Clinical trials: Postprandial Period
Biomarker
Exploring the Potential of Finger Prick Blood for Assessment of BIOmarkers for LOw Grade Inflammation and CVD Risk
There are currently no minimally invasive techniques for the measurement of lipopolysaccharide (LPS) and Apo-B48 that can be used in samples collected in field settings.
- Trial name
- BIOLOGIC (NCT04996589)
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Wageningen University and Research
Diabetes Mellitus, Type 1
Postprandial Blood Glucose Control and Gastric Emptying in Type 1 Diabetes: Pathogenetic Factors and Therapeutic Options
This study evaluates the prevalence of gastric emptying (GE) in type 1 diabetic patients (DM1) free of chronic complications in comparison with a group of healthy control subjects.
- Trial name
- NCT02365740
- Testing
- gastric emptying test, gut hormones determination, Continuous Glucose Monitoring
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University
Type 2 Diabetes
Effect of Breakfast or Omission of Breakfast in T2D
The investigators will explore the effect of omission of breakfast on postprandial hyperglycemia and insulin and intact GLP-1 response after subsequent meals in type 2 diabetic patients
- Trial name
- OB-B (NCT01571310)
- Testing
- Omitted Breakfast, Breakfast
- Where
- 2 sites in Israel, Venezuela
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Cardiovascular Diseases, Heart Diseases
Diabetes, Lipoproteins and Accelerated Vascular Disease
To better understand the excess cardiovascular disease associated with diabetes mellitus.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis
- Trial name
- NCT00005479
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Columbia University
Spinal Cord Injuries
Diet and Exercise Solutions to Postprandial Hypotension
The purpose of this study is to determine if a low glycemic diet and lower-body electrical stimulation can reduce postprandial hypotension in individuals with chronic spinal cord injury.
- Trial name
- NCT06882460
- Testing
- Low glycemic load, Electrical stimulation exercise, High glycemic load diet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Ohio State University
Type 2 Diabetes Mellitus
1,5-AG as a Marker of Postprandial Hyperglycemia and Glucose Variability in Well-controlled Type 2 Diabetes Mellitus
The aim of this study was to evaluate the correlation between 1,5-Anhydroglucitol in patients with HbA1C <7%, and glycemic excursions as assessed by the continuous glucose monitoring system compared to fructosamine.
- Trial name
- NCT01161797
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Kyunghee University Medical Center
Obesity
A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT01797042
- Testing
- Dietary Compliance
- Where
- United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Protein Digestion Kinetics
Real-time Amino Acid Profiling
This study was designed to obtain information about the effect of new combinations of dairy proteins, in small servings with high protein concentrations, on postprandial amino acid kinetics in blood in an older population.
- Trial name
- RAP (NCT03547362)
- Testing
- Casein, Dairy protein blend 1, Whey protein
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
Metabolic Syndrome
Pea Protein and Postprandial Response (PEA)
The main objective is to investigate the postprandial effect of arginine-rich protein (i.e. pea-protein) on metabolic control, inflammation and endothelial function after a high-fat meal in subjects with characteristics of the…
- Trial name
- PEA (NCT01215370)
- Testing
- High-fat shake with Pea protein, High-fat shake with Pea protein hydrolysate, High-fat shake - Control
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Sedentary Behavior, Lipid Metabolism Disorder
Preventing Exercise Resistance With Sedentary Interruptions
The goal of this randomised cross-over trial is to learn about the interaction between sedentary behaviour throughout the day and the metabolic effect of an exercise bout on that same day in office workers with an increased risk…
- Conditions
- Sedentary Behavior, Lipid Metabolism Disorder, Exercise
- Trial name
- PERSI (NCT06277713)
- Testing
- Standing interruptions, Exercise bout, Sedentary
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Hyperlipidemias, Inflammation
The Effects of Homogenized and Unhomogenized Milk on Postprandial Metabolism in Healthy Overweight Men
The purpose of this study is to compare the effects of homogenized, unhomogenized and skimmed milk on postprandial metabolism in healthy overweight men
- Conditions
- Hyperlipidemias, Inflammation, Atherosclerosis
- Trial name
- NCT01317524
- Testing
- Homogenized milk, Unhomogenized milk, Skimmed Milk
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes Mellitus
A Study to Evaluate the Effect of Ranolazine on Postprandial Glucagon in Subjects With Type 2 Diabetes.
To explore the mechanism of action of ranolazine as a potential treatment for type 2 diabetes mellitus (T2DM).
- Trial name
- NCT01843127
- Testing
- Ranolazine, Exenatide
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Gilead Sciences
Glycaemia
The Effect of Hydration on Postprandial Metabolic Responses
Certain populations, such as industrial workers and endurance athletes are particularly susceptible to dehydration due to exposure to heat for long periods of time causing evaporative water loss via sweating.
- Trial name
- NCT06825962
- Testing
- Water intake, Water restriction
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Cigarette Smoking, Coronary Heart Disease
Exercise and Coronary Heart Disease Risk Markers in Male Smokers and Non-Smokers
The present study will investigate the effect of acute exercise on fasting and postprandial risk markers for coronary heart disease (CHD) in healthy male cigarette smokers and non-smokers.
- Conditions
- Cigarette Smoking, Coronary Heart Disease, Cardiovascular Risk Factor, Insulin Resistance
- Trial name
- NCT03735186
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy
Effects of Co-ingesting a Low/High GI Meal With Different Fat Saturation on Postprandial Glucose, Insulin, and Triacylglycerol Responses in Healthy Participants
It is now recognized that diet plays a critical role in the etiology and management of the chronic diseases such as diabetes, obesity and cardiovascular disease.
- Trial name
- NCT02585427
- Testing
- low glycemic index rice, high glycemic index rice, butter, olive oil and grapeseed oil
- Where
- Singapore
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Cardiovascular Risk Factors
A Study of Different Types of Fatty Acid on Risk Factors for Heart Disease
Experimental elevation of non-esterified fatty acids (NEFA) impairs endothelial function and insulin sensitivity but the impact of NEFA composition is unknown.
- Trial name
- eFAIRE (NCT01351324)
- Testing
- Absence or presence of fish oil
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Reading
Personalized Nutrition In Children, Glucose, High Blood
Personalizing Mediterranean Diet in Children.
Investigating glucose response to Mediterranean and regular diets in healthy children in order to develop specific pediatric machine-learning for predicting the personalized glucose response to food for individual children.
- Conditions
- Personalized Nutrition In Children, Glucose, High Blood, Diet Habit
- Trial name
- NCT03627923
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science
Lipid Metabolism, Glucose Metabolism
Digital Twin - Modelling Postprandial Triglyceride and Glucose Responses
Giving personalised dietary advice will help mitigate the postprandial increases in TG and glucose levels, and will assist in the battle against the increase in nutrition-related diseases, such as cardiovascular diseases.
- Trial name
- NCT05313594
- Testing
- Mixed meal challenge test, MRI, DEXA
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Hyperinsulinemic Hypoglycemia, Postprandial Hypoglycemia
Treatment of Post-bariatric Hypoglycaemia
This is an investigator-initiated, proof-of-concept, randomised, double-blind, placebo-controlled, single-centre phase II study aiming to evaluate the efficacy, safety and tolerability of self-administered subcutaneous 120 µg…
- Trial name
- SHERRY (NCT04836273)
- Testing
- Dasiglucagon, HyoPen
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Filip Krag Knop
Functional Dyspepsia
Functional Dyspepsia: Validation of the Leuven Postprandial Distress Scale (LPDS) in a Placebo-controlled Trial
No instrument is available for the assessment of the symptoms in patients suffering from functional dyspepsia - postprandial distress syndrome patients - PDS. Indeed PDS is an unmet clinical need in drug development.
- Trial name
- NCT04464369
- Testing
- itopride
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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