
- Volunteers
- 564 people
- Sponsor
- Abbott
Nutritional and Metabolic Disease, Overweight
The Acute and Chronic Effects of Fruit Polyphenols on Chronic Disease (PPF)
1. The primary objective is to determine the effect of fruit polyphenols on postprandial lipoprotein triglyceride metabolism after consumption a standard high carbohydrate/fat breakfast meal with a beverage rich in fruit-derived…
- Trial name
- NCT01729949
- Testing
- Active Treatment Beverage
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Glucose, High Blood, Glucose, Low Blood
Post-prandial Glycemic Response to Fiber in Healthy Adults
This randomized, double-blind, comparator controlled trial evaluated the blood glucose and insulin responses in healthy adults, after consuming a high fiber or low fiber muffin top.
- Conditions
- Glucose, High Blood, Glucose, Low Blood, Meals
- Trial name
- NCT03252704
- Testing
- resistant starch (high fiber muffin top), control (low fiber muffin top)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ingredion Incorporated
Colorectal Cancer
Bioequivalence Study of Trifluridine and Tipiracil Tablets in Colorectal Cancer Patients
Trifluridine and Tipiracil Tablets is a nucleoside anti-metabolic and anti-cancer compound developed by Taiho (Dapeng) Co., Ltd., Japan, for the treatment of advanced colorectal cancer that inoperable resection, and progressed or…
- Trial name
- NCT03974594
- Testing
- Trifluridine and Tipiracil Tablets, TAS-102
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.