Clinical trials: Postprandial Period
Type 2 Diabetes
Cocoa Polyphenols and Postprandial Metabolism in Type 2 Diabetes
This study aims to investigate the postprandial effects of cocoa supplementation in glucose and lipids, and surrogate markers of atherosclerosis in patients with type 2 diabetes.
- Trial name
- NCT01886989
- Testing
- Cocoa polyphenols
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Arpita Basu
Hypoglycemia, Cerebral Blood Flow
External Carotid Blood Flow in Individuals With Post-Bariatric Hypoglycemia
This is a pilot study (small-scale study) that aims to understand more about how blood flow changes in people who have low blood sugar after bariatric surgery (post-bariatric hypoglycemia) compared to those who have had surgery…
- Trial name
- NCT07082478
- Testing
- in-ear device measuring blood flow
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Joslin Diabetes Center
Abdominal Obesity, Metabolic Syndrome
The Effect of Whey Protein and Dietary Fibers on Risk Markers of the Metabolic Syndrome and Bone Health
The prevalence of overweight and lifestyle related diseases such as cardiovascular disease (CVD) and type 2 diabetes (T2D) is increasing world wide.
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- MERITS (NCT02931630)
- Testing
- Whey protein powder, Maltodextrin powder, High fiber bread
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Healthy
Palatability and Postprandial Sensations
Aim: to determine the effect of palatability on the cognitive (satiation/fullness) and emotive (digestive well-being/mood) responses to meal ingestion.
- Trial name
- NCT03134365
- Testing
- Mixed meal, Combined meal
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Type 1 Diabetes Mellitus
Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus
Humalog and Humulin-R (recombinant human insulin) are Food and Drug Administration (FDA) approved medications for the treatment of diabetes mellitus.
- Trial name
- NCT00774800
- Testing
- Humalog, Humulin-R, Recombinant human hyaluronidase PH20 (rHuPH20)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Halozyme Therapeutics
Amyotrophic Lateral Sclerosis (Healthy Volunteers)
A Study in Healthy Adult Male & Female Participants to Assess the Amount of the Study Medicine (SAR443820) Absorbed by the Body, When Given Orally in Fasted Condition as a Tablet Versus as a Capsule (Part 1) and When Given Orally as a Tablet in Fasted Condition Versus as a Tablet After Food (Part 2)
Part 1: This is an open label, balanced randomized, single dose, 2-sequence, 2-period (period 1 and period 2), 2-treatment crossover (between Treatment A and Treatment B for Part 1), study part to determine the relative…
- Trial name
- NCT05797701
- Testing
- SAR443820
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sanofi
Type 1 Diabetes Mellitus
A Study Comparing LY900014 to Insulin Lispro (Humalog) in Children and Adolescents With Type 1 Diabetes
The reason for this study is to compare the study drug LY900014 to insulin lispro (Humalog) in children and adolescents with type 1 diabetes (T1D).
- Trial name
- PRONTO-Peds (NCT03740919)
- Testing
- LY900014, Insulin Lispro, Insulin Glargine
- Where
- 111 sites in United States, Austria and 16 more
- Volunteers
- 751 people
- Sponsor
- Eli Lilly and Company
Nutrition, Mastication
Mastication and Energy Expenditure in Normal Weight and Obese People
The objective of the study is to analyze the specific role of physical properties of food and mastication in the cephalic phase reflex of thermogenesis, and the involvement of the autonomic nervous system in the implementation of…
- Trial name
- MASTICAL (NCT04050930)
- Testing
- Mastication
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Healthy Men
The Acute Effects of Interesterification of Commercially Used Fats on Postprandial Lipaemia and Satiety
The purpose of this study is to investigate whether there are differences in postprandial metabolic indices following interesterified fats used in commercial spreads versus the corresponding un-interesterified blend.
- Trial name
- INTERFAT (NCT02365987)
- Testing
- Interesterified blend of palm kernal and plam stearin, Un-interesterified blend of palm kernal and plam stearin
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- King's College London
Gut Microbiome, Prebiotic
ZOE BIOME Study: Biotics Influence on Microbiome Ecosystem
The differences observed in host gut microbiome communities between health and disease states, and between different dietary patterns, has led to an increase in the use of dietary modulations to influence microbiome composition…
- Conditions
- Gut Microbiome, Prebiotic, Probiotic, Postprandial Period
- Trial name
- NCT06231706
- Testing
- Prebiotic-like nut and seed mix, Bread Crouton, Probiotic capsule
- Where
- United Kingdom
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes After Total Pancreatectomy
The Impact of Lixisenatide on Postprandial Glucose Tolerance in Pancreatectomised Subjects
Postprandial glucose (PPG) excursions are not only determined by insulin-mediated glucose disposal and endogenous glucose production (regulated by insulin and glucagon); also the rate of gastric emptying constitutes an important…
- Trial name
- Px-Lixi (NCT02640118)
- Testing
- Lixisenatide, Standardized liquid meal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Adiposity, Insulin Sensitivity
Metabolic Adaptations to High-fat Diet
The purpose of this study is to understand how the body's response after a meal is influenced by insulin and sugar in the blood.
- Conditions
- Adiposity, Insulin Sensitivity, Impaired Glucose Tolerance, Metabolic Disturbance
- Trial name
- MetFlexHFD (NCT06537401)
- Testing
- Hypercaloric, High Fat Diet
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- George Washington University
Hyperglycemia, Postprandial
Effects of Berry Nectars Sweetened With Inverted Sugar on Post-meal Blood Sugar
Berries have been shown to improve postprandial glucose and insulin responses to sucrose. During processing and storage of berry products, sucrose is inverted to glucose and fructose.
- Trial name
- NCT02743130
- Testing
- Blackcurrant Nectar, Lingonberry Nectar, Reference
- Where
- Finland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Diabetes Mellitus, Postprandial Lipemia
Effects of Sitagliptin on Postprandial Lipemia in Men With Type 2 Diabetes
Sitagliptin is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-4), and has been shown to reduce fasting and postprandial glucose levels in patients with type 2 diabetes mainly through incretin hormone-mediated…
- Trial name
- NCT00660075
- Testing
- Sitagliptin
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Laval University
Obesity, Healthy
Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6
The overall purpose of this explorative yet quantitative study project is to understand how blocking IL-6 signaling leads to the expansion of adipose tissue mass in humans in vivo.
- Trial name
- NCT04687540
- Testing
- Tocilizumab, Saline 0.9%
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type 1 Diabetes Mellitus
A Trial to Investigate Post Prandial Blood Glucose Control With Fast-acting Human Insulin HinsBet® Compared to Insulin Lispro (Humalog®) and Regular Human Insulin (Huminsulin® Normal) After Ingestion of a Standardized Meal in Subjects With T1DM
This is a 2 centres, randomised, double blind, three-treatment, three-period cross-over trial in subjects with type 1 diabetes mellitus.
- Trial name
- NCT02739906
- Testing
- BioChaperone Human Insulin (HinsBet®), Insulin Lispro (Humalog®), Regular human insulin (Huminsulin® Normal)
- Where
- 2 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Adocia
Gastroparesis
Escalating Temporary Gastric Electrical Stimulation (GES) for Severe Gastroparesis
The purpose of this study is to determine the physiologic effects of temporary gastric electrical stimulation in subjects with severe gastroparesis.
- Trial name
- TempGES (NCT02164591)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Indiana University
Protein Digestion Kinetics
Postprandial Blood Amino Acid Response
This study was designed to obtain information about the change in postprandial amino acids in blood over time, after consumption of different dairy products with varying proportions of whey protein and caseins, and different…
- Trial name
- PARROT-2 (NCT03313791)
- Testing
- Whey protein concentrate, Yoghurt, 50%whey-50% casein (Standard)
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
Postprandial Blood Glucose
Effect of an Arabinogalactan Product
Dietary fiber is an important nutrient that supports gastrointestinal function as well as blood glucose and cholesterol maintenance.
- Trial name
- NCT04005924
- Testing
- arabinogalactan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Biofortis, Merieux NutriSciences
Postprandial Hyperglycemia
Metabolic Effects of High-amylose Wheat-based Breads
The amylose-amylopectin ratio influences starch properties. A higher amylose content is associated with slower starch digestion thus reducing the postprandial plasma glucose response and improving the overall postprandial…
- Trial name
- NCT03899974
- Testing
- Test meal
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federico II University
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