Clinical trials: Postprandial Period
Hyperglycemia, Postprandial
Effects of Arm Cycling and Leg Cycling on Postprandial Blood Glucose Levels in Healthy Persons
The literature has shown that exercise is effective in decreasing blood glucose levels. However, it remains less clear if there is any difference between muscle groups regarding the glucose-lowering effects of exercise.
- Trial name
- NCT04298710
- Testing
- Arm Cycling, Leg Cycling, Sitting
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Franklin Pierce University
Postprandial Hyperglycemia, Insulin High
The Effects of Vegetable Preloading on Postprandial Glycemia, Insulinaemia and Gastric Emptying
The objective of this study is to investigate the importance of leavy vegetable preloading on the postprandial glycaemic and insulinemic response in human subjects when consumed a specific amount of digestible carbohydrate from…
- Trial name
- APRE (NCT06640335)
- Testing
- Co-ingestion, 0 min preload, 5 min preload
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Type 2 Diabetes
Effect of Bile Acid Sequestration on Postprandial GLP-1 Secretion, Glucose Homeostasis and Gut Microbiota
Accumulating evidence suggests that bile acids and bacteria in our intestines may constitute essential components in the complex mechanisms regulating gut hormone secretion and glucose homeostasis.
- Trial name
- NCT02061124
- Testing
- Sevelamer 1600 mg TID for 7 days
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Hyperlipidemias, Triglycerides High
Effects of MCDG Oil on Postprandial Lipid Metabolism
It is well known that medium chain triglycerides (MCTs) and diacylglycerols (DGs) have effects on lowering circulating triglycerides (TGs).
- Trial name
- NCT03415568
- Testing
- LCT oil, MCDG oil
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Diabetes, Liver
Foxtail Millet Based Dietary Intervention for Postprandial Glycemic Management Among Obese Diabetic Patients
This randomized controlled trial evaluated the effectiveness of foxtail millet (Setaria italica (L.) P. Beauv.) muffin supplementation on postprandial glycemic management among obese patients with type 2 diabetes mellitus.
- Conditions
- Diabetes, Liver, Lipid Profiles
- Trial name
- NCT07699250
- Testing
- T0, T1, T2
- Where
- Pakistan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Healthy Participants
GPR146 and Cholesterol Metabolism
Blood cholesterol balance is regulated by an interplay between the small intestine and the liver. Recently, a new protein (cholesin) was discovered, which is secreted by intestinal cells after dietary cholesterol intake.
- Trial name
- GPR146 (NCT07142317)
- Testing
- Cholesterol-poor, plant sterol-poor shake, Cholesterol-rich, plant sterol-poor shake, Cholesterol-rich, plant sterol-rich shake
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Postprandial Hyperglycemia, Insulin Resistance
Nut Intake At Night: Effect on Postprandial Glycaemia
There is some evidence to suggest that the timing of a meal intake directly impacts postprandial insulin and glucose responses, with meals consumed later during the day being more metabolically detrimental that the same meals…
- Trial name
- NCT04965896
- Testing
- Control meal, Nut meal
- Volunteers
- healthy volunteers welcome
- Sponsor
- Monash University
Type 2 Diabetes, Postprandial Hypotension
Acarbose, Postprandial Hypotension and Type 2 Diabetes
Postprandial hypotension carries a risk of significant morbidity and morbidity including syncope, falls, dizziness, fatigue, stroke and myocardial infarction.
- Trial name
- NCT02043886
- Testing
- Acarbose
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Type 2 Diabetes Mellitus
The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes
The purpose of this investigation is to evaluate whether exenatide, a type 2 diabetes medication, will improve the function of the innermost part of the arterial wall called the endothelium after a fat-enriched meal and to…
- Trial name
- NCT01181986
- Testing
- Exenatide SC, Exenatide IV, Exendin-9
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Carl T. Hayden VA Medical Center
Malnutrition; Diabetes, Malnutrition; Protein
Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults
The study looks at the comparative effects of food products made with pea, lentil, and oat flour of various particle sizes on postprandial glycemic response, appetite and food intake, and amino acid release in healthy adults.
- Conditions
- Malnutrition; Diabetes, Malnutrition; Protein, Obesity
- Trial name
- PLO (NCT05291351)
- Testing
- Crackers made with whole, coarse, or fine pea and/or wheat flour, Crackers made with whole, coarse, or fine lentil and/or wheat flour, Porridge made with oat flour
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity and Overweight, Moderately Obese
EXploratory Study on Postprandial Energy Metabolism
This exploratory, double-blinded clinical trial on 66 randomized adults aged 50 to 70 years with moderate overweight or obesity but considered metabolically healthy will consist of comparing metabolic and microbiota parameters…
- Trial name
- EXPEM (NCT06786052)
- Testing
- Probiotic
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Healthy Men
The Acute Effects of Interesterification of Commercially Used Fats on Postprandial Lipaemia and Satiety
The purpose of this study is to investigate whether there are differences in postprandial metabolic indices following interesterified fats used in commercial spreads versus the corresponding un-interesterified blend.
- Trial name
- INTERFAT (NCT02365987)
- Testing
- Interesterified blend of palm kernal and plam stearin, Un-interesterified blend of palm kernal and plam stearin
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes Mellitus, Type 2
A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects
An open-label, phase II study to assess the acute and chronic effects of empagliflozin (BI 10773)on fasting and postprandial glucose homeostasis in patients with IGT and type 2 diabetes mellitus and assess the acute effects of…
- Trial name
- NCT01248364
- Testing
- BI 10773
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Blood Sugar (Glucose) Control, Blood Vessel (Vascular) Dysfunction
Whey Protein Effects on Gycemic Control and Vascular Function
Risk for heart and blood vessel diseases is increased when blood sugar rises. Blood vessel dysfunction is common to such diseases. Elevated blood sugar after eating promotes blood vessel dysfunction.
- Trial name
- NCT01814358
- Testing
- Whey protein powder, Control protein
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Obesity
A Research Study Looking at How NNC0487-0111 Affects Food Intake, Appetite and Metabolism After Meals in People With Obesity
The purpose of this clinical study is to look at if/how much NNC0487-0111 affects food intake, appetite and metabolism in participants with obesity when compared to placebo. There are 2 study treatments in this study.
- Trial name
- NCT07508020
- Testing
- NNC0487-0111
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Novo Nordisk A/S
T1D, T1DM
Pre-Exercise Whey and Pea Protein in Adolescents With Type 1 Diabetes
The goal of this clinical trial is to learn whether drinking whey protein or pea protein before exercise affects blood sugar levels and appetite in adolescents with type 1 diabetes.
- Trial name
- NCT07836673
- Testing
- low whey protein, moderate whey protein, low Pea protein
- Volunteers
- 30 people
- Sponsor
- University of Jordan
Diabetes Mellitus, Gastroparesis
Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People
The purpose of this study is to determine the effects of the drug lixisenatide on blood sugar levels, stomach emptying, blood pressure and heart rate, release of gut hormones and blood flow in the gut after a glucose drink in…
- Trial name
- Lixi (NCT02308254)
- Testing
- Lixisenatide
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Type 2 Diabetes Mellitus
Glycemic and Satiety Response Study of Fibre-Enriched Pudding Products
The purpose of this study is to determine the specific properties of a variety of dietary fibres that lead to different postprandial glycemic and satiety responses in individuals at risk for type 2 diabetes.
- Trial name
- Pudding (NCT02289612)
- Testing
- Yellow Mustard Gum Fibre, Soluble Flaxseed Gum Fibre, Fenugreek Gum Fibre
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Guelph
Cardiovascular Diseases
ARROW:identificAtion of postpRandial biomaRkers tOWards Cardiovascular Prevention
The purpose of this study is to better understand the association between the postprandial biomarker responses after a food challenge with the development of cardiovascular diseases in healthy subjects
- Trial name
- NCT03531879
- Where
- Switzerland
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Type 2 Diabetes Mellitus
Effects of PCSK9 Inhibition by Evolocumab on Postprandial Lipid Metabolism in Type 2 Diabetes
Postprandial lipemia is highly prevalent in type 2 diabetes subjects even with normal fasting triglyceride values. Humans are mostly in a postprandial rather than in a fasting state and therefore non-fasting triglyceride values…
- Trial name
- NCT02948777
- Testing
- Evolocumab
- Where
- Finland
- Volunteers
- 14 people
- Sponsor
- Marja-Riitta Taskinen
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